HOME >> BIOLOGY >> NEWS
Imaging the healing heart

Being able to visualize the healing of damaged tissue after a heart attack is vital for obtaining appropriate therapies for heart patients. Albert Sinusas and colleagues, from Yale University School of Medicine, have now developed a noninvasive method for imaging this process.

Following a heart attack, new blood vessels are formed during the healing and remodeling process. In order to encourage healing, therapies for post-heart attack recovery have focused on enhancing factors that induce new blood vessel growth, but evaluation of the efficacy of these strategies is difficult due to the lack of accurate means to measure the thera-peutic effect. Now, Sinusas and colleagues, by radioactively labeling a protein that is present specifically in newly developing blood vessels (a protein called avB3 integrin), have found they could actually track the process of blood vessel growth in the hearts of rat and canine heart-attack models using standard tomography methods.

By taking multiple, timed images of the heart, the authors could detect changes in the presence of the marker-protein in the areas damaged during the heart attack. They found that this marker specifically increased in these damaged areas as new blood vessels developed, and allowed clear view of changes in the damaged area over time. Since this method is both non-invasive and uses standard imaging technology, it is an ideal new tool for monitoring changes of damaged areas in patients after a heart attack and during therapeutic trials of potential drugs to enhance such healing.


'"/>

Contact: Laurie Goodman
press_releases@the-jci.org
212-342-4159
Journal of Clinical Investigation
15-Jun-2004


Page: 1

Related biology news :

1. Imaging study shows brain maturing
2. Imaging the brain solving problems through insight
3. Imaging technique reveals new structure in retinal cells
4. Imaging technique discovered at Stanford monitors cancer cell proliferation
5. Imaging technique may help in confirming, monitoring treatment of malignant brain tumors
6. Imaging study provides new information on how the brain processes sounds of different tones
7. Imaging apparatus characterizes drops in dirty laboratory environments
8. New Imaging Technique Pinpoints Dead Heart Muscle
9. Imaging Studies Illuminate Brains Response To Cocaine
10. Bone marrow cells routinely help with wound healing
11. Social benefits of wound healing may not make any difference in animals with multiple partners

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/1/2016)... June 1, 2016 Favorable Government ... Administration and Criminal Identification to Boost Global Biometrics System ... released TechSci Research report, " Global Biometrics Market ... Forecast and Opportunities, 2011 - 2021", the global biometrics ... 2021, on account of growing security concerns across various ...
(Date:5/16/2016)... NEW YORK , May 16, 2016   ... authentication solutions, today announced the opening of an IoT ... to strengthen and expand the development of embedded ... provides an unprecedented level of convenience and security with ... to authenticate one,s identity aside from DNA. EyeLock,s platform ...
(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... regulatory and technical consulting, provides a free webinar on Performing Quality ... 13, 2016 at 12pm CT at no charge. , Incomplete investigations are still ...
(Date:6/22/2016)... June 22, 2016 Cell Applications, Inc. ... them to produce up to one billion human ... within one week. These high-quality, consistent stem cells ... cells and spend more time doing meaningful, relevant ... proprietary, high-volume manufacturing process that produces affordable, reliable ...
(Date:6/22/2016)... Philadelphia, PA (PRWEB) , ... June 22, 2016 ... ... the University City Science Center’s Port business incubator and current participant in the ... therapy and treatment for cancer patients. , Quantitative Radiology Solutions helps physicians ...
Breaking Biology Technology:
Cached News: