Low doses of radiation in nature may pose more risk

NEW YORK, NY Radiation can trigger widespread mutations in living cells at much lower doses than the amount scientists previously believed could do such damage, according to findings from a study by Columbia researchers. The research may help public health officials reconsider what levels of radiation in nature should be deemed safe.

Led by professor of radiation oncology and public health Dr. Tom K. Hei, the study found that a dose that strikes as few as one in 10 cells has nearly the same mutagenic (mutation-causing) effect as a dose that strikes every cell. The added damage occurs, the researchers say, because of what is called the bystander effect, in which injured cells send aberrant signals to neighboring cells. The study is to be published in the Dec. 4th issue of the Proceedings of the National Academy of Science.

The researchers found the bystander effect occurs with alpha particles, a common type of radiation that comes from sources such as nuclear explosions, plutonium, and radon, a naturally occurring gas that seeps into many homes.

In the National Cancer Institute-funded study, the researchers beamed a single alpha particle through the nuclei of randomly selected cells growing in petri dishes. Alpha particles consist of the nuclei, or cores, of helium atoms. The radiation was equivalent to a dose below 20 centiGrays.

A centiGray is a unit used in radiation measurement. The radiation employed in the study is considered low-level. Mine workers are occasionally exposed to such levels of radiation. People in radon-contaminated homes are rarely exposed to these levels. The risks of exposure to lower radiation levels are poorly understood and have been the subject of controversy for decades.

In the study, the researchers found that when they beamed alpha particles at only one in 10 cells, the results were almost the same as if they had be

Contact: Annie Bayne
Columbia University Medical Center

Page: 1 2 3

Related biology news :

1. Vioxx in high doses causes hypertension
2. PTEN and prostate cancer--the devil is in the doses
3. Research shows high doses of acetaminophen clear rapidly and consistently from bloodstream
4. UT Southwestern researchers say overdoses of acetaminophen cause most cases of acute liver failure
5. Extended-release niacin effective in low doses for diabetics, say UT Southwestern researchers
6. Gel may cut doses for some medications
7. New evidence of radiation risk in childhood leukaemia
8. Chernobyl study: Risk of thyroid cancer rises with radiation dose
9. Many physicians misperceive radiation risks to developing fetuses from X-rays and CT scans
10. New insight into how tumors resist radiation
11. Ultraviolet irradiation in ventilation systems could reduce office sickness

Post Your Comments:

(Date:8/3/2020)... ... August 03, 2020 , ... Accumen Inc. ... with medical equipment manufacturer, Spectrum Solutions, to provide COVID-19 saliva testing kits nationally. ... supply chain for more than 10 years. Early in the COVID-19 crisis, we ...
(Date:7/18/2020)... ... 17, 2020 , ... Commercial launch readiness is a critical stage in a ... cure or vaccine, the global economic downturn will only increase price pressures overall for ... and capturing full value from every product launch is critical. However, history shows that ...
(Date:7/2/2020)... , ... July 02, 2020 ... ... Systems, B.V. (MBS) has announced a publication detailing the use of its ... transcription polymerase chain reaction (RT-PCR) in 16 minutes. The article, titled "Ultra-fast ...
Breaking Biology News(10 mins):
(Date:7/7/2020)... ... 2020 , ... R3 International is now offering stem cell therapy for Alzheimers ... Depending on the patient's condition, treatment may be offered IV, intrathecal or with a ... of Alzheimers dementia, and the incidence continues to increase as individuals live longer. There ...
(Date:7/1/2020)... ... June 29, 2020 , ... ... of 40% in 2020, despite many obstacles created as a result of COVID-19. ... revenue for its partnered medical practices and medical manufacturers by expanding access to ...
(Date:7/1/2020)... ... June 30, 2020 , ... ... data insights, today announced that the launch of a new clinical ... data about the tumor microenvironment (TME). , “Flagship’s TissueInsight is a service ...
(Date:6/28/2020)... SAN JOSE, Calif. (PRWEB) , ... June 25, ... ... the globe, researchers are racing to develop a vaccine or drug treatment. In ... company Recursion has publicly released the world’s largest imaging dataset portraying ...
Breaking Biology Technology:
Cached News: