HOME >> BIOLOGY >> NEWS
Iron-binding compounds produced by marine bacteria have important implications for marine microbial ecology

(Santa Barbara, Calif.) Structures of newly-discovered siderophores (the iron-carrying molecules secreted by bacteria to facilitate iron acquisition) described in the February 18 issue of Science by researchers at the University of California, Santa Barbara and other institutions, shed light on how marine bacteria acquire iron and raise provocative questions about the evolution of iron uptake by marine bacteria.

All bacteria need iron to grow, and in the ocean there is very little iron, explained Alison Butler, professor of chemistry and biochemistry at UC, Santa Barbara and co-author of the article. "We wanted to know what molecular mechanisms control iron uptake," said Butler.

The article, "Self-Assembling Amphiphilic Siderophores from Marine Bacteria," describes the structures of the marinobactin and aquachelin siderophores which have polar peptidic head groups and hydrophobic fatty acid tails, explained Butler. "They have a hydrophobic portion and a hydrophilic portion," she said. "Like soap, they have a portion that dissolves in water and part that dissolves in grease."

The marinobactins are present as micelles (aggregations of molecules) and upon addition of iron, the micelles undergo a spontaneous phase change to form vesicles (bladder-like spheres).

When iron is added, it binds to the peptidic head, and then vesicles are formed.

"The transformation from micelle to vesicle upon iron coordination is the first example, to our knowledge, of such a metal-induced phase change in a biologically produced compound," said the authors. "The presence of this metal-induced switch raises questions about the physiological role for this transformation."

The authors were struck by the fact that different bacteria had the same 'strategy' for acquiring the iron. They state: "It is quite striking that these siderophores, whose distinctive properties hint at the possibility of a novel iron acquisition mechanism, are made by strains from two differen
'"/>

Contact: Gail Brown
gbrown@instadv.ucsb.edu
805-893-7220
University of California - Santa Barbara
16-Feb-2000


Page: 1 2 3

Related biology news :

1. Iron-binding compounds decrease body odor
2. Scientists identify compounds that mimic calorie restriction
3. New, non-radioactive screen for antimalarial compounds
4. Three molecular-targeted compounds show promise against cancers
5. Emory scientists find anti-tumor compounds in magnolia cones
6. Mouse model links alcohol intake to marijuana-like brain compounds
7. New evidence for organic compounds in deep space
8. Researchers identify compounds that might help in spinal cord repair
9. Selected estrogen compounds modify risks of vein clotting, a response to hormone replacement theraphy
10. Vitamin C produces gene-damaging compounds, test-tube study in Science reports
11. Labeling of active compounds in ginseng varies from actual content

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/6/2017)... 2017  Privately-held CalciMedica, Inc., announced that it ... of a novel calcium release-activated calcium (CRAC) channel ... Acute pancreatitis, sudden painful inflammation of ... can be very serious.  In severe cases it can ... hospital stays, time in the ICU and substantial ...
(Date:1/4/2017)... 2017  CES 2017 – Valencell , the ... announced the launch of two new versions of ... biometric sensor modules that incorporate the best of ... expertise. The two new designs include Benchmark BE2.0, ... and Benchmark BW2.0, a 2-LED version of its ...
(Date:12/20/2016)... , Dec. 20, 2016 The ... sharing, rental and leasing is stoking significant interest ... radio frequency technology, Bluetooth low energy (BLE), biometrics ... as the next wave of wireless technologies in ... access system to advanced access systems opens the ...
Breaking Biology News(10 mins):
(Date:1/17/2017)... ... 17, 2017 , ... Pono Ola , a mind-body wellness firm on ... the official launch of its much-anticipated Pono Board: a re-invented fitness and anti-fatigue balance ... for over a year, the patented Pono Board is the world’s only exercise balance ...
(Date:1/17/2017)... ... January 17, 2017 , ... Diagenode, a leading ... a collaboration with the Heidelberg University Hospital and the German Cancer Research Center ... the company’s successful launch of its CATS (Capture and Amplification by Tailing ...
(Date:1/16/2017)... ... January 16, 2017 , ... Appellate Court of ... on the appeal filed by India-based Dishman Pharmaceutical & Chemical Ltd. company (DPCL) ... and one of its Dishman Group’s 100% wholly owned New Jersey-based subsidiary Dishman ...
(Date:1/16/2017)... , Jan. 16, 2017  Eurofins Genomics today ... will allow more customers to receive their primers in ... or compromise in quality found with other providers. Express ... United States at no additional fee. ... routine genetic studies, including DNA sequencing, genotyping, site-directed mutagenesis, ...
Breaking Biology Technology:
Cached News: