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Hopkins Researchers Discover Key Target In Molecular Pathway That Initiates Colon Cancer

t does to c-MYC. It's like a jigsaw puzzle. We have identified individual pieces of the cancer puzzle and now we can begin to put them together to see the whole picture of how they work together to cause cancer," Kinzler says. Colon cancer, among the most common cancers in both men and women, this year will strike more than 131,000 Americans. Some 56,500 individuals will die of it.

In addition to Vogelstein and Kinzler, other research participants included Tong-Chuan He, M.D., Ph.D., Andrew B. Sparks, Ph.D., Carlo Rago, B.S., Heiko Hermeking, Ph.D., Leigh Zawel, Ph.D., Luis T. Da Costa, M.S., and Patrice J. Morin, Ph.D. The study was funded by the National Institutes of Health.


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Contact: Karin Twilde-Sheifer
oncpubaf@welchlink.welch.jhu.edu
(410) 955-1287
Johns Hopkins Medical Institutions
4-Sep-1998


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