HOME >> BIOLOGY >> NEWS
Homing in on a receptor for the fifth taste

Humans can recognize five tastes: bitter, salty, sour, sweet and umami. Of the five, however, umami is the most difficult to describe its the flavor associated with monosodium glutamate (MSG). Now, researchers have identified a taste receptor that responds to amino acids, including umami, and they hope to develop a more precise description of the molecular events that allow the brain to perceive the five different tastes.

With the discovery of the new receptor, scientists have now identified taste receptors for amino acids, bitter and sweet tastes. Given that many amino acids are essential components of our diet, this work may also aid understanding of how animals, including humans, regulate nutritional intake to achieve a balanced diet. Better understanding of taste receptors may permit scientists in the food industry to formulate new products that have specific tastes.

A research team led by Howard Hughes Medical Institute investigator Charles S. Zuker at the University of California, San Diego, and Nicholas J. P. Ryba of the National Institutes of Health reported the identification of an amino-acid taste receptor in an advanced online publication in Nature on February 25, 2002.

Zukers and Rybas groups previously collaborated in discovering sweet and bitter taste receptors. After they had identified those receptors, they set their sights on finding a taste receptor for amino acids, reasoning that one must exist because it had long been known that humans have the ability to taste umami and other amino acids. "Since amino acids are essential building blocks of biologically important molecules such as proteins, it made evolutionary sense for there to be a taste pathway that would make amino acids attractive to consume," said Zuker.

In their search for the amino acid receptor, the scientists focused on T1R receptors, a family of proteins that are distantly relat
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
25-Feb-2002


Page: 1 2 3

Related biology news :

1. Homing in on better bone marrow transplants
2. Ovarian cancer sheds tumor suppression with loss of estrogen receptor
3. Alterations in vitamin D receptor gene increase prostate, breast cancer risk
4. Two-pronged attack targeting EGF receptor hinders cancer cell growth
5. Tamoxifen stimulates breast cancer growth following alteration of estrogen receptor
6. Dioxin-receptor network identified
7. Inhibition of insulin-like growth factor receptor-1 as promising anticancer therapeutic
8. Scientists at Scripps Research Institute describe structure of receptor on surface of 1918 flu virus
9. Activation of receptor ups development of precancerous intestinal polyps
10. Researchers find an association between alcohol dependence and the GABAA receptor gene GABRG3
11. The dopamine receptor D1 gene and ADHD: A piece of the genetic puzzle?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/20/2016)... LONDON , Jan. 20, 2016 A ... positioned to directly benefit from the explosion in genomics ... from Howe Sound Research. A range of dynamic trends ... ...... - personalized medicine - pharmacogenomics - pathogen ... economies with large markets - greater understanding of the ...
(Date:1/20/2016)... SAN JOSE, Calif. , Jan. 20, 2016 ... leading developer of human interface solutions, today announced ... touch controller solution for wearables and small screen ... appliances such as printers. Supporting round and rectangular ... the S1423 offers excellent performance with moisture on ...
(Date:1/15/2016)... , Jan. 15, 2016 Recent publicized ... small to find new ways to ensure data security ... iOS and Android that ties ... biometrics, transforming it into a hardware authorization token. Customer ... swipe their fingerprint on their KodeKey enabled device to ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... -- Wellcentive today announced it has been selected by FamilyCare ... community care organization (CCO) with more than 130,000 ... and care management solutions and services. Wellcentive,s capabilities ... managers, analysts and care managers while providing insight ... members. Oregon . ...
(Date:2/11/2016)... , Feb. 11, 2016  Dovetail Genomics™ LLC today ... beta program for a planned metagenomic genome assembly service. ... company,s metagenomic genome assembly method in a talk on ... Biology & Technology conference in Orlando, Fla. ... highly complex datasets is difficult. Using its proprietary ...
(Date:2/11/2016)... WASHINGTON , Feb. 11, 2016   BioInformant ... strategic report, "Stem Cell Research Products, Opportunities, Tools, and ... 2020. ... specialize in the stem cell industry, BioInformant has more ... of the stem cell market, by stem cell type. ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... a new agreement with Bankok,Thailand-based Global Stem Cells Network (GSCN) to distribute exosome ... Latin American countries, including Mexico, Costa Rica, Dominican Republic, Colombia, Argentina, Nicaragua, Panama, ...
Breaking Biology Technology:
Cached News: