The data suggest that FGF-2 supplementation might provide a rational strategy to treat brain injury by simultaneously enhancing neurogenesis and reducing neurodegeneration.
In an accompanying Spotlight article on neurogenesis and brain injury, Daniel A. Peterson and colleagues from Chicago Medical School discuss the most recent developments in managing renewable cells for post-injury brain repair.
TITLE: FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice
Michael A. Moskowitz
Massachusetts General Hospital, Charlestown, Massachusetts, USA.
Phone: (617) 726-8442
Fax: (617) 726-2547
View the PDF of this article at: https://www.the-jci.org/press/16618.pdf
Neurogenesis and brain injury: managing a renewable resource for repair
Daniel A. Peterson
Department of Neuroscience, The Chicago Medical School, North Chicago, Illinois, USA.
Phone: (847) 578-3411
Fax: (847) 578-8545
View the PDF of this Spotlight article at: https://www.the-jci.org/press/20098.pdf
Enigmatic role for NF-kappaB in the hardening of arteries
A report in the October 15 issue of the Journal of Clinical Investigation resulting from a collaboration led by Menno P.J. de Winther and researchers at Vrije University, Maastricht University, Technical University of Munich, and Harvard Medical School, reveals tha
Contact: Brooke Grindlinger
Journal of Clinical Investigation