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Imaging technique may help in confirming, monitoring treatment of malignant brain tumors

f new micro blood vessels to feed the tumor and cell growth, both of which cause increased sodium. Energy depletion and the death of normal cells also lead to a massive increases in cell sodium content. However, in malignant tumors, there is an increase in sodium in cells that are not energy deprived or dying, but are rapidly dividing. The signaling mechanism that "turns on" cells to divide rapidly in cancer leads to an influx of sodium into the cell.


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Contact: Gary Stephenson
gstephenson@jhmi.edu
410-955-5384
Johns Hopkins Medical Institutions
1-May-2003


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