HOME >> BIOLOGY >> NEWS
Laser micro-scalpel yields biological insights into tissue dynamics

DURHAM, N.C. -- Using a laser beam scalpel so fine it could inscribe words on the surface of a fly egg, researchers have snipped their way to a new understanding of a key process in a fruit flys embryonic development. The process, called dorsal closure, is the complex mechanism by which the embryonic skin of the fruit fly Drosophila knits itself together to protect its innards from the outside world.

Understanding this seemingly arcane process is important because dorsal closure uses molecular and cellular mechanisms very similar to those involved in wound-healing as well as those that can go awry in humans to produce the spinal malformation spina bifida.

The researchers achievements were reported in an online article in the February 6, 2003, Sciencexpress -- and will appear in the April 4, 2003, print version of Science -- by an interdisciplinary Duke research team that includes biologists, physicists and a mathematician. It was this broad collaboration, said the scientists, that enabled them to refine the laser scalpel, to perform the microsurgery to dissect the fly tissue and to model the forces involved in key developmental machinery.

Dorsal closure is a good system for studying these processes because its tractable, said lead author Shane Hutson. We only have to deal with a few different kinds of cells that are arranged in a planar fashion.

According to Hutson -- a postdoctoral fellow in Dukes Free Electron Laser Laboratory (FELL) -- dorsal closure involves the interplay of forces among three kinds of tissues in the fly embryo, which is smaller than a grain of rice. The amnioserosa cells form an inner sheet of tissue involved in knitting the closure; the lateral epidermis is the tissue layer that ultimately forms the flys outer covering; and in between these two tissues is a group of leading edge cells that form a purse-string structure that somehow tightens to contribute to closure.

As closure proceeds, the cells of
'"/>

Contact: Dennis Meredith
dennis.meredith@duke.edu
919-681-8054
Duke University
27-Mar-2003


Page: 1 2 3 4

Related biology news :

1. Laser technique used to build micro-polymeric structure on a human hair, without harming it
2. Laser technology to map industrial plant gases available through Alberta Research Council
3. Lasers create new possibilities for biological technology
4. Laser-pulse technique could aid drug design
5. Researchers at Vanderbilts Free-Electron Laser Center are developing new forms of laser surgery, improved X-ray technology, and better methods for protein identification
6. Laser technique examines movement in nucleus of living cell
7. Laser treatment reduces scarring after heart attack
8. Laser surgery halts chest pain over the long-term; scientists also looking into non-surgical TMR
9. Lasers to the aid of embryos
10. Laser light from Free-Electron Laser used for first time in human surgery
11. Laser Microscope At Cornell Images Serotonin In Live Cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/18/2018)... POWAY, Calif. (PRWEB) , ... December 18, 2018 , ... ... Dressage. He has been competing for many years however in 2006, he had ... a trot. It was determined that he suffered from cartilage degeneration in his ...
(Date:12/13/2018)... ... December 13, 2018 , ... Study Protocol Summary of QC Procedure , 1 ... first assessment performed at the site., 3 - Three photos captured with Apple iPad ... in BOX., 5 - Photos moved to eAdjudication® and submitted to Reviewers., 6 - ...
(Date:12/13/2018)... , ... December 12, 2018 , ... ... advancement of regenerative cellular therapy, has announced the launch of Maxx-Cell, the world's ... a gold standard approach of aspirating a patients autologous bone marrow cells. Maxx™-Cell ...
Breaking Biology News(10 mins):
(Date:1/11/2019)... ... January 11, 2019 , ... Drawing on over 22 ... January 22, 2019 at 2:30pm EST will explore some of the key lessons that ... using one vendor vs. using multiple vendors, and find out how to ensure that ...
(Date:1/8/2019)... , ... January 08, 2019 , ... The American ... grant recipients were named by a selection committee made up of industry leaders identified ... The Career Development grants are mentored awards created to support ASGCT members designing transformative ...
(Date:1/4/2019)... ... January 03, 2019 , ... Calidi Biotherapeutics, ... cancer, today announced the founding of a scientific and medical advisory board (SMAB). ... key leaders in the Immuno-Oncology field. The founding members of Calidi Biotherapeutics SMAB ...
(Date:12/18/2018)... ... December 18, 2018 , ... USDM Life ... the life sciences industry, unveiled a completely redesigned website at http://www.usdm.com . ... browsing experience for their valued clients and business partners. , The website ...
Breaking Biology Technology:
Cached News: