HOME >> BIOLOGY >> NEWS
Hopkins researchers find potential new treatment for children with chronic hepatitis C

Researchers from the Johns Hopkins Children's Center and five other institutions have found that a drug recently approved for adults with chronic hepatitis C (CHC) also may be a safe and effective treatment for children with the disease. The study is believed to be the first to examine how the drug, peginterferon alfa-2a, affects the young.

The hepatitis C virus (HCV), the leading cause of liver disease in the United States, is responsible for an estimated 10,000 to 12,000 deaths annually. It is spread primarily by contact with blood and blood products. Blood transfusions and the use of shared, unsterilized, or poorly sterilized needles and syringes have been the main causes of the spread of the virus in the U.S. among adults.

Presented today at the Digestive Disease Week conference, the findings could change the way doctors treat children with CHC, according to the study's lead author, Kathleen B. Schwarz, M.D., director of the Division of Gastroenterology and Nutrition at the Children's Center.

"At present, there is no FDA-approved treatment for children 18 years old and younger with the disease. Our results provide a basis for conducting a large-scale, randomized controlled trial to test this new form of interferon alone, or in combination with ribavirin, an antiviral medication, which is the current treatment of choice for adults with CHC," she said. "Such a study will be necessary before the Food and Drug Administration can approve the drug for children."

Some children with CHC have been treated with three shots a week of interferon to increase the amount of the naturally occurring infection fighter. Peginterferon alfa-2a is a new, longer acting version that, when taken weekly, maintains interferon levels in the blood for a longer period of time. The drug also has been shown more effective in adults with CHC than standard interferon.

In the multi-center
'"/>

Contact: Jessica Collins
jcolli31@jhmi.edu
410-516-4570
Johns Hopkins Medical Institutions
19-May-2003


Page: 1 2

Related biology news :

1. Hopkins scientists use blood proteins to detect ovarian cancer
2. Hopkins to found first center for comprehensive study of epigenetics
3. Hopkins scientists overcome main obstacle to making tons of short, drug-like proteins
4. Hopkins Marine Station honored by the American Society for Microbiology
5. Johns Hopkins gene hunters pinpoint new cancer gene target
6. Hopkins researchers identify transplantation antigens among Sioux Indians
7. Hopkins researchers discover how nitric oxide prevents blood vessel inflammation
8. Hopkins is first US institution to obtain powerful genotyping system
9. Dr. Robot tested at Hopkins
10. From Hopkins: Children may outgrow peanut allergies
11. OXiGENE announces launch of ophthalmic clinical trial at The Johns Hopkins School of Medicine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... anticipated to expand at a CAGR of 25.76% during ... diseases is the primary factor for the growth of ... report: https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global ... product, technology, application, and geography. The stem cell market ...
(Date:4/3/2017)...  Data captured by IsoCode, IsoPlexis Corporation,s ... statistically significant association between the potency of ... objective response of cancer patients post-treatment. The ... cancer patients will respond to CAR-T cell ... to improve both pre-infusion potency testing and cell ...
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University (PolyU) ... ground breaking 3D fingerprint minutiae recovery and matching technology, pushing contactless ... use in identification, crime investigation, immigration control, security of access and ... ... A research team led by Dr Ajay Kumar ...
Breaking Biology News(10 mins):
(Date:9/19/2017)... Pleasanton, Calif. and Washington, D.C. (PRWEB) , ... ... ... to delivering rapid care during an biological outbreak is about to be eliminated, ... When asked what makes ExcitePCR’s FireflyDX™ technologies different than other pathogen ...
(Date:9/19/2017)... ... September 19, 2017 , ... Band-LOK, LLC, an orthopedic ... that two new patents have been allowed by the USPTO on the proprietary ... “We continue to explore additional clinically-relevant designs for both the implants and the ...
(Date:9/17/2017)... , ... September 17, 2017 , ... ... the South Korean Ministry of Food and Drug Safety (KMFDS) for an Investigational ... against the Middle East Respiratory Syndrome coronavirus (MERS-CoV). The study in Korea represents ...
(Date:9/14/2017)... ... , ... Boston Strategic Partners, Inc. (BSP), a life-sciences and ... Research (HEOR) and ‘big data’ to provide in-depth analysis of pneumonia patients characteristics, ... trillion with nearly 1/3 spent on hospitalizations. BSP has access to real-world data ...
Breaking Biology Technology:
Cached News: