HOME >> BIOLOGY >> NEWS
Identifying individuals at risk for Alzheimer's disease

ARTICLE: "APOE-e4 and APOE -491A polymorphisms in individuals with subjective memory loss."

AUTHORS: SM Laws, RM Clarnette, K Taddei, G Martins, A Paton, J Hallmayer, OP Almeida, DM Groth, SE Gandy, H Frstl and RN Martins

Sir James McCusker Alzheimer's Disease Research Unit, Department of Surgery, University of Western Australia, Hollywood Private Hospital, Perth, Western Australia; Department of Psychiatry and Behavioural Science, Stanford University, Palo Alto, CA, USA; Department of Psychiatry and Behavioural Science, University of Western Australia, QE11 Medical Centre, Perth, Western Australia; School of Biomedical Science, Curtin University of Technology, Bentley, Western Australia; Alzheimer Research Program, New York University, NS Kline Institute, Orangeburg, New York, USA; Department of Psychiatry and Psychotherapy, Technical University of Munich, Munich, Germany.

Rational approaches to drug discovery for Alzheimer's disease are moving rapidly worldwide. Unfortunately, "prevention" is much more likely to be a successful strategy, rather than trying to re-create a severely damaged, demented brain. Genetic markers such as those studied by Martins and colleagues at the McCusker Alzheimer Foundation, University of Western Australia and Hollywood Private Hospital hold promise for guiding clinical trials: these markers may allow us to winnow down the general population to a more manageable pool of individuals with relatively higher risk for Alzheimer's. In this project, Martins and colleagues developed a set of tools for identifying such enriched populations. This work may impact on future clinical trials of anti-Alzheimer drugs.


'"/>

Contact: Frank Sissingh
molecularpsychiatry@mednet.ucla.edu
310-206-6739
Molecular Psychiatry
3-Sep-2002


Page: 1

Related biology news :

1. Identifying tick genes could halt disease, bioterrorism threat
2. Identifying cancer genes Will it really lead to better treatment?
3. Identifying novel small RNAs
4. Breakthrough in genomic technology: Identifying the biologically relevant parts of the human genome
5. Weizmann Institute scientists report why taste and smell differ among individuals
6. Brains of outgoing people react more to happy faces than those of shy individuals
7. Drug breaks for HIV-infected individuals may put certain immune cells at risk
8. Fundamental structural differences discovered in brains of autistic individuals
9. Next-generation AIDS vaccine for healthy individuals being tested for safety, tolerability at UC Davis
10. Kaposis sarcoma-associated herpesvirus causes no negative health effects in hiv-negative individuals, find University of Pittsburgh researchers
11. Electrophysiological differences of individuals at high risk for alcoholism

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2019)... ... , ... In the wake of the success of IBBL’s ... biobanks was launched in July 2018, in an agreement between IBBL, the International ... Biotech Association (BBCMBA). The one-year pilot programme offered two testing schemes: ‘DNA quantification ...
(Date:3/27/2019)... ... March 27, 2019 , ... NDA Partners Chief Executive Officer ... Health & Pharma Biotechnology Award as the Best Life Sciences Management & Contract ... individuals and companies whose accomplishments have proved evidence of extensive expertise and skills, ...
(Date:3/25/2019)... , ... March 25, 2019 , ... ... Visikol, a contract research organisation focused on advancing drug discovery, have announced a ... imaging. , Tissue clearing methods, which are essential to get a better view ...
Breaking Biology News(10 mins):
(Date:4/12/2019)... ... April 12, 2019 , ... ... neurotechnology and will educate about innovative tools and devices being used to enhance ... for more information. , This segment of Advancements will focus on Sound for ...
(Date:4/9/2019)... , ... April 09, 2019 , ... The American ... members of the Society's leadership team, including a new addition to the presidential line ... of their peers to join the Society's leadership team for a three-year term (2019-2021). ...
(Date:4/4/2019)... ... , ... LeadingBiotech, an exclusive event series bringing biopharma CEOs ... CEO conference to be held May 28-29, 2019 at Boston’s Four Seasons Hotel. ... and discussions from past, present and future change-makers. , LeadingBiotech, formerly ...
(Date:3/23/2019)... ... 2019 , ... uBiome has awarded microbiome research support in ... Nnamdi Azikiwe University in Anambra State, Nigeria led by Dr. Kingsley C. Anukam, ... Medical Laboratory Sciences and Deputy Provost, College of Health Sciences. The study hopes ...
Breaking Biology Technology:
Cached News: