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Jefferson scientists show drug is effective against a Hepatitis C Virus model in the laboratory

ow HCV, the researchers were able to block the creation of a virus "envelope," locking the virus within the infected cell. The virus, then, is rendered "dead," or non-infectious.

Acccording to Dr. Block, worldwide, HCV chronically infects some 100 million people, with as many as four million chronic carriers in the United States. Those at risk for contracting HCV include intravenous drug abusers and anyone who had transfusions prior to 1990, when blood supply screening for HCV began. Together, HBV and HCV chronically infect more than 400 million people in the world. Approximately one million people die each year from HBV- and HCV-related liver diseases, such as hepatitis, cirrhosis and cancer.

Scientists from several other institutions participated in the study, such as Nicole Zitzmann, Ph.D., Raymond Dwek, D. Phil., FRSC, Oxford University, and Nobel laureate Baruch Blumberg, M.D., Ph.D., Fox Chase Cancer Center.


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Contact: Steve Benowitz
steven.benowitz@mail.tju.edu
215-955-5291
Thomas Jefferson University
11-Oct-1999


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