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Long-Standing Puzzle Of Immune System Is Solved By UCSF Researchers

solved to eliminate the potential mutation.

"The so-called immunoglobulin-mutator system in B cells seems to fool the DNA-repair system into confusing the old, correct DNA strand with the new, incorrect DNA strand, so that the mismatch is resolved by fixing the mutation in place instead of eliminating it," Steinberg says.

The National Institutes of Health and the Arthritis Foundation were the major funders of the study.


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