Human Genome Sciences announces the discovery of a novel immune stimulant

s recovering from chemotherapy and bone marrow transplantation may often have low levels of antibodies as a result of low numbers of B cells. In such situations antibody deficiency may last from months to years. One potential medical use of BLyS would be to shorten the recovery time for such patients. Another potential use might be to stimulate B cell growth in AIDS patients deficient in B cell production.

Use as a Vaccine Adjuvant
Vaccines work, in part, by inducing the production of antibodies that recognize invading organisms. Used as a vaccine adjuvant, BLyS may enhance the effectiveness of a wide range of vaccine candidates by strengthening the immune response through its ability to stimulate B cell production.

Treatment of B Cell Leukemia and Lymphoma
The discovery of a new growth factor specific for B cells may also lead to new treatments for leukemias and lymphomas that arise from abnormal proliferation of B cells. BLyS interacts with a specific structure on the surface of B cells called a receptor. Drugs that interfere with binding of BLyS to this receptor may kill or at least slow the growth of B cell tumors.

The Discovery of BLyS
BLyS represents the successful application of a new systematic, multi-step approach to drug discovery pioneered by HGS scientists. The first step of this process was to isolate and characterize a virtually complete set of human genes. A task completed at HGS by the end of 1995. The second step was to prepare a subset of human genes, those involved in cell to cell communication for analysis of their potential medical use. Each of these genes is available at HGS as a cDNA capable of producing a full-length protein. The next step in the process was to develop a high throughput system to test the biological function and potential medical utility of each of these proteins. Such a system is now in place at HGS. BLyS, one of the body's signaling molecules was fo

Contact: Kate de Santis
Human Genome Sciences, Inc.

Page: 1 2 3 4

Related biology news :

1. Human chromosome 5 final sequence analysis released to public
2. Humans march to a faster genetic drummer than primates, UC Riverside research says
3. Applied Mathematical Models in Human Physiology
4. Human health risks in space flight focus of research internships
5. Human periodontal ligament stem cells isolated for the first time
6. Organization for Human Brain Mapping 2004 Annual Meeting
7. 20 May AAAS lecture: Computers that Respond to Human Emotion
8. Human brain works heavy statistics learning language
9. New Woods Hole Center for Oceans and Human Health established
10. European Society of Human Reproduction and Embryology conference - June 2004
11. Human genome-wide RNAi library for biotech and pharma research

Post Your Comments:
(Date:9/2/2015)... Sept. 2, 2015 About hand geometry biometrics ... banks, government organizations, telecommunication and hospitals as well as ... badges, and numeric keypads are used to prevent unauthorised ... palm and fingers of an individual, width of the ... with infrared light and reflectors can be used for ...
(Date:8/31/2015)... August 31, 2015 Growing need ... in government digitization projects to drive India ... published TechSci Research report, " India Biometrics Market Forecast & ... is projected to grow at a CAGR of over ... anticipated on account of extensive use of biometric technology in ...
(Date:8/25/2015)... LAKE CITY and BELLEVUE, Wash. ... global leader in advanced robotic systems, announced today it ... robotic unmanned ground vehicle (UGV), at the National Tactical ... City.  The Guardian S is the ... the culmination of years of research and in-field trials ...
Breaking Biology News(10 mins):Global Hand Geometry Biometrics Market 2015-2019 2Global Hand Geometry Biometrics Market 2015-2019 3India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 2India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 3Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3
(Date:10/1/2015)... Oct. 1, 2015  xG Health Solutions, a ... xghealth.com, a new platform for communication and collaboration ... health systems and health plans improve the quality ... xG Health solutions, products and educational resources. ... and, as clinicians, we know the process of ...
(Date:10/1/2015)... ... October 01, 2015 , ... USDM Life Sciences , a ... it was selected by FDA to develop and implement a program for the Drug ... with FDA on this critical initiative for the life science and healthcare industries,” said ...
(Date:9/30/2015)... ... 2015 , ... Cambridge Semantics, the leading provider ... joined the Google for Work Partner Program as a Google Cloud Platform Technology ... dynamic infrastructures and this relationship allows the company to extend its robust smart ...
(Date:9/30/2015)... TORONTO , Sept. 30, 2015 Generex ... that it has entered into a non-binding Letter of ... www.rapid123.com ), a Florida company ... The LOI contemplates that Generex will acquire ... a purchase price of US$15,000,000 to be paid in ...
Breaking Biology Technology:xG Health Solutions Launches New Platform for Hospitals, Clinics and Health Plans 2USDM Life Sciences Chosen by FDA to Assess Pharmaceutical Readiness for Drug Supply Chain Security Act 2Cambridge Semantics Joins ‘Google for Work Partner Program’ as Cloud Platform Partner 2Generex Announces Agreement to Acquire Equity Interest in Hema Diagnostic Systems 2Generex Announces Agreement to Acquire Equity Interest in Hema Diagnostic Systems 3Generex Announces Agreement to Acquire Equity Interest in Hema Diagnostic Systems 4Generex Announces Agreement to Acquire Equity Interest in Hema Diagnostic Systems 5Generex Announces Agreement to Acquire Equity Interest in Hema Diagnostic Systems 6
Cached News: