HOME >> BIOLOGY >> NEWS
Lasker Award honors Rockefeller University biochemist for pioneering studies of gene activation

fat cells -- a finding that may one day contribute to new treatments for diabetes, heart disease, cancer and other conditions in which the fat-making process breaks down.

More recently, in the journal Cell, Roeder's lab has reported that a coactivator called OCA-S -- a relative of coactivator OCA-B -- is activated during a specific phase of the cell cycle, when the DNA is duplicated and the number of chromosomes doubles. The activation of OCA-S in turn leads to the production of new histones. Histones are spool-like proteins that DNA wraps around to condense and compact itself in the nucleus of all body cells.

An unexpected but extremely exciting finding was that a key component of this complex proved identical to a cellular (cytoplasmic) enzyme long implicated in metabolism and energy production, thus linking the regulation of cell growth and proliferation (through the control of histone biosynthesis) to the metabolic state of the cell. These findings add to a growing body of research from the Roeder lab that is beginning to define more specific physiological roles for the poorly understood coactivators.

Four decades of honors

Roeder was born in Boonville, Indiana, in 1942. He received a B.A. degree summa cum laude in chemistry from Wabash College in 1964, an M.S. in chemistry from the University of Illinois in 1965, and a Ph.D. in biochemistry from the University of Washington, Seattle, in 1969. He completed postdoctoral work at the Carnegie Institution of Washington, in Baltimore, from 1969 to 1971.

He was named assistant professor of biological chemistry at Washington University in St. Louis in 1971, associate professor in 1975, and professor in 1976. In 1978, he was appointed professor of genetics, and in the following year, was named James S. McDonnell Professor of Biochemical Genetics. In 1982, he accepted a professorship at Rockefeller University and organized a new Laboratory of Molecular Biology and Biochem
'"/>

Contact: Joseph Bonner
bonnerj@mail.rockefeller.edu
212-327-8998
Rockefeller University
13-Sep-2003


Page: 1 2 3 4 5 6 7 8

Related biology news :

1. Clay M. Armstrong, MD, wins 1999 Albert Lasker Basic Medical Research Award
2. Gladstone investigator Mike McCune wins prestigious NIH Directors Pioneer Award
3. UT Southwestern biochemist honored with NIH Directors Pioneer Award
4. Award winning researchers reveal potential new role for Glivec
5. UMaine anthropologist wins Solon T. Kimball Award
6. Secretary of Energy announces seven E.O. Lawrence Award Winners
7. Martin Saunders to receive the James Flack Norris Award
8. Berkeley Lab soil scientist Margaret Torn receives Presidential Early Career Award
9. NJIT professor receives Presidential Award for breakthrough research with adult stem cells
10. Second call for proposals for the European Young Investigator Award
11. Virginia Tech professor honored with DeLaval Award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... SEATTLE , April 5, 2017  The Allen ... the Allen Cell Explorer: a one-of-a-kind portal and dynamic ... large-scale 3D imaging data, the first application of deep ... edited human stem cell lines and a growing suite ... the platform for these and future publicly available resources ...
(Date:3/30/2017)... 2017  On April 6-7, 2017, Sequencing.com will host ... hackathon at Microsoft,s headquarters in Redmond, ... on developing health and wellness apps that provide a ... Genome is the first hackathon for personal genomics ... companies in the genomics, tech and health industries are ...
(Date:3/27/2017)... 2017  Catholic Health Services (CHS) has been ... (HIMSS) Analytics for achieving Stage 6 on the ... In addition, CHS previously earned a place in ... electronic medical record (EMR). "HIMSS Analytics ... EMR usage in an outpatient setting.  This recognition ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... New York, NY (PRWEB) , ... October 12, ... ... York Academy of Sciences today announced the three Winners and six Finalists of ... Awards are given annually by the Blavatnik Family Foundation and administered by the ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... United States multicenter, prospective clinical study that demonstrates the accuracy of the ... of identifying clinically significant acute bacterial and viral respiratory tract infections by ...
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, a global contract ... to improve patient outcomes and quality of life, will now be offering its ... attributed to new regulatory requirements for all new drug products, including the finalization ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO and chief ... ), Inc. has been selected for membership in ARCS Alumni Hall of ...
Breaking Biology Technology:
Cached News: