HOME >> BIOLOGY >> NEWS
Iron-binding compounds produced by marine bacteria have important implications for marine microbial ecology

(Santa Barbara, Calif.) Structures of newly-discovered siderophores (the iron-carrying molecules secreted by bacteria to facilitate iron acquisition) described in the February 18 issue of Science by researchers at the University of California, Santa Barbara and other institutions, shed light on how marine bacteria acquire iron and raise provocative questions about the evolution of iron uptake by marine bacteria.

All bacteria need iron to grow, and in the ocean there is very little iron, explained Alison Butler, professor of chemistry and biochemistry at UC, Santa Barbara and co-author of the article. "We wanted to know what molecular mechanisms control iron uptake," said Butler.

The article, "Self-Assembling Amphiphilic Siderophores from Marine Bacteria," describes the structures of the marinobactin and aquachelin siderophores which have polar peptidic head groups and hydrophobic fatty acid tails, explained Butler. "They have a hydrophobic portion and a hydrophilic portion," she said. "Like soap, they have a portion that dissolves in water and part that dissolves in grease."

The marinobactins are present as micelles (aggregations of molecules) and upon addition of iron, the micelles undergo a spontaneous phase change to form vesicles (bladder-like spheres).

When iron is added, it binds to the peptidic head, and then vesicles are formed.

"The transformation from micelle to vesicle upon iron coordination is the first example, to our knowledge, of such a metal-induced phase change in a biologically produced compound," said the authors. "The presence of this metal-induced switch raises questions about the physiological role for this transformation."

The authors were struck by the fact that different bacteria had the same 'strategy' for acquiring the iron. They state: "It is quite striking that these siderophores, whose distinctive properties hint at the possibility of a novel iron acquisition mechanism, are made by strains from two differen
'"/>

Contact: Gail Brown
gbrown@instadv.ucsb.edu
805-893-7220
University of California - Santa Barbara
16-Feb-2000


Page: 1 2 3

Related biology news :

1. Iron-binding compounds decrease body odor
2. Scientists identify compounds that mimic calorie restriction
3. New, non-radioactive screen for antimalarial compounds
4. Three molecular-targeted compounds show promise against cancers
5. Emory scientists find anti-tumor compounds in magnolia cones
6. Mouse model links alcohol intake to marijuana-like brain compounds
7. New evidence for organic compounds in deep space
8. Researchers identify compounds that might help in spinal cord repair
9. Selected estrogen compounds modify risks of vein clotting, a response to hormone replacement theraphy
10. Vitamin C produces gene-damaging compounds, test-tube study in Science reports
11. Labeling of active compounds in ginseng varies from actual content

Post Your Comments:
(Date:2/12/2015)...   MedNet Solutions , a global life ... systems, has recently bolstered its iMedNet™ ... iMedNet as the eClinical solution of ... consultants.  Building on the Program,s existing benefits (including ... co-marketing opportunities), MedNet,s new and improved program provides ...
(Date:2/11/2015)... February 11, 2015 ... "Access Control Market by Product (Cards and Readers, Biometrics, ... Defense, Government, Industrial, Healthcare, Education) and By Geography - Global ... MarketsandMarkets, the Access Control Market is expected ... at a CAGR of 10.6% between 2014 ...
(Date:2/9/2015)... 9, 2015  Lintec of America recently announced an ... nanotube (CNT) macrostructures, including sheets, yarns and ribbons, developed ... Leveraging the vast industrial resources of the global ... , Lintec of America is forming the Nano-Science and ... , focusing on scaling up the manufacturing and commercialization ...
Breaking Biology News(10 mins):MedNet Solutions Announces Key Enhancements To Its iMedNet Partner Program 2Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 2Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 3Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 4
(Date:2/26/2015)... , Feb. 26, 2015  Dyadic International, Inc. ... patented and proprietary technologies are used to develop, ... the bioenergy, bio-based chemical, biopharmaceutical and industrial enzyme ... financial results for year ending December 31, 2014 ... and will host a conference call that day ...
(Date:2/26/2015)... Ceres, Inc . today announced that ... In attaining Gold Level membership, Ceres has been recognized ... in delivering Ceres, Persephone genome visualization software and for ... Originally developed for in-house use by Ceres, the Persephone ... of massive amounts of genetic data, from a chromosome ...
(Date:2/26/2015)... 2015  Epic Sciences announced today that President and ... the 35th Annual Cowen and Company Health Care Conference ... Room, 3rd Floor. The conference will be held at ... Epic is developing diagnostic tests of high clinical ... changes that occur during the course of cancer treatments. ...
(Date:2/26/2015)... (NASDAQ: ONCE ) announced today that members ... and Company Health Care Conference on Wednesday, March 4, ... Copley Place. To access the live webcast ... please visit the "Upcoming Events" section within the "News ... www.sparktx.com .  A replay of the webcast will ...
Breaking Biology Technology:Dyadic International To Announce Fourth Quarter 2014 Financial Results And Host Conference Call On Wednesday, March 11, 2015 2Dyadic International To Announce Fourth Quarter 2014 Financial Results And Host Conference Call On Wednesday, March 11, 2015 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4Epic Sciences to Present at 35th Annual Cowen and Company Health Care Conference 2Spark Therapeutics to Participate in the 35th Annual Cowen and Company Health Care Conference 2
Cached News: