HOME >> BIOLOGY >> NEWS
Homing in on a receptor for the fifth taste

Humans can recognize five tastes: bitter, salty, sour, sweet and umami. Of the five, however, umami is the most difficult to describe its the flavor associated with monosodium glutamate (MSG). Now, researchers have identified a taste receptor that responds to amino acids, including umami, and they hope to develop a more precise description of the molecular events that allow the brain to perceive the five different tastes.

With the discovery of the new receptor, scientists have now identified taste receptors for amino acids, bitter and sweet tastes. Given that many amino acids are essential components of our diet, this work may also aid understanding of how animals, including humans, regulate nutritional intake to achieve a balanced diet. Better understanding of taste receptors may permit scientists in the food industry to formulate new products that have specific tastes.

A research team led by Howard Hughes Medical Institute investigator Charles S. Zuker at the University of California, San Diego, and Nicholas J. P. Ryba of the National Institutes of Health reported the identification of an amino-acid taste receptor in an advanced online publication in Nature on February 25, 2002.

Zukers and Rybas groups previously collaborated in discovering sweet and bitter taste receptors. After they had identified those receptors, they set their sights on finding a taste receptor for amino acids, reasoning that one must exist because it had long been known that humans have the ability to taste umami and other amino acids. "Since amino acids are essential building blocks of biologically important molecules such as proteins, it made evolutionary sense for there to be a taste pathway that would make amino acids attractive to consume," said Zuker.

In their search for the amino acid receptor, the scientists focused on T1R receptors, a family of proteins that are distantly relat
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
25-Feb-2002


Page: 1 2 3

Related biology news :

1. Homing in on better bone marrow transplants
2. Ovarian cancer sheds tumor suppression with loss of estrogen receptor
3. Alterations in vitamin D receptor gene increase prostate, breast cancer risk
4. Two-pronged attack targeting EGF receptor hinders cancer cell growth
5. Tamoxifen stimulates breast cancer growth following alteration of estrogen receptor
6. Dioxin-receptor network identified
7. Inhibition of insulin-like growth factor receptor-1 as promising anticancer therapeutic
8. Scientists at Scripps Research Institute describe structure of receptor on surface of 1918 flu virus
9. Activation of receptor ups development of precancerous intestinal polyps
10. Researchers find an association between alcohol dependence and the GABAA receptor gene GABRG3
11. The dopamine receptor D1 gene and ADHD: A piece of the genetic puzzle?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/17/2016)... -- AIC announces that it has just released a new white paper authored by Zettar ... high speed data transfer storage solutions. Photo - http://photos.prnewswire.com/prnh/20161116/440463 ... ... ... Setting up a high performance computing or HPC system can be ...
(Date:11/15/2016)... , Nov. 15, 2016  Synthetic Biologics, ... developing therapeutics focused on the gut microbiome, today ... of 25,000,000 shares of its common stock and ... stock at a price to the public of ... to Synthetic Biologics from the offering, excluding the ...
(Date:11/14/2016)... Nov. 14, 2016  xG Technology, Inc. ("xG" or ... critical wireless communications for use in challenging operating environments, ... 30, 2016. Management will hold a conference call to ... p.m. Eastern Time (details below). Key Recent ... $16 million binding agreement to acquire Vislink Communication Systems. ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... UK (PRWEB) , ... December 08, 2016 , ... ... precision light to control cells — optogenetics — is key to exciting advances ... of the art, spatially patterned light projected via free-space optics stimulates small, transparent ...
(Date:12/8/2016)... England , December 8, 2016 ... has expanded its customisable SureSeq™ NGS panel range with the ... allowing fast and cost-effective study of variants in familial hypercholesterolemia ... number variation (CNV) detection on a single small panel and ... hotspot content. This includes all exons for LDLR , ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... commercial launch of flexible packaging for their exceptionally efficient human mesenchymal stem/stromal ... extends RoosterBio’s portfolio of bioprocess media products engineered to radically streamline culture ...
(Date:12/8/2016)...  Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the ... and commercializing products to treat rare diseases where ... the long-term follow-up data from its Phase 2 ... Defense Regulator (IDR), in the treatment of oral ... undergoing chemoradiation therapy (CRT).  The additional 12-month safety ...
Breaking Biology Technology:
Cached News: