TITLE: Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy
The University of Tokyo, Bunkyo, Tokyo, Japan.
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Immunology Link May Make You Lose Your Appetite
A decrease in food ingestion and anorexia are common symptoms during injury, illness, or inflammation. A key to the link between food intake and illness may be a recently identified molecule called ghrelin, which has previously been shown to play a part in maintaining metabolic energy balance. Now Dennis Taub and colleagues from the National Institute on Aging, have added to the ghrelin's role in the body, and show it also has activity in the immune system. They found that ghrelin receptors are expressed in cells in the immune system, and upon exposure to ghrelin, there was an inhibition of the production of molecules involved in the body's inflammatory response. The results here may furt
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Journal of Clinical Investigation