HOME >> BIOLOGY >> NEWS
Interferons effective against smallpox

BALTIMORE March 11, 2003 Proteins produced by the immune system, known as interferons, may be an effective treatment for smallpox, say researchers today at the American Society for Microbiologys Biodefense Research Meeting.

Certain cytokines, particularly interferons, are well known for their antiviral effects in various virus infections, says Ge Liu of Advanced Biosystems, Inc. in Manassas, Virginia, a lead researcher in the study, in collaboration with scientists from the Southern Research Institute in Frederick, Maryland, and George Mason University.

The researchers tested the ability of a number of interferons and interleukins, administered intranasally, to protect mice from a lethal infection with vaccinia virus, a close relative to the smallpox virus that is often used in mice to test potential smallpox treatments. Mice treated with interferons alpha and gamma had survival rates over 95 percent, compared to control groups in which no mice survived.

Intranasal administration of interferon alpha and interferon gamma provides nearly full protection against respiratory vaccinia virus infection in mice, says Liu. Therefore, our results have implications in the utilization of interferon as a prophylactic tool in a scenario of aerosol orthopoxvirus infection.

The American Society for Microbiology (ASM) is the largest single life science society, composed of over 42,000 scientists, teachers, physicians, and health professionals. Its mission is to promote research and training in the microbiological sciences and to assist communication between scientists, policymakers, and the public to improve health, economic well being, and the environment.


'"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
11-Mar-2003


Page: 1

Related biology news :

1. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
2. Endurance exercise found to be equally effective as diuretics in improving cardiac health
3. Purdue yeast makes ethanol from agricultural waste more effectively
4. Scientists learn how adjuvant makes vaccines effective
5. Super-effective jumping gene created
6. Drug combo effective in advanced breast cancer
7. Data show investigational antibiotic safe, effective in preventing travelers diarrhea
8. Mexican farmers effectively cultivate phenotypic diversity in maize
9. Newer drugs more effective at curing strep throat than penicillin
10. Researchers show chronic sinusitis is immune disorder; antifungal medicine effective treatment
11. Ribozyme package effective against hepatitis B virus

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute for ... Cell Explorer: a one-of-a-kind portal and dynamic digital window ... imaging data, the first application of deep learning to ... stem cell lines and a growing suite of powerful ... for these and future publicly available resources created and ...
(Date:4/4/2017)... NEW YORK , April 4, 2017   ... solutions, today announced that the United States Patent and ... The patent broadly covers the linking of an iris ... the same transaction) and represents the company,s 45 th ... our latest patent is very timely given the multi-modal ...
Breaking Biology News(10 mins):
(Date:9/21/2017)... ... September 21, 2017 , ... When a ... the response was swift and efficient thanks to the continuing efforts of members ... up of more than 50 stakeholders, including officials from area counties and cities, ...
(Date:9/20/2017)... ... 20, 2017 , ... Cybrexa Therapeutics , a start-up ... role of chief scientific officer. In this role, Dr. Paralkar will lead the ... CEO, Per Hellsund. , “I was impressed with Cybrexa’s revolutionary technology and excellent ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... the effects of exoskeleton-assisted walking on gait parameters and neuromuscular activity in ... adaptations during a robotic powered exoskeleton assisted walking session" (doi:10.1080.10790268.2017.1314900) was epublished ...
(Date:9/19/2017)... , ... September 19, 2017 , ... ... accurately automates the most dangerous step of sample prep for metals digestion—the addition ... provide automation at an affordable price. The system is ideal for any laboratory ...
Breaking Biology Technology:
Cached News: