The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Low-Protein Diet May Reverse Kidney Disease

A very low protein diet with amino acid supplements may cure a severe kidney disease in some people, a Johns Hopkins study shows. The results suggest the dietary therapy should be tried before drug treatment for nephrotic syndrome, a chronic kidney disorder that often leads to kidney failure.

Scientists have not solved the paradox of why eating less protein benefits some patients -- sufferers already lose too much protein in their urine, yet restricting dietary protein may help many sufferers, says Mackenzie Walser, M.D., the study's lead author and a professor of pharmacology, molecular sciences and medicine. The study, which was supported in part by the National Institutes of Health, is published in the September issue of the American Journal of Kidney Diseases.

"Five patients remain virtually cured, while only one patient's blood-protein level worsened, " says Walser.

Hopkins researchers put 16 adults on a very low protein diet with essential amino acid or ketoacid supplements for 10 months. Essential amino acids are those amino acids -- building blocks of protein -- that the body can not make. Ketoacids are slightly modified forms of amino acids.

The disorder gradually disappeared during the next three to 15 months in five participants, who started the study before kidney failure became severe, the results show. Four of the five people have resumed normal or nearly normal diets and have remained in remission or near remission for six months to two years. The other 11 participants, who had more advanced kidney failure before starting the study, showed temporary improvement, but all eventually went on dialysis.

Nephrotic syndrome usually is treated with drugs and only modest reduction of dietary protein to reduce the loss of protein in the urine. Severe protein restriction has been avoided for fear of aggravating the low levels of protein in the blood.

In contrast with other treatments, such as steroids or immunosuppressive drugs, the dietary
'"/>

Contact: John Cramer
jcramer@welchlink.welch.jhu.edu
410-955-1534
Johns Hopkins Medical Institutions
1-Sep-1996


Page: 1 2

Related biology news :

1. Reverse-direction movement of a molecular motor
2. Reverse CPR performed on back could better restore blood flow
3. Key Peptides Found That Stop -- Even Reverse -- Kidney Disease In Lupus
4. Penn Researchers Develop Gene Therapy Technique That Reverses Muscle Membrane Weakness In Muscular Dystrophy Variant
5. New Retinal Surgery May Reverse Legal Blindness
6. Two-Pronged Attack On Immune System Cells Engineered By HIV Gene vpr: Effects Markedly Reversed By Antisteroid Compound RU-486
7. Kidney injurys harmful effects on bones blocked in mice
8. A Versatile Signal In Vertebrate Embryogenesis: Wnt-4 Regulates Kidney Development, Sex Organ Differentiation, Neuronal Survival And Axonal Guidance
9. Cells From Mother Can Boost Success Of Sibling-To-Sibling Kidney Transplants
10. University Of Texas Southwestern Researchers Develop New Test For Kidney Function
11. Lack Of Intestinal Bacterium Linked To Kidney Stones In Cystic Fibrosis Patients, University Of Florida Researchers Report

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Low Protein Diet May Reverse Kidney Disease

(Date:11/22/2009)...dren exposed prenatally to tobacco smoke and durin...for ADHD, according to research done at Cincinnati... estimates that up to 35 percent of ADHD cases in ...uced by eliminating both of these environmental ex...hildren , "Tobacco and lead exposure each have ...
(Date:11/22/2009)... November 18, 2009 -- A butterfly,s proboscis look...ing -- but it works more like a paper towel, accor...e hopes to borrow the tricks of this piece of inse...e fluid inside of cells. , Kornev will present h...e American Physical Society,s (APS) Division of Fl...
(Date:11/20/2009)... are at work on many scientific and technological ...ently provided support that totals nearly $4.3 mil...stigators under the American Recovery and Reinvest... awarded grants for investigation of solar phenome...ysics, will enhance the capabilities of NJIT,s Big...
Breaking Biology News(10 mins):Exposure to lead, tobacco smoke raises risk of ADHD 2NJIT receives NSF funding to improve Big Bear Telescope, study solar energy 2Warady 26amp 3B Davis LLP Named One of 26apos 3BTop 50 Employers for Generation Y Chicago 26apos 3B 60302 1Warady 26amp 3B Davis LLP Named One of 26apos 3BTop 50 Employers for Generation Y Chicago 26apos 3B 60302 2Warady 26amp 3B Davis LLP Named One of 26apos 3BTop 50 Employers for Generation Y Chicago 26apos 3B 60302 3Data Presented on Cempra Pharmaceuticals CEM 101 at the Infectious Diseases Society of America Annual Meeting Reinforces Potency and Coverage Against 5810 1Data Presented on Cempra Pharmaceuticals CEM 101 at the Infectious Diseases Society of America Annual Meeting Reinforces Potency and Coverage Against 5810 2Board of Directors Declares Cash Distributions 60297 1Board of Directors Declares Cash Distributions 60297 2
(Date:11/23/2009)...sts of a two-dimensional carbon layer in which the... resembling a honeycomb. Carbon nanotubes are roll...ene sheets form graphite. Graphene boasts some ver...sistant, an excellent thermal conductor, and recon...d ductility. In addition, graphene is impermeable ...
(Date:11/23/2009)...UGA,ON,Nov.23/PRNewswire-FirstCall/-YMBioSciencesI...elopmentcompanythatidentifiesandadvancesadiversepo...tagesofdevelopment,todayreportedthatCytopia(ASX:CY...gCYT387,apotent,orally-administeredJAK1/JAK2inhibi...r,Minnesota.AproposaltomergeCytopiaintoYMhasbeenpr...
(Date:11/23/2009)... Contec’s Sporicidin disinfectant s...tal-grade disinfectants against H1N1 and Influenza...RWEB) November 24, 2009 -- Contec Inc, the leading...ced that their Sporicidin disinfectants have bee...enza A viruses, including Pandemic 2009 H1N1 influ...
(Date:11/23/2009)...BC,Nov.23/PRNewswire/-InimexPharmaceuticals,Inc.an...asitsPresidentandCEO. ,, Abramsbringsmorethan25...ex.Heisaco-inventorofthenuclearmedicineimagingagen...ey,plcwherehewasManager,BiomedicalResearchWorldwid...ey,BCandwasPresidentandCEOfrom1996to2006.AnorMEDdi...
Breaking Biology Technology:Polymer with honeycomb structure 2YM BIOSCIENCES REPORTS FIRST PATIENT IN PHASE I/II TRIAL OF JAK1/JAK2 INHIBITOR, CYT387 ENROLLED BY CYTOPIA 2YM BIOSCIENCES REPORTS FIRST PATIENT IN PHASE I/II TRIAL OF JAK1/JAK2 INHIBITOR, CYT387 ENROLLED BY CYTOPIA 3YM BIOSCIENCES REPORTS FIRST PATIENT IN PHASE I/II TRIAL OF JAK1/JAK2 INHIBITOR, CYT387 ENROLLED BY CYTOPIA 4Sporicidin Brand Disinfectant Kills H1N1 in 3 Minutes 2Inimex Announces Appointment of New CEO 2
Other News:
.The pacemaker has taken on an increasingly important role in recent years. Originally used to fix electrical abnormalities in people with irregular heart rhythms, it is now in favor for heart failur
...reakthrough that could affect the more than 50 mil...a, researchers at Northwestern University and Harv...f the interaction complex of two molecules that ar...he discovery of how the antibody binds to the mast...
...-- Dr. Michael Kuhar and a team of neuroscientists... Emory University have found that a naturally occu...ed with cocaine and methamphetamine. The finding s... (Cocaine- and Amphetamine-Regulated Transcript) p...
...ction of novel genes uncovered in genome sequencin...e formation of a Center for Comparative Functional...te-of-the-art tools of biology, mathematics and co...genes that are being uncovered in genome sequencin...
Heart failure patients with worst heart function are good candidates for pacemakers 2Molecular structure key to allergies and asthma is identified 2Molecular structure key to allergies and asthma is identified 3Brain contains cocaine-like chemical 2NYU announces establishment of a center for comparative functional genomics 2
...DNA Fingerprinting at the University of Leicester,...th a prestigious international accolade later this...s Royal Society Wolfson Research Professor in the ...P. Heineken Prize for Biochemistry and Biophysics ...
...ve long been promised a male version of the female...ceptive to market may not be hormonal at all. .......n approval today for a 90-man study of the Intra V...stops sperm in their tracks. The study, to take pl...
...---A gene that degrades the body's collagen infras...nd expand girth.......Excess fat is stored in whit...body, primarily around the midsection. The gene st...etabolic scissors, cutting through the collagen ti...
... Diabetes Center, the global leader in diabetes re...nership with Providence Hospital in Southfield and...urbs of Detroit, MI. Providence Hospital is part ...outheast Michigan. The Joslin Diabetes Center Affi...
Eminent inventor of DNA fingerprinting gains new recognition 2Eminent inventor of DNA fingerprinting gains new recognition 3New male contraceptive targets sperm, not hormones 2Expanding waistlines triggered by your genes 2Joslin Diabetes Center partners with St. John Health's Providence hospital in Michigan 2