HOME >> BIOLOGY >> NEWS
Lupus Research Institute awards $3 million in novel research grants to further new science in lupus

ersity of Pennsylvania, Philadelphia
APOPTOTIC NUCLEOSOMAL DNA AND ITS RELEVANCE IN SLE. Dr. Caricchio's research focuses on an important autoantigen in lupus, called nucleosome. Recent evidence suggests that nucleosomes are derived from a process called programmed cell death or apoptosis, and that such process may be the primary supplier of autoantigens for SLE, making apoptosis a potentially robust therapeutic target. This study aims to confirm the exact role that apoptotic nucleosomes play in the cause of SLE and pinpoint the source of this dangerous material. This work may provide a stronger rationale for targeting new therapies at apoptotic nucleosome.

  • Robert M. Clancy, PhD, New York University School of Medicine, Hospital for Joint Diseases, New York
    CIRCULATING ENDOTHELIAL CELLS, A BIOMARKER TO PREDICT SUBCLINICAL ATHEROSCLEROSIS IN PATIENTS WITH SLE. Dr. Clancy's research project will examine the relationship between circulating endothelial cells and the onset of atherosclerosis in lupus. These cells are activated by immune stimuli and are potential participants in the inflammatory process that contributes to tissue damage and atherosclerosis. Using a large patient base, Dr. Clancy's study will test this intriguing idea which could lead to a new therapy.

  • Mary K. Crow, MD, Hospital for Special Surgery, New York
    BIOMARKERS OF DISEASE FLARE IN SLE. A previous LRI grant recipient, Dr. Crow will examine several new candidate biomarkers that may reflect lupus flares. One set of potential biomarkers includes interleukin 8 (IL-8) and the interleukin 8 receptor. The second potential biomarker is an uncharacterized gene product with sequence similarity to regulators of RNA processing. Confirmation of either of these candidate genes will give us the ability to predict lupus flare and will advance testing of new therapies in patients.

  • Anne Davidson, MD, Albert Einste
    '"/>


  • Contact: Lydia Dorsky
    ldorsky@lupusny.org
    212-685-4118
    Lupus Research Institute
    16-Jun-2004


    Page: 1 2 3 4 5 6

    Related biology news :

    1. Lupus study finds abnormal alpha-interferon secretion may lead to better therapies for immune-system disease
    2. Key Peptides Found That Stop -- Even Reverse -- Kidney Disease In Lupus
    3. Researchers determine genetic cause of Timothy syndrome
    4. Researchers find color sensitive atomic switch in bacteria
    5. Schepens Eye Research Institute receives Roadmap grant to develop center for curing eye diseases
    6. Researchers identify protein promoting vascular tumor growth
    7. Researchers devise potent new tools to curb ivory poaching
    8. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
    9. Researchers ID chlorophyll-regulating gene
    10. Environmental issues center of Inland Northwest Research Alliance 4th Annual Symposium
    11. Research suggests new avenue for stopping, preventing colon cancer

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:8/26/2020)... ... August 25, 2020 , ... ... in partnership with Essex Bio-Technology, a bio-pharmaceutical company specializing in Ophthalmology and ... study of SkQ1 ophthalmic solution in patients with moderate to severe Dry ...
    (Date:8/26/2020)... ... ... Modality Solutions, a biopharmaceutical cold chain validation engineering firm, is ... is the most prestigious ranking of the nation’s fastest-growing private companies. Modality Solutions made ... three-year revenue growth of 71 percent. , The Inc. 5000 list represents a ...
    (Date:8/21/2020)... ... August 18, 2020 , ... Sentien Biotechnologies, ... that the U.S. Food and Drug Administration (FDA) has approved the company’s Investigational ... the treatment of severe COVID-19. Approval of this IND allows Sentien to initiate ...
    Breaking Biology News(10 mins):
    (Date:7/31/2020)... BEDFORD, Mass. (PRWEB) , ... July 29, 2020 ... ... of highly reliable, solid-state radar transmitter systems that can be configured to drive ... a single controller that can drive one or two switches in a push-pull ...
    (Date:7/31/2020)... (PRWEB) , ... July 29, 2020 , ... ... 200 of the top radiation centers in 16 countries, has reached its 20th ... SDX® is now in routine use at top universities including University of Pennsylvania, ...
    (Date:7/18/2020)... ... July 16, 2020 , ... “We are thrilled to deliver this new technology ... technology of its kind on the market and we were pleased that the IFT ... of traditional cultured ingredients, creating a natural way to extend the shelf life and ...
    (Date:7/10/2020)... ... July 09, 2020 , ... ... Technology (MIT) has expanded the company’s exclusive license to include clinical applications ... point-of-care diagnostic market, focusing initially on the SARS-CoV-2 biosensor. CANARY’s™ fast ...
    Breaking Biology Technology:
    Cached News: