HOME >> BIOLOGY >> NEWS
Landmark study offers new information about breast cancer genes

Bronxville, NY, October 22, 2003 A landmark study of Ashkenazi Jewish women with inherited mutations in the genes BRCA1 and BRCA2, called The New York Breast Cancer Study, will be published by Science Magazine on October 24, and reveals some surprising findings that will contribute significantly to the scientific knowledge in the field of breast cancer management. The study was the first to incorporate pre- and post-test genetic counseling, offered through the Sarah Lawrence College graduate program in Human Genetics, for enrolled subjects.

The study, which was based on one of the largest population samples ever collected in this area of research, provides the truest estimation to date of the lifetime risks of developing breast and ovarian cancer caused by mutations in the genes BRCA1 and BRCA2. Important scientific findings include:

  • New statistics about incidences of ovarian cancer among women with the gene mutation: Women who carry the BRCA1 gene have a 54% lifetime risk of developing ovarian cancer.
  • Groundbreaking information about the negative impact of obesity and lack of exercise among teenagers on breast cancer development as adult women: Exercise and appropriate weight during adolescence delayed the onset of breast cancer in women who carry the mutation.
  • Findings that relate the date of birth of the subjects to the risk of breast cancer: Women in this study who carried the breast cancer gene born before 1940 developed breast cancer later in life than those born after 1940.

Conducted by Dr. Mary-Claire King of the Departments of Medicine and Genome Sciences, University of Washington, Seattle and Joan H. Marks, MS and Jessica B. Mandell, MS, CGC, of the Graduate Program in Human Genetics at Sarah Lawrence College in Bronxville, NY, the study engaged over 1000 women of Ashkenazi Jewish background in the New York Metropolitan area.

More than 100 students in the Sarah Lawrence program served as res
'"/>

Contact: Judith Schwartzstein
judiths@sarahlawrence.edu
914-395-2219
Sarah Lawrence College
23-Oct-2003


Page: 1 2 3

Related biology news :

1. Landmark gene agreement announced by Samoan government and UC Berkeley for anti-AIDS drug Prostratin
2. Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
3. Landmark, pivotal Phase IIb/III trial of biotoxin for cancer pain begins
4. Landmark conference for United Nations on human cloning and stem cell research
5. Landmark completion of comprehensive index of human proteins to be presented at New York Academy of Sciences
6. Radical discovery dedicated a National Historic Chemical Landmark
7. Landmark obesity study
8. Landmark progress in understanding ribosome structure-- research done at Brookhaven Labs light source
9. Student science contest participation influences study, career choices, alumni say
10. New study shows hope for treating inhalant abuse
11. International study findings link acne-like rash to effectiveness of new targeted cancer treatment

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... ... July 01, 2020 , ... Catalent, a global ... of Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, located in the Shiga prefecture of ... located in Kakegawa, the new 60,000-square-foot facility will provide customers with flexible clinical ...
(Date:6/28/2020)... (PRWEB) , ... June 25, ... ... of enterprise software solutions for biopharmaceutical R&D, today announced that it has ... developing innovative, full-length multispecific antibodies (Multiclonics®), to support their translational and clinical ...
(Date:6/25/2020)... (PRWEB) , ... June 24, 2020 , ... ... cloud-based enterprise software and software-driven clinical data services that accelerate drug development, is ... low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... FARMS, Mich. (PRWEB) , ... August 12, 2020 ... ... Consulting Group, Inc. (EMMA International), a global leader in FDA compliance consulting ... of the nation’s fastest-growing private companies. The list represents a unique look at ...
(Date:7/31/2020)... Texas (PRWEB) , ... July 29, 2020 , ... ... solutions today announced the launch of its new tagline, “BUILDING FOR LIFE.” The ... biopharmaceutical industry and around the globe, requiring fast track capacity to provide patients ...
(Date:7/31/2020)... ... 29, 2020 , ... The SDX® Respiratory Gating System ... has reached its 20th anniversary of worldwide use. Introduced in the US over ... including University of Pennsylvania, University of Michigan, University of Maryland, University of California ...
(Date:7/18/2020)... ... July 16, 2020 , ... Medial EarlySign , ... and prevention of high-burden diseases, and Centric Consulting, a business and technology consulting ... utilize existing data in order to identify and prioritize patients for care. , ...
Breaking Biology Technology:
Cached News: