HOME >> BIOLOGY >> NEWS
Jefferson Researchers First To Create Genetically Engineered Mouse To Study Photoaging

Embargoed until Tuesday, February 17, 1998 at 12:30 p.m. EST. Dr. Jouni Uitto will present study results at the 1998 American Association for the Advancement of Science (AAAS) annual meeting at the Pennsylvania Convention Center, Philadelphia, Pa.

Jefferson Researchers First to Create Genetically Engineered Mouse to Study Photoaging Transgenic mouse leading to better understanding of how ultraviolet light exposure contributes to skin aging and skin cancer and the development of new, better sunscreens that may prevent both.

Researchers from Jefferson Medical College of Thomas Jefferson University, Philadelphia, have developed the first transgenic, or genetically altered, mouse used to study the causes and effects of photoaging on human skin. The mouse line, developed by microinjecting fertilized mouse eggs with human elastin promoter DNA, the material which produces skin fibers that promote elasticity, has enabled Jefferson researchers to learn more about how the ultraviolet light rays UVA and UVB cause skin aging and wrinkling.

Study results have also led to new ideas for how sunscreen formulations and other compounds may be designed to block the skin from the dangers of UVB, which many already do, and UVA, which causes skin aging and may play a role in skin cancer but is not blocked as well by traditional sunscreens. These findings will be presented by Jouni Uitto, M.D., Ph.D., professor and chairman of the department of dermatology and cutaneous biology at Jefferson Medical College of Thomas Jefferson University, at the 1998 American Association for the Advancement of Science (AAAS) annual meeting in Philadelphia, on Tuesday, February 17.

Dr. Uitto's presentation, "Molecular Assays for Solar Effects in Skin," will serve as part of a larger seminar, "Sunscreen and Skin Cancer: What's Happening," proposed and organized by Francis Gasparro, Ph.D., research
'"/>

Contact: Maria Cerceo or Phyllis Fisher
Maria.Cerceo@mail.tju.edu
215-955-6300
Thomas Jefferson University
17-Feb-1998


Page: 1 2 3 4

Related biology news :

1. Jefferson Lab detector technology aids development of cystic fibrosis therapy
2. Jefferson scientists find gene expression pattern may predict behavior of leukemia
3. Jefferson researchers develop microchip to track genetic signature of cancer and normal tissue
4. Jefferson scientists use gene therapy to restore function of damaged heart cells in lab
5. Jefferson researchers uncover biochemical clues to how cells migrate in embryos
6. Jefferson and Brigham and Womens researchers find blue light important for setting biological clock
7. Jefferson Lab experiment generates THz radiation 20,000 times brighter than anyone else
8. Jefferson scientists show neural stem cells can become dopamine-making brain cells in laboratory
9. Jefferson scientists show how collagen gene mutation leads to osteoarthritis
10. Jefferson scientists use gene repair technique to change albino mice hairs to black
11. Jefferson scientists show drug is effective against a Hepatitis C Virus model in the laboratory

Post Your Comments:
(Date:3/16/2015)... March 16, 2015 Between ... will present groundbreaking innovations in biometric identification at ... .      (Photo: http://photos.prnewswire.com/prnh/20150316/735333 ... innovation is well at the forefront: the company,s ... made in Germany . BiometricGate ...
(Date:3/12/2015)... The mascots of the Atlantic Coast Conference ... Wake Forest Baptist Medical Center. They stopped by as ... Men,s Basketball Tournament. Young patients enjoyed bonding with their ... autographs. Brenner Children,s Hospital is the pediatric ... children,s hospital in northwest North Carolina ...
(Date:3/12/2015)... , March 12, 2015 WHEN:Tuesday, March 17, ... here: http://bit.ly/1G7Os0L . SPEAKERS: , Frost & ... - http://photos.prnewswire.com/prnh/20150311/181111 Biometric companies ... compete in several different markets and industries. This ... witnessing an uptrend. Join Frost ...
Breaking Biology News(10 mins):DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3
(Date:4/1/2015)... 2015 Immunocore Limited ("the ... drugs to treat cancer, viral infections and autoimmune ... of Christina Coughlin as Chief Medical ... medical and regulatory leadership to the pre-clinical and ... Coughlin has extensive experience in oncology drug development, ...
(Date:3/31/2015)... , March 31, 2015  Biotest Pharmaceuticals Corporation ... pleased to announce the addition of its newest plasma ... 205 Conway, Arkansas . The over ... for business on March 26 th 2015 and ... to eighteen. "This facility represents another ...
(Date:3/31/2015)... 31, 2015 Eastern Kentucky University ... online bachelor’s of criminal justice degree programs by ... to inspiring ideas and high quality educational opportunities,” ... the University. We are confident that students will ... This is the site’s first “Students before Profits” ...
(Date:3/31/2015)... PA (PRWEB) March 31, 2015 Pittcon ... and Applied Spectroscopy, ended on March 12, in New ... at $21 million as estimated by the New Orleans ... more than 14,200 conferees and exhibitor personnel. Those ... of the conferee number. For the third year, the ...
Breaking Biology Technology:Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 2Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 3Immunocore Appoints Dr. Christina Coughlin as Chief Medical Officer 4Biotest Pharmaceuticals Corporation Announces the Opening of its Newest Plasma Collection Facility in Conway, Arkansas 2EKU Ranked in Top 50 Among Online Criminal Justice Degrees 2Pittcon 2015 Hits the Big Easy in a Big Way 2Pittcon 2015 Hits the Big Easy in a Big Way 3Pittcon 2015 Hits the Big Easy in a Big Way 4
Cached News: