HOME >> BIOLOGY >> NEWS
Long-QT syndrome

Molecular autopsy finds that a genetic heart condition may be the cause of many unexplained drownings

ROCHESTER, MINN. -- According to a study by Mayo Clinic pediatric cardiology and pathology specialists published in this week's edition of New England Journal of Medicine, a genetic defect known as long-QT syndrome may be the cause of many unexplained drownings.

Drowning kills more than 4,000 children and young adults each year. Drowning is second only to motor vehicle accidents as the leading causes of accidental death in children and young adults. Many drownings are attributed to lack of supervision, alcohol or drug abuse, trauma and seizures. However, each year, more than 400 drownings involving children and young adults have no explanation.

"The study proves for the first time that an unexplained drowning could be caused by a genetic defect that affects the heart's rhythm," says Michael Ackerman, M.D., Ph.D., a Mayo Clinic pediatric cardiologist and principal investigator of the study. "In a case study of a 19-year-old woman who died after a near-drowning, we were able to prove through molecular testing, that she had long-QT syndrome. And since the genetic defect runs in families, we were able to test family members and offer preventive treatment to other family members who also have the defect."

Long-QT syndrome is a genetic condition that affects the heart's electrical system. In patients with long-QT syndrome, the heart takes longer to reset, or re-charge itself between each beat. Usually, patients have no problem with this condition, but certain triggers like swimming, intense physical exertion, or being suddenly startled or frightened can set it off, causing fainting spells, seizures or even death from a fatal heart rhythm called ventricular fibrillation.

Dr. Ackerman and his colleagues investigated the cause of death of the 19-year-
'"/>

Contact: Chris Gade
newsbureau@mayo.edu
507-284-2511
Mayo Clinic
6-Oct-1999


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Rare childhood genetic syndrome identified
3. Veterans with Gulf War syndrome have damage in specific, primitive portion of nervous system
4. Last of known genes identified in complex obesity syndrome
5. Scientist who discovered Sly syndrome finds new research path to explore for treating the disease
6. Babies with DiGeorge syndrome saved by immune supression, thymus transplant
7. Gene discovered for Cornelia de Lange syndrome, a disabling genetic disease
8. From algae, weeds and people: new genetic clues to complex obesity syndrome
9. Cellular problems found behind complex obesity syndrome
10. Surgeons explore new treatment for Tourette syndrome
11. Researchers identify a new form of disease gene associated with Rett syndrome

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/10/2020)... Va. (PRWEB) , ... July 08, 2020 , ... ... Latest on Cell and Gene Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, ... need a comparability study, but what is the most effective way to complete ...
(Date:7/2/2020)... ... July 02, 2020 , ... Dutch ... the use of its revolutionary NEXTGENPCR endpoint thermocycler to test for SARS-CoV-2 ... The article, titled "Ultra-fast one-step RT-PCR protocol for the detection of SARS-CoV-2," ...
(Date:6/28/2020)... JUPITER, Fla. (PRWEB) , ... June 25, 2020 , ... ... will focus on innovations in accelerated Point of Care Testing solutions (POCT). Check local ... labs. Samples are collected at medical offices and are shipped to labs throughout the ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... (PRWEB) , ... July 16, 2020 , ... After research ... The completion of a great surgery is only the beginning of a successful study, ... research community. , Join Brad Gien, Global Head of Surgery from Envigo ...
(Date:7/18/2020)... ... 16, 2020 , ... Medial EarlySign , a leader ... of high-burden diseases, and Centric Consulting, a business and technology consulting firm, today ... data in order to identify and prioritize patients for care. , Combining Centric’s ...
(Date:7/10/2020)... Va. (PRWEB) , ... July 08, 2020 , ... ... testing services and products, announces a significant expansion of laboratory operations through its ... collection for agencies implementing testing programs. , Bode-CARES provides a ...
(Date:7/10/2020)... ... July 09, 2020 , ... In most research using ... suppress pigment formation in zebrafish embryos, maintaining optical transparency to facilitate microscopic imaging. ... has been using the zebrafish model to investigate the causes of leukaemia and ...
Breaking Biology Technology:
Cached News: