HOME >> BIOLOGY >> NEWS
Long-term heart damage may result from constant confrontation and defeat

(July 14, 2004) - Bethesda, MD The toughest among us combat soldiers, athletes, or anyone in a high-stress occupation, may claim that they become "hardened" to adversity and defeat. But a new animal study demonstrates that although the body may temporarily adjust to stress, the risk for long-term cardiac problems may be the consequence of daily exposure to confrontation.

Background

Even the most self-controlled individual is susceptible to stress, which is the body's reaction to injurious forces, infections, and various abnormal states that tend to disturb its normal physiological equilibrium. When we exert limited control over environmental stimuli, such physiological and behavioral changes may ultimately produce increased susceptibility to psychosomatic disorders when the brain impacts on bodily functions such as cardiovascular disturbances.

Social stressors have been shown to induce robust short-term activations of the sympathetic-adrenomedullary system and the pituitary-adrenocortical axis. As far as cardiovascular responses to social defeat and subordination are concerned, increases in blood pressure and plasma catecholamine levels (the biochemical response to stress) have been documented in rats, persisting as long as the stimulus was present or shortly thereafter. In addition, experimental stress has produced a considerable increase in heart rate.

Long-term effects of social challenges on a number of physiological and behavioral parameters have also been reported, mainly involving the daily rhythms of heart rate, body temperature, food intake, and exploratory and social activity. Many animal studies indicate that there is a gradual decline in stress when the stress factor, such as changes in habitation, is repeatedly applied. In other words, the body adapts so there is less stress.

However, it was shown recently that rats intermittently exposed to an uncontrollable social stressor (defe
'"/>

Contact: Mayer Resnick
mresnick@the-aps.org
301-634-7209
American Physiological Society
19-Jul-2004


Page: 1 2 3 4

Related biology news :

1. Long-term effects of carbon monoxide poisoning are an autoimmune reaction
2. Long-term effects of embryo culture on behavior studied
3. Long-term natural gas supplies should meet growing demand in coming decades, study finds
4. Long-term decline of coral reef ecosystems reported
5. Long-term study of humans and deforestation in Amazon Basin gets new support
6. Long-term studies show most intersex adults happy with gender assignments at birth
7. Long-term data on Dendreons Mylovenge vaccine presented at American Society of Hematology
8. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
9. Screen siblings, parents of infants with severe heart abnormalities
10. Recent evolution at a single gene may have brought down heart disease risk in some human groups
11. How do you mend a broken heart?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/10/2020)... , ... July 08, 2020 , ... ... Cell and Gene Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, 2020 • ... comparability study, but what is the most effective way to complete one? Will ...
(Date:7/1/2020)... ... 01, 2020 , ... Catalent, a global leader in clinical ... packaging facility in Minakuchi, located in the Shiga prefecture of Japan. , Operating ... the new 60,000-square-foot facility will provide customers with flexible clinical supply solutions, serving ...
(Date:6/23/2020)... Md. (PRWEB) , ... June ... ... leading provider of gene-to-protein and monoclonal antibody development services, today announced that ... protein-based products and services to the pharmaceutical, diagnostics, and research industries. The ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... MIAMI (PRWEB) , ... July 29, 2020 , ... ... nearly 200 of the top radiation centers in 16 countries, has reached its ... years, SDX® is now in routine use at top universities including University of ...
(Date:7/18/2020)... ... July 16, 2020 , ... “We are thrilled to deliver this ... the only technology of its kind on the market and we were pleased that ... protective capacity of traditional cultured ingredients, creating a natural way to extend the shelf ...
(Date:7/10/2020)... ... July 09, 2020 , ... ... Massachusetts Institute of Technology (MIT) has expanded the company’s exclusive license to ... move into the point-of-care diagnostic market, focusing initially on the SARS-CoV-2 biosensor. ...
(Date:7/7/2020)... (PRWEB) , ... July 06, 2020 , ... ... Practices Awards. Entries from Roche, Eli Lilly, Bristol-Myers Squibb, the University of Chicago, ... 2003, Bio-IT World has hosted an elite awards program, highlighting outstanding examples of ...
Breaking Biology Technology:
Cached News: