HOME >> BIOLOGY >> NEWS
How vitamin C prevents cancer--but apples are better

GENEVA, N.Y. -- Writing in the medical journal, The Lancet , scientists from Cornell University and Seoul National University offer a more precise explanation for vitamin C's anti-cancer activity. And they suggest that a natural chemical from apples works even better than vitamin C.

Their report appears in the Jan. 12, 2002, issue of The Lancet , (Vol. 359, No. 9301), the weekly journal for physicians published in London.

C.Y. Lee, Cornell professor of food science and technology, and his South Korean colleagues, Ki Won Lee, Hyong Joo Lee and Kyung-Sun Kang, found that vitamin C blocks the carcinogenic effects of hydrogen peroxide on intercellular communication. Until this finding, the mechanism for vitamin C's inhibitory effects on carcinogenic tumor formation was not understood.

However, the report notes that quercetin, a phytochemical found in apples, has even stronger anticancer activity than vitamin C. (Phytochemicals, such as flavanoids and polyphenols, are plant chemicals that contain protective, disease-preventing compounds.)

"Vitamin C has been considered one of the most important essential nutrients in our diet since the discovery in 1907 that it prevents scurvy," says Lee. "In addition, vitamin C has several important functions in our body for the synthesis of amino acids and collagen, wound healing, metabolism of iron, lipids and cholesterol and others. In particular, vitamin C is a well known anti-oxidant that scavenges free radicals." (An anti-oxidant is one of many chemicals that reduce or prevent oxidation, thus preventing cell and tissue damage from free radicals in the body.) "Vitamin C prevents the inhibition of gap-junction intercellular communication (GJIC) induced by hydrogen peroxide," says Lee. GJIC is essential for maintaining normal cell growth. Inhibition of GJIC is strongly related to the carcinogenic process, especially to tumor promotion. Hydrogen peroxide, a tumor promoter, inhibits GJIC by ch
'"/>

Contact: Linda McCandless
llm23@cornell.edu
315-787-2417
Cornell University News Service
23-Jan-2002


Page: 1 2

Related biology news :

1. Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
2. Chemical derived from vitamin-E shows early promise as cancer drug
3. Folic acid vitamin use by women reaches all-time high, March of Dimes survey finds
4. Alterations in vitamin D receptor gene increase prostate, breast cancer risk
5. Could vitamins raise levels of bad cholesterol? Animal study suggests they might
6. New antioxidants are 100 times more effective than vitamin E
7. Study finds huge variability in vitamin E absorption
8. People with undetermined muscle/bone pain tend to be severely vitamin D deficient
9. Daily vitamins could prevent vision loss among thousands
10. Drug that mimics vitamin D hormone may boost effectiveness of prostate cancer treatment
11. Strategies to boost womens multivitamin use fall short

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/10/2020)... ... July 08, 2020 , ... ... and Gene Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, 2020 • 1:30 ... study, but what is the most effective way to complete one? Will the ...
(Date:7/1/2020)... ... 2020 , ... Catalent, a global leader in clinical supply ... facility in Minakuchi, located in the Shiga prefecture of Japan. , Operating in ... new 60,000-square-foot facility will provide customers with flexible clinical supply solutions, serving both ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... development services, today announced that the company has received ISO9001:2015 certification for ... diagnostics, and research industries. The decision to pursue ISO9001 accreditation demonstrates Kemp’s ...
Breaking Biology News(10 mins):
(Date:8/31/2020)... ... August 29, 2020 , ... ... manufacturing capability in Wuxi, China. The new plant operation will provide the local ... advanced technology. , “This facility will improve the flexibility of our offerings ...
(Date:8/15/2020)... ... August 13, 2020 , ... Inc. magazine ... the most prestigious ranking of the nation’s fastest-growing private companies. The list represents ... dynamic segment—its independent small businesses. Intuit, Zappos, Under Armour, Microsoft, Patagonia, and many ...
(Date:8/12/2020)... ... August 11, 2020 , ... ... firm, is making available for free its new white paper – Simulated ... simulation testing into today’s biologics licensing application (BLA). In response, Modality Solutions ...
(Date:8/7/2020)... ... August 06, 2020 , ... ... industries, announces it has closed on the purchase of greenfield for a new, ... TX and includes over 21 acres in the initial acquisition, with an option ...
Breaking Biology Technology:
Cached News: