HOME >> BIOLOGY >> NEWS
Imaging technique may help in confirming, monitoring treatment of malignant brain tumors

In what is believed to be a first-of-its-kind study, Johns Hopkins researchers have used magnetic resonance imaging (MRI) to measure sodium concentrations in the cells of malignant brain tumors. Because growth of such cancers are linked to elevated sodium levels, an easy way to measure them could improve diagnosis and treatment monitoring. The study is published in the May 1 edition of Radiology.

"Determining precise sodium concentrations has been a problem, but MRI can do it at the same time it identifies possible malignant lesions," says Ronald Ouwerkerk, Ph.D., instructor of radiology at the Johns Hopkins Department of Radiology, MRI Research Division. Using proton MRI after injecting contrast agents to enhance areas containing many small blood vessels, the researchers found 50 percent more sodium in lesions that turned out to be malignant tumors than in normal brain tissue.

"Using MRI noninvasively in a single examination to get information about tumor metabolism and physiology improves identification of tumor malignancy and is a big step forward," says Ouwerkerk.

In the Hopkins study, 20 patients with brain malignancies confirmed by biopsy and nine subjects with no brain tumors underwent sodium MRI. Sodium concentrations were determined in malignant tumors, gray brain matter, white brain matter, cerebrospinal fluid and vitreou s humor (fluid within the eye). The image intensities in the sodium images were compared with the signals from a sample with known sodium content. The special scan method the researchers use for three-dimensional sodium MRI makes it possible to directly calculate sodium concentrations.

The researchers found sodium concentrations in cancer cells were elevated by an average of 50 percent compared to the other noncancerous tissues or those tissues in subjects with no tumors.

Elevated sodium, as an indicator of cancer, may be due to several factors. Among them are angiogenesis, development o
'"/>

Contact: Gary Stephenson
gstephenson@jhmi.edu
410-955-5384
Johns Hopkins Medical Institutions
1-May-2003


Page: 1 2

Related biology news :

1. Imaging the healing heart
2. Imaging study shows brain maturing
3. Imaging the brain solving problems through insight
4. Imaging technique reveals new structure in retinal cells
5. Imaging technique discovered at Stanford monitors cancer cell proliferation
6. Imaging study provides new information on how the brain processes sounds of different tones
7. Imaging apparatus characterizes drops in dirty laboratory environments
8. New Imaging Technique Pinpoints Dead Heart Muscle
9. Imaging Studies Illuminate Brains Response To Cocaine
10. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
11. New technique helps scientists reveal interactions between genes and drugs

Post Your Comments:
(Date:10/16/2014)... new synthesis of recent research findings to inform their ... two states. , The Ecology and Management of ... Synthesis of the Relevant Biophysical Science and Implications for ... the U.S. Forest Service,s Pacific Northwest Research Station, is ... a synthesis of the large body of scientific information ...
(Date:10/16/2014)... , October 16, 2014 NXT-ID, Inc. ... the "Company"), a biometric authentication company focused on the ... leading edge technologies including Wocket™, the Smart Wallet, at ... Conferenece. FiRe is a leading global conference on the ... Hosted by Mark Anderson , founder and publisher ...
(Date:10/15/2014)... an unexpected extent. The outbreak does not follow the ... a new disease dynamic in regions, where it has ... National Academy of Sciences Leopoldina, acatech – the German ... the German Academies of Sciences and Humanities have presented ... the statement the academies call for the following consequences ...
Breaking Biology News(10 mins):New report synthesizes best available science on management of moist mixed-conifer forests 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5
(Date:10/18/2014)... The “Human Insulin Market- by Product Type, [Human ... Insulin (Rapid Acting, Long Acting, Premixed)], by Brand ... Forecast to 2018” provides a detailed overview of ... trends, and strategies impacting the global human insulin ... the revenue and share analysis. , The global ...
(Date:10/18/2014)... The report "1,6-Hexanediol Market by Application and By ... the global market on the basis of its ... such as the key drivers, current trends and ... 81 Market Data Tables and 29 Figures spread ... Market by Application and by Geography - Trends ...
(Date:10/18/2014)... Asia-Pacific hardware encryption display market report defines and segments ... of revenue. This market was valued $5,154.0 million in ... 2018, at a CAGR of 58.4% from 2013 to ... hardware encryption market report, to get an idea of ... of the segmentation of the market, and is supported ...
(Date:10/18/2014)... The Asian Electronic Medical Record (EMR) market ... analysis and forecast of revenue. The electronic medical record market ... million by 2018, at a CAGR of 9.4% from 2013 ... Electronic Medical Record (EMR) market, to get an idea of ... the segmentation of the market in the same region, and ...
Breaking Biology Technology:Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 2Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 3Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 51,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 3The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 2The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 3The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 4The Asian Electronic Medical Record (EMR) market is estimated to grow to $2,328.0 million by 2018 - New Report by MicroMarket Monitor 5
Cached News: