HOME >> BIOLOGY >> NEWS
Homing in on a receptor for the fifth taste

Humans can recognize five tastes: bitter, salty, sour, sweet and umami. Of the five, however, umami is the most difficult to describe its the flavor associated with monosodium glutamate (MSG). Now, researchers have identified a taste receptor that responds to amino acids, including umami, and they hope to develop a more precise description of the molecular events that allow the brain to perceive the five different tastes.

With the discovery of the new receptor, scientists have now identified taste receptors for amino acids, bitter and sweet tastes. Given that many amino acids are essential components of our diet, this work may also aid understanding of how animals, including humans, regulate nutritional intake to achieve a balanced diet. Better understanding of taste receptors may permit scientists in the food industry to formulate new products that have specific tastes.

A research team led by Howard Hughes Medical Institute investigator Charles S. Zuker at the University of California, San Diego, and Nicholas J. P. Ryba of the National Institutes of Health reported the identification of an amino-acid taste receptor in an advanced online publication in Nature on February 25, 2002.

Zukers and Rybas groups previously collaborated in discovering sweet and bitter taste receptors. After they had identified those receptors, they set their sights on finding a taste receptor for amino acids, reasoning that one must exist because it had long been known that humans have the ability to taste umami and other amino acids. "Since amino acids are essential building blocks of biologically important molecules such as proteins, it made evolutionary sense for there to be a taste pathway that would make amino acids attractive to consume," said Zuker.

In their search for the amino acid receptor, the scientists focused on T1R receptors, a family of proteins that are distantly relat
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
25-Feb-2002


Page: 1 2 3

Related biology news :

1. Homing in on better bone marrow transplants
2. Ovarian cancer sheds tumor suppression with loss of estrogen receptor
3. Alterations in vitamin D receptor gene increase prostate, breast cancer risk
4. Two-pronged attack targeting EGF receptor hinders cancer cell growth
5. Tamoxifen stimulates breast cancer growth following alteration of estrogen receptor
6. Dioxin-receptor network identified
7. Inhibition of insulin-like growth factor receptor-1 as promising anticancer therapeutic
8. Scientists at Scripps Research Institute describe structure of receptor on surface of 1918 flu virus
9. Activation of receptor ups development of precancerous intestinal polyps
10. Researchers find an association between alcohol dependence and the GABAA receptor gene GABRG3
11. The dopamine receptor D1 gene and ADHD: A piece of the genetic puzzle?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2017)... YORK , Feb. 8, 2017 About ... individual,s voice to match it against a stored ... such as pitch, cadence, and tone are compared ... require minimal hardware installation, as most PCs already ... for different transactions. Voice recognition biometrics are most ...
(Date:2/7/2017)... MINNETONKA, Minn. , Feb. 7, 2017   ... that supports the entire spectrum of clinical research, is ... iMedNet , its innovative, highly flexible and ... iMedNet customers. iMedNet is a ... only provides Electronic Data Capture (EDC), but also delivers ...
(Date:2/3/2017)... Feb. 3, 2017 A new independent identity ... Partners, LLP (IdSP) . Designed to fill a critical ... identity market, founding partners Mark Crego and ... years just in identity expertise that span federal governments, ... leadership. The Crego-Kephart combined expertise has a common theme ...
Breaking Biology News(10 mins):
(Date:2/17/2017)... 17, 2017  Protagonist Therapeutics, Inc. (NASDAQ: PTGX) ... oral peptide drug candidates, PTG-100 and PTG-200, at ... Crohn,s and Colitis Organization (ECCO).  The ECCO congress ... from February 15 – 18, 2017. ... on Protagonist drug candidates PTG-100 and PTG-200. PTG-100, ...
(Date:2/16/2017)... GREENWICH, Conn. , Feb. 16, ... focused on venture growth investments in biotechnology and ... Josh Richardson , M.D. to Managing Director. ... companies.  He is a board observer at InfaCare ... Longitude,s investments in Aimmune Therapeutics, Akebia Therapeutics, Cadence ...
(Date:2/16/2017)... 2017   Capricor Therapeutics, Inc. (NASDAQ: ... developing first-in-class biological therapies for cardiac and other ... to terminate its license agreement with the Mayo ... Cenderitide. "Our decision to return these ... our efforts to advance our core cell and ...
(Date:2/16/2017)... Feb. 16, 2017  Dermata Therapeutics, LLC, a ... treat a variety of dermatological diseases, today announced ... financing and entered into a $5 million credit ... to use the capital for general corporate purposes ... in the treatment of serious diseases treated by ...
Breaking Biology Technology:
Cached News: