HOME >> BIOLOGY >> NEWS
JCI table of contents, July 15, 2003

Cell Biology in Sydney, Australia, have identified a novel function for BAFF: it acts as a specific survival factor for Ig-secreting cells derived from memory B cells. The study suggest that in human autoimmune diseases, elevated levels of serum BAFF may contribute to the disease process by not only breaking tolerance at the immature/transitional B cell stage of development, but by also enhancing plasmablast survival.

TITLE: BAFF selectively enhances the survival of plasmablasts generated from human memory B cells

AUTHOR CONTACT:
Stuart Tangye
Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Australia.
Phone: 61-2-9565-6127
Fax: 61-2-9565-6103
E-mail: s.tangye@centenary.usyd.edu.au

View the PDF of this article at: https://www.the-jci.org/press/18025.pdf


Secret to controlling thyroid hormone production

Originating in the thyroid, the prohormone thyroxine is converted to triiodothyronine, which is essential in brain development, growth, and metabolism. A study from researchers at Brigham and Women's Hospital in Boston, reveals a novel mechanism for controlling triiodothyronine production that demonstrates the first example of enzyme activity being restored by deubiquitination.

TITLE: Deubiquitination of type 2 iodothyronine deiodinase by von HippelLindau proteininteracting deubiquitinating enzymes regulates thyroid hormone activation

AUTHOR CONTACT:
Antonio C. Bianco
Harvard University, Boston, Massachusetts, USA.
Phone: 617-525-5153
Fax: 617-731-4718
E-mail: abianco@partners.org

View the PDF of this article at: https://www.the-jci.org/press/18348.pdf

ACCOMPANYING COMMENTARY:
Ubiquitinated dei
'"/>

Contact: Brooke Grindlinger
science_editor@the-jci.org
212-342-9006
Journal of Clinical Investigation
15-Jul-2003


Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14

Related biology news :

1. Chemical engineering grad students will take notable national awards
2. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
3. JCI table of contents September 15, 2004
4. JCI table of contents: 1 September, 2004
5. Anti-cancer compound in vegetables found to block late-stage breast-cancer cell growth
6. JCI table of contents, 16 August, 2004
7. JCI table of contents, 2 August, 2004
8. When male fish hum, females swim in, thanks to hormones, adaptable hearing
9. JCI table of contents, 1 July 2004
10. Search and destroy protein turns tables on HIV
11. JCI table of contents, 15 June 2004

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: JCI table contents July

(Date:10/16/2014)... Cancer constantly wages war on the human body. ... a stalemate. In pancreatic cancer, this stalemate—known as ... becoming aggressively malignant, a phenomena that is poorly ... in the laboratory of Salvatore Torquato, a Professor ... the conditions surrounding tumor dormancy and the switch ...
(Date:10/16/2014)... are anything but sustainable: environmental damage to soil ... increasingly evident. Despite their disadvantages, however, monocultures remain ... the sole possibility of achieving higher yields in ... an ecology professor at the University of Zurich, ... forestry. After all, a new study carried out ...
(Date:10/15/2014)... , Oct. 15, 2014 Sandata ... for home and community-based care, today announced it ... implementing Sandata,s Santrax® Electronic Visit Verification™ Solution (EVV™) ... is a home health company founded in 1996 ... . The study details ...
Breaking Biology News(10 mins):Modeling tumor dormancy 2Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3Sandata Announces Case Study with Quality Care Services, Inc. 2
(Date:10/20/2014)... ON , Oct. 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: ... $1.7 million which brings Q3 orders to $5.8 million and provides ... control projects in North America and one ... continue to bid new projects at record levels," said Peter ... were higher at the end of Q3 than they have been ...
(Date:10/20/2014)... , Oct. 20, 2014 PureTech , ... tackling big healthcare problems, announced today the closing ... with participation from Invesco Perpetual, a $120 Billion ... to drive PureTech,s existing pipeline forward and to ... has the scientific creativity to really go for ...
(Date:10/20/2014)... Tigard, OR (PRWEB) October 20, 2014 ... to participate in an investigational study of donor stem ... nationally in stem cell therapy and has performed clinical ... of this study is to determine if a single ... arthritically affected joints can help reduce pain and inflammation ...
(Date:10/19/2014)... 19, 2014 NextCODE Health, which enables clinicians and ... real time, today announced the launch of its new genomic ... at the American Society of Human Genetics (ASHG) annual meeting ... sign up and apply for free beta access, visit ... benefits can be viewed here . The ...
Breaking Biology Technology:PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6Cascade Veterinary Referral Center Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3
Cached News: