HOME >> BIOLOGY >> NEWS
Hopkins is first US institution to obtain powerful genotyping system

Ahead of other U.S. academic institutions, The Johns Hopkins University School of Medicine and its McKusick-Nathans Institute of Genetic Medicine have pooled resources to obtain a commercial system capable of processing hundreds of DNA samples and determining up to 600,000 genotypes a day.

The $1.5 million system, purchased from Illumina Inc. (San Diego, Calif.), has been installed and tested and should be fully operational by September. Part of the shared genetics resources at Johns Hopkins, the system will use both premade panels of known genetic sequences and research-specific panels of genes, designed in-house, to identify genetic changes in DNA samples.

"In addition to offering a lower cost to researchers, our flexibility should set us apart from what is available from companies," says Alan Scott, Ph.D., director of Johns Hopkins' Genetics Resources Core Facility and one of the forces behind getting the new genotyping system. "Quite a few research programs here require genotyping hundreds to thousands of tissue samples, and other researchers may have been reluctant to take on such tasks because the work couldn't be done nearby. Now we'll be able to offer these services right here at Hopkins."

The new system, called "BeadLab" because of the technology it uses, can examine up to 96 different samples and determine more than 100,000 genotypes in a single experiment. A genotype is a description of an individual's sequence of genetic building blocks (A, G, T and C) and can be compared to others' to help scientists identify genes involved in disease.

Most of the human genome's 3 billion building blocks occur in the same order in all humans. But everyone also has occasional substitution of one genetic building block for another. If a particular spot has a common variation (i.e., some people have an "A" instead of the usual "C"), that position is said to have a single nucle
'"/>

Contact: Joanna Downer
jdowner1@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
14-Aug-2003


Page: 1 2 3

Related biology news :

1. Hopkins scientists use blood proteins to detect ovarian cancer
2. Hopkins to found first center for comprehensive study of epigenetics
3. Hopkins scientists overcome main obstacle to making tons of short, drug-like proteins
4. Hopkins Marine Station honored by the American Society for Microbiology
5. Johns Hopkins gene hunters pinpoint new cancer gene target
6. Hopkins researchers identify transplantation antigens among Sioux Indians
7. Hopkins researchers discover how nitric oxide prevents blood vessel inflammation
8. Dr. Robot tested at Hopkins
9. From Hopkins: Children may outgrow peanut allergies
10. OXiGENE announces launch of ophthalmic clinical trial at The Johns Hopkins School of Medicine
11. Hopkins researchers find potential new treatment for children with chronic hepatitis C

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Hopkins first institution obtain powerful genotyping system

(Date:4/22/2014)... in two Minnesota cities demonstrate how communities can ... a ten year program in New England and ... to local conditions. , "Our goal is to ... said program co-leader Latham Stack, of Syntectic International, ... worsened. We help communities move beyond feeling paralyzed ...
(Date:4/21/2014)... is commonly used as a farm soil fertilizer, contains ... from the cows, gut bacteria. The findings, reported in ... American Society for Microbiology, hints that cow manure is ... genes that transfer to bacteria in the soils where ... (AR) genes have already been identified, but the vast ...
(Date:4/21/2014)... are on the decline in the Galpagos. , A new ... indicates numbers of the iconic birds, known for their ... attract mates, have fallen more than 50 percent in less ... is probably due to an unexplained disappearance of sardines from ... at Wake Forest University and the study,s principal investigator. This ...
Breaking Biology News(10 mins):Minnesota projects offer hope and practical help to communities facing more extreme storms 2Cow manure harbors diverse new antibiotic resistance genes 2Cow manure harbors diverse new antibiotic resistance genes 3Lack of breeding threatens blue-footed boobies' survival 2Lack of breeding threatens blue-footed boobies' survival 3
(Date:1/15/2014)... The Pittcon Organizing Committee is pleased to announce that ... an e-Journal and producer of Food Labs Conference ... for the co-location of Food Labs Conference to be held ... registration fee to attend the two-day Food Lab Conference, March ...
(Date:1/15/2014)... 2014 Look inside the new Preferred ... the lab, from fluid handling to instruments to supplies. ... when you order. , Preferred Solutions features a ... the L/S® model for precise flow control and dispensing ...
(Date:1/15/2014)... California , January 15, 2014 Oxford ... today announced the appointment of Thomas C Reynolds MD, PhD ... years, development experience gained in the biotechnology industry, most recently ... am delighted to welcome Tom at this transformative time for ...
(Date:1/15/2014)... This webinar will focus on EMA and ... in biosimilars. , Regulatory frameworks are evolving many countries ... the complex nature of biopharmaceuticals makes the demonstration of ... challenging. Based on the specific aspects of biosimilar drug ...
Breaking Biology Technology:Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2
Cached News: