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JCI Table of Contents, April 1, 2003

ed the presence of PPT-A mRNA and neurokinin-like immunoreactivity in airway neurons and inflammatory cells. Interested in the interaction between these two cellular reservoirs of neurokinins in the lung, J. Julio Prez Fontn and colleagues examined their role in protection against both immune-complexmediated and mechanical lung injury in a murine model (pages 973980). The data revealed that the PPT-A gene must be functional in both sensory nerves and hematopoietic cells to propagate neurogenic inflammation and injury in the lung -- an unexpected synergy between sensory nerve fibers and PPT-A geneexpressing inflammatory cells.

CONTACT:
J. Julio Perez Fontan
Washington University School of Medicine
St. Louis Children's Hospital
Department of Pediatrics
One Children's Place
St. Louis, MO 63110
USA
Phone: 1-314-454-2527
Fax: 1-314-361-0733
E-mail: fontan@kids.wustl.edu

View the PDF of this article at:
https://www.the-jci.org/press/17458.pdf

Normal Levels of Anticoagulant Heparan Sulfate are not Essential for Normal Hemostasis.
CONTACT:
Nicholas Shworak
Dartmouth Medical School
Borwell 540, HB7504
Dartmouth Hitchcock Medical Center
One Medical Center Drive
Lebanon, NH 03756
USA
Phone: 1-603-650-6401
Fax: 1-603-653-0510
E-mail: nicholas.shworak@dartmouth.edu

View the PDF of this article at:
https://www.the-jci.org/press/15809.pdf

ACCOMPANYING COMMENTARY:
Heparan sulfate: antithrombotic or not?
CONTACT:
Jeffrey I. Weitz
Hamilton Civic Hospitals Research Centre
711 Concession Street
Hamilton, Ontario, L8
'"/>

Contact: Brooke Grindlinger
science_editor@the-jci.org
212-342-9006
Journal of Clinical Investigation
1-Apr-2003


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