Jefferson Researchers First To Create Genetically Engineered Mouse To Study Photoaging

Embargoed until Tuesday, February 17, 1998 at 12:30 p.m. EST. Dr. Jouni Uitto will present study results at the 1998 American Association for the Advancement of Science (AAAS) annual meeting at the Pennsylvania Convention Center, Philadelphia, Pa.

Jefferson Researchers First to Create Genetically Engineered Mouse to Study Photoaging Transgenic mouse leading to better understanding of how ultraviolet light exposure contributes to skin aging and skin cancer and the development of new, better sunscreens that may prevent both.

Researchers from Jefferson Medical College of Thomas Jefferson University, Philadelphia, have developed the first transgenic, or genetically altered, mouse used to study the causes and effects of photoaging on human skin. The mouse line, developed by microinjecting fertilized mouse eggs with human elastin promoter DNA, the material which produces skin fibers that promote elasticity, has enabled Jefferson researchers to learn more about how the ultraviolet light rays UVA and UVB cause skin aging and wrinkling.

Study results have also led to new ideas for how sunscreen formulations and other compounds may be designed to block the skin from the dangers of UVB, which many already do, and UVA, which causes skin aging and may play a role in skin cancer but is not blocked as well by traditional sunscreens. These findings will be presented by Jouni Uitto, M.D., Ph.D., professor and chairman of the department of dermatology and cutaneous biology at Jefferson Medical College of Thomas Jefferson University, at the 1998 American Association for the Advancement of Science (AAAS) annual meeting in Philadelphia, on Tuesday, February 17.

Dr. Uitto's presentation, "Molecular Assays for Solar Effects in Skin," will serve as part of a larger seminar, "Sunscreen and Skin Cancer: What's Happening," proposed and organized by Francis Gasparro, Ph.D., research

Contact: Maria Cerceo or Phyllis Fisher
Thomas Jefferson University

Page: 1 2 3 4

Related biology news :

1. Jefferson Lab detector technology aids development of cystic fibrosis therapy
2. Jefferson scientists find gene expression pattern may predict behavior of leukemia
3. Jefferson researchers develop microchip to track genetic signature of cancer and normal tissue
4. Jefferson scientists use gene therapy to restore function of damaged heart cells in lab
5. Jefferson researchers uncover biochemical clues to how cells migrate in embryos
6. Jefferson and Brigham and Womens researchers find blue light important for setting biological clock
7. Jefferson Lab experiment generates THz radiation 20,000 times brighter than anyone else
8. Jefferson scientists show neural stem cells can become dopamine-making brain cells in laboratory
9. Jefferson scientists show how collagen gene mutation leads to osteoarthritis
10. Jefferson scientists use gene repair technique to change albino mice hairs to black
11. Jefferson scientists show drug is effective against a Hepatitis C Virus model in the laboratory

Post Your Comments:

(Date:10/29/2015)... Minn. , Oct. 29, 2015   MedNet ... supports the entire spectrum of clinical research, is pleased ... Minnesota High Tech Association (MHTA) as one of only ... in the "Software – Small and Growing" category. The Tekne ... individuals who have shown superior technology innovation and leadership. ...
(Date:10/29/2015)... 29, 2015  Connected health pioneer, Joseph C. ... of technology-enabled health and wellness, and the business opportunities ... The Internet of Healthy Things . Long ... even existed, Dr. Kvedar, vice president, Connected Health, Partners ... delivery, moving care from the hospital or doctor,s office ...
(Date:10/27/2015)... 27, 2015 Munich, Germany ... Mapping technology (ASGM) automatically maps data from mobile eye ... , so that they can be quantitatively analyzed ... Munich, Germany , October 28-29, 2015. SMI,s ... from mobile eye tracking videos created with SMI,s ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... ... November 24, 2015 , ... ... But unless it is bound to proteins, copper is also toxic to cells. ... at Worcester Polytechnic Institute (WPI) will conduct a systematic study of copper in ...
(Date:11/24/2015)... , November 24, 2015 ... market research report "Oligonucleotide Synthesis Market by Product & ... Gene Synthesis, Diagnostic, DNA, RNAi), End-User (Research, Pharmaceutical & ... by MarketsandMarkets, the market is expected to reach USD ... 2015, at a CAGR of 10.1% during the forecast ...
(Date:11/24/2015)... November 24, 2015 --> ... research report released by Transparency Market Research, the global ... a CAGR of 17.5% during the period between 2014 ... - Global Industry Analysis, Size, Volume, Share, Growth, Trends ... prenatal testing market to reach a valuation of US$2.38 ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... are paramount. Insertion points for in-line sensors can represent a weak spot where ... InTrac 781/784 series of retractable sensor housings , which are designed to tolerate ...
Breaking Biology Technology:
Cached News: