HOME >> BIOLOGY >> NEWS
Joslin Diabetes Center launches research section on developmental and stem cell biology

tary directions of stem cell research.

Learning Lessons from a Lowly Worm

T. Keith Blackwell, M.D., Ph.D., previously an investigator at the Center for Blood Research in Boston, will lead the Section on Developmental and Stem Cell Biology.

Dr. Blackwell's laboratory uses a simple model organism the microscopic nematode (worm) Caenorhabditis elegans to study the regulation of genes important for the development of germ cells, which form the sperm and egg, and the early embryo. Germ cells represent an important stem cell model because they can give rise to an entire organism. According to Dr. Blackwell, C. elegans is an excellent model organism because its genes can be readily manipulated. By studying how key control genes are regulated, Joslin hopes to discover exactly how embryonic cells differentiate into various types of cells, which may lead to insights into how to reprogram human stem cells to develop into different types of cell including insulin-producing cells. In addition, Dr. Blackwell's work on germ cells in C. elegans is already uncovering basic principles of germ cell self-renewal and function that appear to be active in human embryonic stem cells.

Another major interest of the Blackwell lab is a gene-control circuit that in the early embryo initiates development of the digestive system, which includes the pancreas. This control mechanism later orchestrates one of the body's most important defenses against oxidative stress. Oxidative stress, or an excess of free radicals within the cell, is the major underlying cause of diabetic vascular disease and an important denominator of the health of insulin-producing cells. By understanding how these natural oxidative stress defenses are mobilized, Dr. Blackwell hopes in the future to identify new possibilities for antioxidant therapies that will combat or prevent diabetic complications.

Stem Cells Focus of Studies

Amy Wagers, Ph.D., recently
'"/>

Contact: Marjorie Dwyer
marjorie.dwyer@joslin.harvard.edu
617-732-2415
Joslin Diabetes Center
11-Aug-2004


Page: 1 2 3 4 5 6

Related biology news :

1. Joslin Diabetes Center honors brothers living 70-plus years with type 1 diabetes
2. Joslin researchers clarify mechanisms for beta-cell formation
3. Joslin President awarded medal from international diabetes organization
4. Joslin Diabetes Center adds first affiliate in California at Irvine Medical Center
5. New imaging technology at Joslin shown to detect early signs of type 1 diabetes
6. Joslin Diabetes Center releases new low impact exercise video
7. Joslin researchers identify key molecule in Type 1 diabetes progression
8. As obesity skyrockets, Joslin Diabetes Center urges action to stem the tide of type 2 diabetes
9. Diabetes drug may be new tool in treating breast cancer
10. Diabetes in the elderly linked to fewer cellular power plants
11. Diabetes therapies and liquid memory may develop from micro fluid research, Science researchers say

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... ... 2019 , ... Representatives with MyBioGate announced that China Focus@Biotech Week will be ... help innovative projects connect with Chinese pharma and investors in healthcare innovation,” said Miao ... explain that as a part of Biotech Week Boston – the annual biotech festival ...
(Date:8/14/2019)... ... August 13, 2019 , ... Dr. Julie Reck of Veterinary Medical Center of Fort ... Her first stem cell patient, her own geriatric Australian Shepherd, Simon, was treated in ... Simon wanted to play but his body was weak, and he struggled to play fetch ...
(Date:8/6/2019)... ... 06, 2019 , ... VetStem Biopharma has long ... manufacturing experience. In November it spun out a human regenerative medicine subsidiary, ... one of the first cGMP cell manufacturing facilities in California , VetStem ...
Breaking Biology News(10 mins):
(Date:9/11/2019)... Pa. (PRWEB) , ... September 09, 2019 , ... ... for life sciences companies and government agencies, announced that its president and CEO ... group of successful business leaders. , The Forbes Council accepted Gallivan based on ...
(Date:9/9/2019)... ... September 09, 2019 , ... Visikol CEO Dr. Michael Johnson recently gave a ... best to characterize 3D cell culture models. The inherent problem of characterizing 3D cell ... opaque to image through and therefore traditional wide-field or even confocal microscopy only tells ...
(Date:9/2/2019)... ... September 02, 2019 , ... Diagenode, ... diagnostics, has launched the industry’s first epigenetics data mining services that uses unique ... data and other data types. , Next generation sequencing in combination with ...
(Date:8/27/2019)... (PRWEB) , ... August 27, 2019 , ... Dr. Kim ... She recently opened North Peninsula Veterinary Surgical Group , a new surgical practice ... there are plans to expand and add more veterinary specialists as the practice grows. ...
Breaking Biology Technology:
Cached News: