HOME >> BIOLOGY >> NEWS
Israeli scientists block the progression of Type I diabetes

Rehovot, Israel -- November 26, 2001--A team of researchers led by Prof. Irun Cohen of the Weizmann Institute of Science has developed a unique approach for halting the progression of Type I (juvenile or insulin-dependent) diabetes.

Cohen and Dr. Dana Elias (then a postdoctoral fellow at the Institute) discovered that injecting mice with a small peptide fragment known as p277 prevents the progression of Type I diabetes. Based on the results of his research, Peptor, a biopharmaceutical company from Rehovot, Israel, developed DiaPep277, an experimental drug designed to prevent or treat Type I diabetes.

A recent clinical study performed by researchers at Hadassah-Hebrew University Medical School and Peptor Ltd. proved that DiaPep277 is successful in arresting the progression of Type I diabetes in newly diagnosed patients. The research findings are published in the November 24, issue of The Lancet.

The study was of 35 patients newly diagnosed with Type I diabetes. Eighteen patients received injections of DiaPep277 at the beginning of the study, at one month, and at six months; 17 patients received three injections of an inert substance (placebo). Patients in the treatment group (those receiving DiaPep277) showed a halt or delay in the attack upon, or destruction of their pancreatic insulin-producing cells by the immune system. These results were evident in the level of the bodys own insulin production and in a decreased need for insulin injections. The researchers were able to trace the mechanism of this improvement to changes in the patients immune lymphocytes called T-cells. In contrast, patients receiving the placebo showed a significant decline in their natural insulin production and a persistent rise in the need for insulin injections. No significant side effects as a result of injecting DiaPep277 were found.

Diabetes is a chronic disease associated with elevated blood sugar levels, in which the body does not produce or properly us
'"/>

Contact: Jeffrey Sussman
jeffrey@acwis.org
212-895-7951
American Committee for the Weizmann Institute of Science
22-Nov-2001


Page: 1 2

Related biology news :

1. Israeli scientists reveal the plan of a key cellular machine
2. Study by Israeli scientists provides insight on DNA code
3. Scientists identify a gene causing a fatal heart condition, common in an Israeli Bedouin tribe
4. Israeli scientists discover gene responsible for hereditary muscle disease prevalent among Jews of Persian descent
5. Israeli teams grows heart cells and insulin producing cells from human embryonic stem cells
6. Israeli fertility experts call for international chromosome registry
7. Dr. Robert C. Gallo to Collaborate with Visiting Israeli Scientist on Promising HIV Vaccine Research at Marylands Institute of Human Virology
8. Researchers develop white wine with cholesterol-lowering benefits, discover Israeli wines healthier than French wines
9. Hopkins, Israeli Scientists Link Soybeans With Pain Relief
10. DNA lends scientists a hand, revealing new chemical reactions
11. Conference at UH opens doors for new scientists, engineers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2020)... , ... June 23, 2020 , ... ... is pleased to announce the next event in a series of TOPIQ webinars, ... The TOPIQ series of webinars was developed in response to social distancing measures ...
(Date:6/19/2020)... ... 16, 2020 , ... The director of stem cell biotechnology company Asymmetrex ... medicine and pharmaceutical industries have easier access to stem cell counting, they will soon ... this year, Independence Day weekend in the U.S., Asymmetrex is offering free tissue stem ...
(Date:6/19/2020)... ... June 18, 2020 , ... Join experts from Envigo Lauren ... a live webinar on Wednesday, July 8, 2020 at 11am EDT (4pm ... genetically engineer new models. However, while modifying the genome may be more straightforward, the ...
Breaking Biology News(10 mins):
(Date:6/28/2020)... Md. (PRWEB) , ... June 26, 2020 , ... ... trade association representing security solutions providers, today announced its strong opposition to the ... The bill would impose a blanket ban on most federal use of nearly ...
(Date:6/23/2020)... ... June 22, 2020 , ... Dracen Pharmaceuticals ... be presented June 22-24 during the American Association for Cancer Research Virtual meeting. ... profiles the potent, consistent single agent activity in KEAP1 mutant tumor models of ...
(Date:6/11/2020)... ... June 09, 2020 , ... ... of a Small Business Innovation Research (SBIR) program funded by the National Institute ... Toxin Detection in the Field”. The project’s goal was to engineer and develop ...
(Date:6/2/2020)... ... June 01, 2020 , ... As part ... positive change in the world, enterprise security solutions provider bitsIO donated time to ... working from home during self-quarantines and shelter-in-place orders, companies are increasingly concerned about ...
Breaking Biology Technology:
Cached News: