HOME >> BIOLOGY >> NEWS
Iron can have negative side effects on people with kidney disease

More than 20 million Americans one in nine adults have chronic kidney disease, and most don't even know it.[1] Physicians are constantly searching for the most effective therapies to help people with end-stage renal disease (ESRD), which occurs when kidney disease has progressed and about 90% of kidney function has been lost. While iron therapy is a common treatment for such patients, new evidence suggests that iron is potentially toxic and its long-term consequences are unknown. Given that intravenous iron can damage normal kidneys, its potential toxicity might be even greater in kidneys affected by disease.

The journal Kidney International, published by Blackwell on behalf of the International Society of Nephrology, just released findings from an experimental study revealing that intravenous iron therapy administered to patients with kidney disease may have negative side effects. More clinical studies need to be performed to corroborate the findings.

Dr. Richard Allen Zager, a prominent researcher who has served as a NIH funded investigator on kidney disease for the past 25 years, noted "This study will likely stimulate aggressive clinical investigation of the issues raised by the findings of this experimental paper." The study provides support for the concept that parenteral iron formulations are potentially toxic. Rather than helping patients, iron therapy may exacerbate progressive renal damage. Yet iron therapy remains essential in the treatment of patients with chronic kidney disease.

This study points out that the level of toxicity depends on the nature of the iron formula given to patients. The four types of formulationsiron dextran (INFeD from Watson Pharmaceuticals), iron sucrose (Venofer from American Regent), iron gloconate (Ferrlecit from Watson Pharmaceutics) and Feoligosaccharide (FeOS, currently in clinical trials from Pharmacosmos) are statistically different in their toxicity in this study. In highlighting the difference
'"/>

Contact: Sharon Agsalda
medicalnews@bos.blackwellpublishing.net
781-388-8507
Blackwell Publishing Ltd.
30-Jul-2004


Page: 1 2

Related biology news :

1. Synthetic hormone used in contraceptives and HRT produces negative effects in monkey studies
2. Nonalcoholic beverages may impart cardiovascular benefits without the negative effects of alcohol
3. Even mild vitamin C deficiency may have negative effect on vascular function
4. Kaposis sarcoma-associated herpesvirus causes no negative health effects in hiv-negative individuals, find University of Pittsburgh researchers
5. Parents escape drinking evokes childrens negative response to alcohol smell
6. CU studies suggest exercise protects body against negative effects of stress from brain to cell
7. 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
8. Long-term effects of carbon monoxide poisoning are an autoimmune reaction
9. Marathoning mice could have Olympian effects on obesity
10. Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
11. Manipulating biotope space can enhance beneficial biodiversity effects

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... LAKE CITY, and MARTINSRIED, Germany (PRWEB) , ... ... ... in high-throughput antibody screening and characterization, announced today that they have opened a ... Carterra’s platform has fueled the need for the new office. , The Munich ...
(Date:8/14/2019)... JOLLA, Calif. (PRWEB) , ... August 14, 2019 , ... ... insight into their future children, announces inclusion in the 38th annual Inc. 500|5000 ... been eligible to apply. To qualify, companies must have been founded and generating revenue ...
(Date:8/9/2019)... ... August 09, 2019 , ... With a demand in healthcare to ... patients will visit urgent care centers (UCC) in the coming years, according to a ... The Market for Urgent Care Centers , is a detailed look at the current ...
Breaking Biology News(10 mins):
(Date:9/2/2019)... DENVILLE, N.J. and LIÉGE, Belgium (PRWEB) , ... ... ... provider of solutions for epigenetics research and in vitro diagnostics, has launched the ... to uncover the underlying biological meaning of epigenetic data and other data ...
(Date:8/29/2019)... ... August 29, 2019 , ... ... in the Sustainable Medicines in Africa program, which includes a master’s degree in ... Arusha, Tanzania September 2nd through 13th, 2019. Topics to be addressed include ...
(Date:8/25/2019)... VEGAS (PRWEB) , ... August 23, 2019 , ... ... with International No. 1 best-selling status for the scientific research book “Impact of ... in the cosmetic and perfume industry as Patchouli. , The book garnered ...
(Date:8/15/2019)... (PRWEB) , ... August 15, 2019 , ... ... Scientific Advisory Board. Mr. Lawrence is a member of the Institute of Food ... Safety and Health (IFSH) Advisory Board, Joint Institute for Food Safety and Applied ...
Breaking Biology Technology:
Cached News: