HOME >> BIOLOGY >> NEWS
Homocysteine: A Possible Risk Factor For Alzheimer's Disease

Scientists at the Universities of Oxford, in the UK, and Bergen, Norway, have found an association between pathologically-confirmed Alzheimer's disease and moderately elevated blood levels of the amino acid, homocysteine. A moderate elevation in blood levels of homocysteine is a known risk factor for heart disease and stroke.

Researchers found that 76 patients in the Oxford Project to Investigate Memory and Ageing (OPTIMA) who had pathologically-confirmed Alzheimer's disease had elevated blood levels of homocysteine and lower blood levels of folate and vitamin B12 (the vitamins which control homocysteine levels) than 108 age-matched control subjects.

These latest findings, which have yet to be published, were reported yesterday (Monday 27 April) in Nijmegen, Netherlands, at the second International Conference on Homocysteine Metabolism. However, the authors of the report, `Hyperhomocysteinemia: an independent risk factor for histopathologically-confirmed Alzheimer's disease - Professor David Smith, Dr R Clarke, Dr K A Jobst, Ms L Sutton, Professor P M Ueland, and Professor H Refsum - stressed that these biochemical changes in the blood could be a consequence, rather than a cause, of Alzheimer's disease, and that further work is required to distinguish between these two interpretations.

In particular, clinical trials over a number of years will be needed to determine if lowering homocysteine levels, by means of dietary supplementation with folic acid and vitamin B12, influences the development of Alzheimer's disease. Individuals should not take extra folic acid without consulting their doctor.

Profesor David Smith, Chairman of the Department of Pharmacology at Oxford and head of OPTIMA, said: `These findings are important because they provide a testable hypothesis that it may be possible to prevent or delay the progression of Alzheimer's disease in a proportion of potential sufferers. Howev
'"/>

Contact: Gill Sanders or Nicky Old
gill.sanders@admin.ox.ac.uk
44 (0)1865 278181
University of Oxford
28-Apr-1998


Page: 1 2

Related biology news :

1. Possible new cure for psoriasis
2. Possible link discovered between gene responsible for blood vessel development and ACD in newborns
3. Possible mechanism for link between diabetes and Alzheimers disease discovered
4. Scientists switch components in cell circuits: Possible new technology, therapy
5. Possible new cell type found in developing inner ear
6. Possible gene for form of mental retardation, brain development identified
7. Possible cause and treatment for shock uncovered by UC San Diego bioengineers
8. Reproductive Signals Affect Lifespan In Roundworm C. Elegans, Offering Possible Insight Into Human Aging Process
9. UV Rays, Fire And Flame Retardants To Be Reviewed For Possible Listing As Carcinogens, NTP Announces
10. Coffee Without Addiction, Possible New Treatment For Osteoporosis, Wrinkle-Free Cotton, And More
11. Mechanism For Fungal Adherence Found, Possible Key To Disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/17/2019)... ... 16, 2019 , ... At nearly eleven years old, Seve, a white Golden ... owner, in the last year or so, he was a little “gimpy” and occasionally ... Echevarria of VCA University Animal Hospital in Dallas, diagnosed him with severe ...
(Date:7/9/2019)... , ... July 09, 2019 , ... ... Tx Genetic Research into its incubator program. The founder and CEO of Tx ... improve the lives of those suffering from epithelial connective tissue disorders. , “We ...
(Date:6/27/2019)... ... June 27, 2019 , ... Lighting designers from integrated design firm ... which honored the designers for creating both engaging and energy efficient lighting systems. , ... an office tower in San Diego, California earned an IES Illumination Award of Merit ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... NEWPORT BEACH, Calif. (PRWEB) , ... May 30, ... ... the future of neurotoxins, is pleased to announce the strategic acquisition of Metabiologics, ... for research. The acquisition provides Object exclusive ownership and commercialization rights to a ...
(Date:5/15/2019)... ... May 15, 2019 , ... Milton Hershey School® has named William ... work within the biomedical industry, where he is changing lives by creating solutions to ... “William Harding epitomizes the vision of our founders – Milton and Catherine Hershey – ...
(Date:5/8/2019)... ... 2019 , ... Standing at 16.2 hands, Atlas is on the large side for a Quarter ... barrel racing, among other activities. When loping around a corner in late 2017, Atlas ... busy horse to only being able to walk. Fortunately Atlas’ owner, Kelly, sought the ...
(Date:5/2/2019)... ... April 30, 2019 , ... ... standard, REPROCELL USA Inc. has demonstrated its ability to provide various services ... aims to enhance customer satisfaction through the effective implementation of its quality ...
Breaking Biology Technology:
Cached News: