HOME >> BIOLOGY >> NEWS
Iron-binding compounds produced by marine bacteria have important implications for marine microbial ecology

(Santa Barbara, Calif.) Structures of newly-discovered siderophores (the iron-carrying molecules secreted by bacteria to facilitate iron acquisition) described in the February 18 issue of Science by researchers at the University of California, Santa Barbara and other institutions, shed light on how marine bacteria acquire iron and raise provocative questions about the evolution of iron uptake by marine bacteria.

All bacteria need iron to grow, and in the ocean there is very little iron, explained Alison Butler, professor of chemistry and biochemistry at UC, Santa Barbara and co-author of the article. "We wanted to know what molecular mechanisms control iron uptake," said Butler.

The article, "Self-Assembling Amphiphilic Siderophores from Marine Bacteria," describes the structures of the marinobactin and aquachelin siderophores which have polar peptidic head groups and hydrophobic fatty acid tails, explained Butler. "They have a hydrophobic portion and a hydrophilic portion," she said. "Like soap, they have a portion that dissolves in water and part that dissolves in grease."

The marinobactins are present as micelles (aggregations of molecules) and upon addition of iron, the micelles undergo a spontaneous phase change to form vesicles (bladder-like spheres).

When iron is added, it binds to the peptidic head, and then vesicles are formed.

"The transformation from micelle to vesicle upon iron coordination is the first example, to our knowledge, of such a metal-induced phase change in a biologically produced compound," said the authors. "The presence of this metal-induced switch raises questions about the physiological role for this transformation."

The authors were struck by the fact that different bacteria had the same 'strategy' for acquiring the iron. They state: "It is quite striking that these siderophores, whose distinctive properties hint at the possibility of a novel iron acquisition mechanism, are made by strains from two differen
'"/>

Contact: Gail Brown
gbrown@instadv.ucsb.edu
805-893-7220
University of California - Santa Barbara
16-Feb-2000


Page: 1 2 3

Related biology news :

1. Iron-binding compounds decrease body odor
2. Scientists identify compounds that mimic calorie restriction
3. New, non-radioactive screen for antimalarial compounds
4. Three molecular-targeted compounds show promise against cancers
5. Emory scientists find anti-tumor compounds in magnolia cones
6. Mouse model links alcohol intake to marijuana-like brain compounds
7. New evidence for organic compounds in deep space
8. Researchers identify compounds that might help in spinal cord repair
9. Selected estrogen compounds modify risks of vein clotting, a response to hormone replacement theraphy
10. Vitamin C produces gene-damaging compounds, test-tube study in Science reports
11. Labeling of active compounds in ginseng varies from actual content

Post Your Comments:
(Date:8/10/2015)... , August 10, 2015 ... Eye Tracking Technology for more than two decades, announces ... for integration into all consumer display formats. The SMI ... integration of eye tracking into consumer tablets, laptops, desktop ... smart glasses. Omnivision,s leading sensor technology contributes to the ...
(Date:8/6/2015)... CITY, Calif. , Aug. 6, 2015 /PRNewswire/ ... Valley) will visit Crossmatch ™ to learn ... networks and protect data. Crossmatch is a world ... whose technologies and expertise are helping federal agencies ... efficiency and security.   "The vast ...
(Date:8/6/2015)... 6, 2015 Synaptics Inc. (NASDAQ: ... solutions, today announced collaboration with Microsoft on biometric ... Microsoft leveraged Synaptics, deep expertise in human interface ... Through stringent testing, Synaptics, advanced image ... Microsoft,s Precision TouchPad (PTP) specification empowering OEMs with ...
Breaking Biology News(10 mins):SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Rep. Honda to Visit Crossmatch in Redwood City 2Synaptics Chosen for Human Interface Co-Development on Windows 10 2
(Date:9/1/2015)... ... ... A new host-based therapy for Ebola, anthrax and other ... and its collaborators. The discovery has the potential to speed to market treatments ... by Scientific Reports, an open access research journal from the publishers of Nature. ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... release of a groundbreaking new version of its flagship DNA design platform, which ... down complex DNA sequences into numerous genetic parts, which in turn can be ...
(Date:8/31/2015)... ... August 31, 2015 , ... The Global Supply Chain ... management and resiliency practitioners with luminaries and thought leaders to advance the professional ... for their innovations and performance excellence. At that time its principle sponsor, ...
(Date:8/31/2015)... ... August 31, 2015 , ... In recent years, biodegradable ... as low carbon footprints and compostability. These properties can help in limiting the ... the basis of applications, the market for biodegradable plastics can be broadly segmented ...
Breaking Biology Technology:Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 2Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 3Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 4GenoCAD Releases Combinatorial Design Tool to Optimize Protein Expression and Streamline DNA Synthesis Orders 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 3Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 2Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 3Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 4Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 5
Cached News: