HOME >> BIOLOGY >> NEWS
Homocysteine: A Possible Risk Factor For Alzheimer's Disease

Scientists at the Universities of Oxford, in the UK, and Bergen, Norway, have found an association between pathologically-confirmed Alzheimer's disease and moderately elevated blood levels of the amino acid, homocysteine. A moderate elevation in blood levels of homocysteine is a known risk factor for heart disease and stroke.

Researchers found that 76 patients in the Oxford Project to Investigate Memory and Ageing (OPTIMA) who had pathologically-confirmed Alzheimer's disease had elevated blood levels of homocysteine and lower blood levels of folate and vitamin B12 (the vitamins which control homocysteine levels) than 108 age-matched control subjects.

These latest findings, which have yet to be published, were reported yesterday (Monday 27 April) in Nijmegen, Netherlands, at the second International Conference on Homocysteine Metabolism. However, the authors of the report, `Hyperhomocysteinemia: an independent risk factor for histopathologically-confirmed Alzheimer's disease - Professor David Smith, Dr R Clarke, Dr K A Jobst, Ms L Sutton, Professor P M Ueland, and Professor H Refsum - stressed that these biochemical changes in the blood could be a consequence, rather than a cause, of Alzheimer's disease, and that further work is required to distinguish between these two interpretations.

In particular, clinical trials over a number of years will be needed to determine if lowering homocysteine levels, by means of dietary supplementation with folic acid and vitamin B12, influences the development of Alzheimer's disease. Individuals should not take extra folic acid without consulting their doctor.

Profesor David Smith, Chairman of the Department of Pharmacology at Oxford and head of OPTIMA, said: `These findings are important because they provide a testable hypothesis that it may be possible to prevent or delay the progression of Alzheimer's disease in a proportion of potential sufferers. Howev
'"/>

Contact: Gill Sanders or Nicky Old
gill.sanders@admin.ox.ac.uk
44 (0)1865 278181
University of Oxford
28-Apr-1998


Page: 1 2

Related biology news :

1. Possible new cure for psoriasis
2. Possible link discovered between gene responsible for blood vessel development and ACD in newborns
3. Possible mechanism for link between diabetes and Alzheimers disease discovered
4. Scientists switch components in cell circuits: Possible new technology, therapy
5. Possible new cell type found in developing inner ear
6. Possible gene for form of mental retardation, brain development identified
7. Possible cause and treatment for shock uncovered by UC San Diego bioengineers
8. Reproductive Signals Affect Lifespan In Roundworm C. Elegans, Offering Possible Insight Into Human Aging Process
9. UV Rays, Fire And Flame Retardants To Be Reviewed For Possible Listing As Carcinogens, NTP Announces
10. Coffee Without Addiction, Possible New Treatment For Osteoporosis, Wrinkle-Free Cotton, And More
11. Mechanism For Fungal Adherence Found, Possible Key To Disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... (PRWEB) , ... July 01, 2020 , ... ... that it had completed the purchase of Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, ... company’s existing Japanese clinical supply facility located in Kakegawa, the new 60,000-square-foot facility ...
(Date:6/25/2020)... (PRWEB) , ... June 24, 2020 , ... ... cloud-based enterprise software and software-driven clinical data services that accelerate drug development, is ... low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is ...
(Date:6/23/2020)... THE WOODLNDS, Texas (PRWEB) , ... June 23, ... ... in X-ray analytical instrumentation, is pleased to announce the next event in a ... of X-ray scattering. , The TOPIQ series of webinars was developed in response ...
Breaking Biology News(10 mins):
(Date:6/28/2020)... Md. (PRWEB) , ... June 26, 2020 , ... ... trade association representing security solutions providers, today announced its strong opposition to the ... The bill would impose a blanket ban on most federal use of nearly ...
(Date:6/23/2020)... Ariz. (PRWEB) , ... June 22, 2020 , ... ... is now offering an Amniosomes special offer. This includes buy three, get the ... should call (888) 568-6909. , Amniotic derived exosomes, known as exosomes, have been ...
(Date:6/19/2020)... ... June 18, 2020 , ... The Vitaspace ... is to join forces to radically prolong life and find a way (medicine or ... period. This project was supported by various scientists from all over the world, doctors, ...
(Date:6/11/2020)... ... June 09, 2020 , ... ... of the NEON Micro-Tracer Solution, a highly accurate, contact tracing solution ... in the workplace. Contact tracing, a core disease control measure, is a key ...
Breaking Biology Technology:
Cached News: