Inability to pump oxygen during exercise could pinpoint early heart problems

Mildly elevated blood pressure affecting millions of Americans could lead to heart pumping disorders if left untreated. A new Johns Hopkins study indicates that the amount of oxygen that can be circulated throughout the body during each heart beat while exercising could reveal to doctors early signs of heart trouble in this population.

The research, to be presented Oct. 17 at the annual meeting of the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) in Kansas City, should help physicians better follow patients with problems of the left ventricle, or main pumping chamber of the heart, by studying so-called oxygen pulse.

During exercise, lungs take in air and transfer oxygen to the blood, which is then pumped by the heart to the muscles that need it. Oxygen pulse is the amount of oxygen put through this process with each heart beat, and is a measure of cardiovascular efficiency.

Researchers studied 99 adults (44 men and 55 women) ages 55 to 75 who had mild hypertension but were otherwise healthy. The participants' blood pressures ranged from 130 mmHg to 159 mmHg systolic (the upper number) and 85 mmHg to 99 mmHg diastolic (the lower number). These levels are also known as "prehypertension" or "Stage I hypertension."

The Hopkins team measured the adults' heart size and performance at rest through traditional echocardiograms (or ultrasound), and tissue Doppler imaging, a newer ultrasound method that examines the functioning of the heart's walls. Next, they compared those results with the participants' heart performance during exercise while the adults walked on a treadmill. The scientists measured oxygen usage during the exercise portion by having the subject breathe through a mouthpiece attached to a valve that measures how much oxygen is used during the test.

Normally there is a sharp increase in oxygen pulse during the first few minutes of exercise. This rise continues with exercise, an

Contact: Karen Blum
Johns Hopkins Medical Institutions

Page: 1 2

Related biology news :

1. Jefferson Scientists Find Evidence Of Potentially Infectious HIV In Semen, Despite Inability To Detect Active Virus In Blood
2. Researchers discover how worms noses sense oxygen
3. Researchers show absence of key oxygen-sensing molecule leads to developmental defects
4. Ultra-low oxygen could have triggered die-offs, spurred bird breathing system
5. Heart may heal with help from oxygen-sensitive genes, new study suggests
6. Cells ability to live without oxygen give clues for treating major diseases
7. U-Iowa scientists gain insight on how enzyme uses oxygen to produce useful chemicals
8. Topical oxygen helps hard-to-heal wounds heal faster and better
9. Too much oxygen on the cell biology bench? New study suggests so
10. Tibetans retain resistance to the oxygen-deficient disorder hypoxia regardless of altitude
11. Study shows deoxygenating ballast water can prevent invasive species and ship corrosion

Post Your Comments:

(Date:5/9/2016)... UAE, May 9, 2016 Elevay ... comes to expanding freedom for high net worth professionals ... in today,s globally connected world, there is still no ... could ever duplicate sealing your deal with a firm ... passports by taking advantage of citizenship via investment programs ...
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted to ... of 2015 The gross margin was 49% (27) ... operating margin was 40% (-13) Earnings per share rose ... was SEK 249.9 M (21.2) , Outlook   ... The operating margin for 2016 is estimated to exceed ...
(Date:4/19/2016)... The new GEZE SecuLogic access ... "all-in-one" system solution for all door components. It can ... door interface with integration authorization management system, and thus ... minimal dimensions of the access control and the optimum ... offer considerable freedom of design with regard to the ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... ... its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced ... this eBook by providing practical tips, tools, and strategies for clinical researchers. , ...
(Date:6/23/2016)... Mass. , June 23, 2016   ... development of novel compounds designed to target cancer ... napabucasin, has been granted Orphan Drug Designation from ... the treatment of gastric cancer, including gastroesophageal junction ... stemness inhibitor designed to inhibit cancer stemness pathways ...
(Date:6/23/2016)... A person commits a crime, and the detective ... the criminal down. An outbreak of foodborne illness ... (FDA) uses DNA evidence to track down the bacteria that ... It,s not. The FDA has increasingly used a complex, cutting-edge ... illnesses. Put as simply as possible, whole genome sequencing is ...
(Date:6/23/2016)... ... June 23, 2016 , ... Charm ... Mold) microbial test has received AOAC Research Institute approval 061601. , “This is ... last year,” stated Bob Salter, Vice President of Regulatory and Industrial Affairs. “The ...
Breaking Biology Technology:
Cached News: