"Here, for instance, are some quite specific data on the way in which weight loss and exercise can alter body chemistry, so as to favor a reduction in risk. This adds to the empirical findings of lower risk of cancer with healthier lifestyles that can act as a spur to those who need to know how it works before they are willing to change," he added.
The Effects of Weight Loss and Weight Gain on Biomarkers of Breast Cancer Risk (Abstract 1451)
Pre-menopausal weight gain is associated with an increased risk of post-menopausal breast cancer, according to researchers from Manchester, England, who examined a weight-loss program to identify the link between weight loss and risk of developing cancer. Results showed that even a small weight loss, just five percent of an individual's body weight, may lower the risk of developing breast cancer. In the trial, 79 women with a family history of breast cancer who had gained significant amounts of weight as adults were divided into two different diet regimens: a calorie-restricted/exercise, weight-loss program; and a standard diet with only exercise advice.
Changes were measured by body weight, waist circumference, percent body fat, total subcutaneous and intrabdominal fat, insulin, testosterone and SHGB (sex hormone binding globulin), which impacts levels of bioavailable estrogen. The e
Contact: Aimee Frank
American Association for Cancer Research