HOME >> BIOLOGY >> NEWS
Lasker Award honors Rockefeller University biochemist for pioneering studies of gene activation

fat cells -- a finding that may one day contribute to new treatments for diabetes, heart disease, cancer and other conditions in which the fat-making process breaks down.

More recently, in the journal Cell, Roeder's lab has reported that a coactivator called OCA-S -- a relative of coactivator OCA-B -- is activated during a specific phase of the cell cycle, when the DNA is duplicated and the number of chromosomes doubles. The activation of OCA-S in turn leads to the production of new histones. Histones are spool-like proteins that DNA wraps around to condense and compact itself in the nucleus of all body cells.

An unexpected but extremely exciting finding was that a key component of this complex proved identical to a cellular (cytoplasmic) enzyme long implicated in metabolism and energy production, thus linking the regulation of cell growth and proliferation (through the control of histone biosynthesis) to the metabolic state of the cell. These findings add to a growing body of research from the Roeder lab that is beginning to define more specific physiological roles for the poorly understood coactivators.

Four decades of honors

Roeder was born in Boonville, Indiana, in 1942. He received a B.A. degree summa cum laude in chemistry from Wabash College in 1964, an M.S. in chemistry from the University of Illinois in 1965, and a Ph.D. in biochemistry from the University of Washington, Seattle, in 1969. He completed postdoctoral work at the Carnegie Institution of Washington, in Baltimore, from 1969 to 1971.

He was named assistant professor of biological chemistry at Washington University in St. Louis in 1971, associate professor in 1975, and professor in 1976. In 1978, he was appointed professor of genetics, and in the following year, was named James S. McDonnell Professor of Biochemical Genetics. In 1982, he accepted a professorship at Rockefeller University and organized a new Laboratory of Molecular Biology and Biochem
'"/>

Contact: Joseph Bonner
bonnerj@mail.rockefeller.edu
212-327-8998
Rockefeller University
13-Sep-2003


Page: 1 2 3 4 5 6 7 8

Related biology news :

1. Clay M. Armstrong, MD, wins 1999 Albert Lasker Basic Medical Research Award
2. Gladstone investigator Mike McCune wins prestigious NIH Directors Pioneer Award
3. UT Southwestern biochemist honored with NIH Directors Pioneer Award
4. Award winning researchers reveal potential new role for Glivec
5. UMaine anthropologist wins Solon T. Kimball Award
6. Secretary of Energy announces seven E.O. Lawrence Award Winners
7. Martin Saunders to receive the James Flack Norris Award
8. Berkeley Lab soil scientist Margaret Torn receives Presidential Early Career Award
9. NJIT professor receives Presidential Award for breakthrough research with adult stem cells
10. Second call for proposals for the European Young Investigator Award
11. Virginia Tech professor honored with DeLaval Award

Post Your Comments:
(Date:4/2/2015)... , April 2, 2015 ... tests DERMALOG by far outperforms the strongest competitors, ... maintaining high accuracy, the system is capable of ... the speed proves up to be ten times ... than its runner-up performance.      (Photo: ...
(Date:4/2/2015)... 2, 2015 Fingerprint Cards (FPC) ... FPC1025 from the distributor World Peace Industrial Group (WPI), ... 2015 although the major part of the shipments will ... used by smartphone manufacturers in China ... in the communicated revenue guidance of + 1 000 MSEK ...
(Date:3/31/2015)... 31, 2015  Elephant Talk Communications Corp. (NYSE MKT: ... of Software Defined Network Architecture (ET Software DNA® 2.0) ... of approximately $20.4 million for the year ended December ... for the year ended December 31, 2013. ... had completed its multi-year transition away from its legacy ...
Breaking Biology News(10 mins):DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
(Date:4/23/2015)... -- Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced today ... results before the Nasdaq market opens on Thursday, April ... and webcast to discuss its financial results and provide ... 8:00 a.m. Eastern Time (5:00 a.m. Pacific Time). ... dialing 866-952-1906 (US) or 785-424-1825 (International) using the conference ...
(Date:4/23/2015)... LONDON , April 23, 2015 ... Medical Equipment   Report Details   ... reach a value of $101.3 billion in 2015 and will ... Strong growth in the healthcare sectors around the world and ... the key growth factors in the global healthcare packaging ...
(Date:4/23/2015)... 23, 2015 /PRNewswire/ - Crystal Research Associates, LLC announced ... ® (EIO) on Aeterna Zentaris Inc. (NASDAQ: ... on Crystal Research Associates, website at www.crystalra.com ... at www.aezsinc.com . Aeterna Zentaris ("Aeterna" ... company in oncology, endocrinology, and women,s health. With a ...
(Date:4/22/2015)... MN , April 22, 2015 /PRNewswire/ - BioAmber Inc. (NYSE and ... for the first quarter 2015 on Thursday, May 7, ... has scheduled a webcast and conference call for 4.30 ... Live audio of the conference call ... available to investors, members of the news media and ...
Breaking Biology Technology:Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2Healthcare Packaging Market Forecast 2015-2025 2Healthcare Packaging Market Forecast 2015-2025 3Healthcare Packaging Market Forecast 2015-2025 4Healthcare Packaging Market Forecast 2015-2025 5Healthcare Packaging Market Forecast 2015-2025 6Healthcare Packaging Market Forecast 2015-2025 7Healthcare Packaging Market Forecast 2015-2025 8Healthcare Packaging Market Forecast 2015-2025 9Healthcare Packaging Market Forecast 2015-2025 10Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 2Crystal Research Associates, LLC Issues Executive Informational Overview (EIO) on Aeterna Zentaris Inc. 3BioAmber Announces Webcast of Fiscal First Quarter 2015 Financial Results 2
Cached News: