HOME >> BIOLOGY >> NEWS
Lifestyle Determinants Of Plasma Homocysteine

We report on the location and skewness of the distribution of plasma total homocysteine (tHcy) according to lifestyle indexes in 11,941 apparently healthy participants of the Hordaland Homocysteine Study. Most subjects were in two age groups: 9165 subjects were aged 40--42 y and 2351 subjects were aged 65--67 y. The remaining 425 subjects were of intermediate ages. In multivariate analysis, sex, age, folate intake, smoking status, and coffee consumption were the strongest determinants of tHcy concentration. The combined effect of the three modifiable factors was larger than the effect from each factor alone. A lifestyle profile characterized by low folate intakes, smoking, and coffee consumption was associated with a high median tHcy concentration and a pronounced skewness toward high tHcy values. In subjects characterized by a contrasting lifestyle profile [high folate intakes, nonsmoking status, and low coffee consumption (<1 cup/d)], tHcy values were almost normally distributed and the median concentration was 3.0--4.8 µmol/L lower. Among all 40--42-y-old subjects, the 95% reference ranges based on geometric mean tHcy concentrations were 5.1--16.5 µmol/L for women and 6.2--18.7 µmol/L for men. The corresponding ranges for subjects characterized by high folate intakes, nonsmoking status, and low or moderate coffee consumption (<5 cups/d) were 4.8--12.8 µmol/L and 6.2--14.7 µmol/L. These findings are relevant for establishing adequate reference ranges for tHcy and emphasize folate intake, smoking status, and coffee consumption as major acquired determinants of tHcy concentration in this general population. Am J Clin Nutr 1998;67:263-70.


'"/>

Contact: Lorali Barber
lbarber@ascn.faseb.org
301 530-7038
American Journal of Clinical Nutrition
1-Feb-1998


Page: 1

Related biology news :

1. Why some animals have smaller eyes: Lifestyle matters
2. Lifestyle accounts for difference in chimp, human genome
3. Lifestyle changes clinically effective
4. Lifestyle factors fuel high diabetes risk in African-American women
5. Gene Influences How Lifestyle Affects Blood Cholesterol
6. Colon Cancer Linked To Genes, Not Lifestyle
7. Dietary Determinants Of Iron Stores In A Free-Living Elderly Population: The Framingham Heart Study
8. Plasma DHA declines more rapidly postpartum in lactating than in nonlactating women
9. American Heart Association Comment: The Effect Of Folic Acid Fortification On Plasma Folate And Total Homocysteine Concentrations
10. Structure Of The Plasma Membrane Proton Pump Offers A First Glimpse Of The Mechanism Of Ion Pumping Across Membranes
11. Coffee Consumption And Inadequate Dietary Protein Related To Serum Homocysteine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: