Lilly Endowment grants almost $26 million to Purdue Discovery Park

enes of living organisms and then figuring out how those thousands of genes function. This would show how cells are regulated and respond to chemicals, mutations, environmental stimuli, age, disease and pathogens.

Genomics research offers promise in many areas, from improving the disease resistance of plants and animals, to saving endangered wildlife and increasing the production of certain crops that require fewer pesticides.

"Many Purdue faculty are making advances based upon genomics," Jischke said. "Genomics is enabling the development of corn, soybeans and wheat that can withstand the stresses of severe weather. Genomics advancements allow faculty to understand pollination processes to produce better crops."

The bioscience/engineering center also will connect researchers in the life sciences with engineers in the nanotechnology center. Researchers in medicinal chemistry, electrical engineering and other fields already are at work designing devices and electronic chips that will use DNA to quickly detect substances in the blood, air or in food.

The center will focus initially on the interdisciplinary fields of biomedical engineering and proteomic analysis.

One focus of biomedical engineering will be "tissue engineering," creating materials from animal tissue that can promote healing in people. These products now are being used to treat urinary incontinence in women, repair internal organs and damaged ligaments, and cure skin wounds and chronic sores. Two Indiana companies hold licenses from Purdue to develop the technology.

Proteomics involves identifying and studying proteins formed in living systems when specific genes are activated. The main objective of this work will be to create a new generation of devices in the next decade that will allow the nearly instantaneous analysis of up to 500,000 components in living cells.

The work has many potential applications. For example, these instruments might be

Contact: Jeanne Norberg
Purdue University

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