Israeli fertility experts call for international chromosome registry

Lausanne, Switzerland: If a woman undergoing artificial reproductive techniques suffers repeated failures of embryos to implant in her uterus it may be because she has a chromosomal abnormality, according to new findings by Israeli fertility experts.

A team from the Assaf Harofeh Medical Centre in Tel Aviv carried out genetic screening on 65 couples who had experienced repeated embryo implantation failure and found that a quarter of the women and the husbands of two of them had abnormal chromosomes.

The study, led by Professor Raphael Ron-El, head of the centre's IVF unit, was too small to establish a causal link between chromosome abnormalities and repeated implantation failure, so the research team is calling for an international registry to be established for chromosomal aberrations in infertility patients.

Team member Dr Arieh Raziel told the European Society of Human Reproduction and Embryology meeting in Lausanne today (Wednesday 4 July) that they had gathered 16 cases of chromosomal changes in three years. "Even if an additional 15 IVF units joined the study, the numbers would still be too small to draw conclusions. So we need an international registry set up that will record infertility patients' chromosomal aberrations and their impact on pregnancy."

He said that women undergoing ART have a seven-fold higher prevalence of autosomal (non-sex chromosome) translocations than the general population, with over one in a hundred patients affected. The highest rate was found in women with recurrent miscarriages.

"If the causes for implantation failure after IVF are similar to the causes for recurrent miscarriages, but in an earlier phase, then chromosomal abnormalities could also be more frequent in implantation failure," he told the conference. The objective of the study was to find the type and frequency of chromosomal changes in implantation failure and evaluate their impact on the outcome of the pre

Contact: Margaret Willson
European Society for Human Reproduction and Embryology

Page: 1 2

Related biology news :

1. Israeli scientists reveal the plan of a key cellular machine
2. Study by Israeli scientists provides insight on DNA code
3. Scientists identify a gene causing a fatal heart condition, common in an Israeli Bedouin tribe
4. Israeli scientists block the progression of Type I diabetes
5. Israeli scientists discover gene responsible for hereditary muscle disease prevalent among Jews of Persian descent
6. Israeli teams grows heart cells and insulin producing cells from human embryonic stem cells
7. Dr. Robert C. Gallo to Collaborate with Visiting Israeli Scientist on Promising HIV Vaccine Research at Marylands Institute of Human Virology
8. Researchers develop white wine with cholesterol-lowering benefits, discover Israeli wines healthier than French wines
9. Hopkins, Israeli Scientists Link Soybeans With Pain Relief
10. Sugar-coated sea urchin eggs could have sweet implications for human fertility
11. Research reveals role of gene in infertility

Post Your Comments:

(Date:11/11/2019)... Fla. (PRWEB) , ... November 11, 2019 , ... ... Sequencing (NGS) in microbial identification, played a key role in the award-winning study ... led by the Rothman Institute. The molecular diagnostic laboratory processed samples using Next ...
(Date:11/7/2019)... ... 2019 , ... R3 Stem Cell is now offering its comprehensive Online ... code to use during checkout is FIFTYOFF and applies to both the one month ... regenerative therapies with over 12,000 successful stem cell procedures performed nationwide. A couple years ...
(Date:11/6/2019)... , ... November 06, 2019 , ... ... version 2.0 today. The Genomic Search Engine now includes the ability to search ... further accelerate diagnosis of patients with genetic and rare diseases. , Patients, particularly ...
Breaking Biology News(10 mins):
(Date:11/2/2019)... ... 2019 , ... A clinical trial usually involves many different ... principal investigators, supply chain managers, manufacturers, IRT, CRAs and so on. Lack of ... data, potentially leading to patient risk. , By having a single source of ...
(Date:11/2/2019)... NEW YORK (PRWEB) , ... October 31, 2019 ... ... just been released by pharma artificial intelligence pioneer tellic. drug360 brings tellic’s ... data. This new tool allows researchers to quickly uncover relationships between genes, diseases, ...
(Date:10/30/2019)... ... 2019 , ... Western University of Health Sciences held Innovation ... in educating the next generation of health care providers. , The event, organized ... administrators and representatives of companies working with the University on a range of ...
(Date:10/29/2019)... ... 29, 2019 , ... Modality Solutions, a biopharmaceutical ... chain validation workshop at the Biomanufacturing World Summit (BMWS19) Conference, November 11-12, 2019, ... Biomanufacturing World Summit brings together pharmaceutical executives, cutting-edge technology providers, and ...
Breaking Biology Technology:
Cached News: