HOME >> BIOLOGY >> NEWS
Learning how cell's tiny motor powers its mobility

Researchers have for the first time shown how the world's smallest moving machines generate the motion needed to transport their chemical cargo throughout cells. The discovery of how one tiny component of the motor protein kinesin powers its movement represents an important insight into one of the most fundamental aspects of biology.

"All cells are churning with internal motion, which involves transport of materials from one place in the cell to another," said Howard Hughes Medical Institute investigator Ronald Vale of the University of California, San Francisco. "It's like trafficking goods within a city. These goods include chromosomes during cell division, and transport of membranes or proteins within cells.

"The kinesin motors responsible for this transport are the world's smallest moving machines, even the smallest in the protein world," he said. "So, besides their biological significance, it's exciting to understand how these very compact machines -- many orders of magnitude smaller than anything humans have produced -- have evolved that ability to generate motion."

Basically, the kinesin protein links with another kinesin to form a two-molecule ferry that moves cellular cargo along tram tracks composed of infinitesimal filaments called microtubules that criss-cross the cell's interior.

In the December 16, 1999, issue of the journal Nature, Vale and his colleagues describe how they analyzed the motion of individual kinesin molecules, ultimately pinpointing the portion of the kinesin protein responsible for generating movement.

The researchers' analyses showed that a tiny piece of the kinesin protein dubbed the "neck linker" abruptly stiffens like Velcro® zipping up when the energy molecule ATP attaches to kinesin. This stiffening throws the neck linker forward and provides the mechanical force that puts the kinesin molecule in mo
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
15-Dec-1999


Page: 1 2 3

Related biology news :

1. Clemson launches S.C. DNA Learning Center
2. Learning opportunities expand using GIS data
3. Learning how organs tell left from right
4. Learning is growing: scientists investigate the links between memory and brain development
5. Jefferson Scientists Find Link Between Learning And Preventing Alzheimers
6. Williams Syndrome: UD Research Pinpoints Language And Learning Traits Of Those With The Disorder
7. Learning To Feel Chronic Pain
8. Learning About Evolution Critical For Understanding Science
9. Uterine Environment Boosts Learning Ability In Mouse Offspring
10. Carnegie Mellon Researchers Say Direct Instruction, Rather Than "Discovery Learning" Is Best Way To Teach Process Skills In Science
11. Learning From Birds And Bees: Engineers Study Insects For Ideas On Tiny "Micro Air Vehicles"

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: