HOME >> BIOLOGY >> NEWS
Lupus Research Institute awards $3 million in novel research grants to further new science in lupus

rotein that tightly interacts with DNA in the disease process. In this study, researchers will examine how this protein receptor binds with DNA and whether dysfunctional DNA binding is an important factor in triggering lupus.

  • Elahna Paul, MD, PhD, Massachusetts General Hospital, Harvard Medical School, Boston
    IMMUNO/RENAL INTERFACE IN MURINE LUPUS GLOMERULONEPHRITIS. By studying a mouse model of lupus glomerulonephritis, Dr. Paul will learn how kidney cells react to an autoimmune attack. She will examine early kidney lesions before clinical signs of the disease are present, with the goal of predicting the development of kidney disease in lupus patients.

  • David S. Pisetsky, MD, PhD, Duke University Medical Center, Durham
    ROLE O HMGB1 (HIGH MOBILITY GROUP PROTEIN) IN THE PATHOGENESIS OF SLE. Dr. Pisetsky's research will focus on a protein called HMGB1 that serves two functions in the body. Inside the cell, HMGB1 exists in the cell nucleus and binds DNA. Outside the cell, HMGB1 stimulates inflammation. Dr. Pisetsky will determine the process by which this protein is released into the blood when cells die and the mechanisms by which HMGB1 can stimulate an autoimmune response, and then he will determine whether HMGB1 may serve as a biomarker for lupus because of its association with inflammation and cell death. In addition, this work will uncover whether HMGB1 can be a target of therapy.

  • Luminita Pricop, MD, Hospital for Special Surgery, New York
    GENETIC AND ACQUIRED MODIFIERS OF APC FUNCTION IN SLE. Dr. Pricop's extremely novel research concept focuses on the role of inhibitory Fc receptors, a gene associated with lupus, in stimulating B and T cells. Her investigations will look at the mechanism that leads immune complexes to stimulate B and T cells, which could characterize new genetic markers for lupus.

  • Chander Raman, PhD, University of Alabama
    '"/>


  • Contact: Lydia Dorsky
    ldorsky@lupusny.org
    212-685-4118
    Lupus Research Institute
    16-Jun-2004


    Page: 1 2 3 4 5 6

    Related biology news :

    1. Lupus study finds abnormal alpha-interferon secretion may lead to better therapies for immune-system disease
    2. Key Peptides Found That Stop -- Even Reverse -- Kidney Disease In Lupus
    3. Researchers determine genetic cause of Timothy syndrome
    4. Researchers find color sensitive atomic switch in bacteria
    5. Schepens Eye Research Institute receives Roadmap grant to develop center for curing eye diseases
    6. Researchers identify protein promoting vascular tumor growth
    7. Researchers devise potent new tools to curb ivory poaching
    8. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
    9. Researchers ID chlorophyll-regulating gene
    10. Environmental issues center of Inland Northwest Research Alliance 4th Annual Symposium
    11. Research suggests new avenue for stopping, preventing colon cancer

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:7/18/2020)... ... ... Commercial launch readiness is a critical stage in a product life cycle. While ... global economic downturn will only increase price pressures overall for the industry. The era ... from every product launch is critical. However, history shows that only a third of ...
    (Date:7/2/2020)... ... 01, 2020 , ... AltruBio Inc. http://www.altrubio.com , a ... for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European Hematology Association ... of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase 1 single ...
    (Date:6/28/2020)... ... June 25, 2020 , ... Genedata, ... that it has entered into a multi-year contract with Merus N.V., a ... translational and clinical research strategy to discover and develop ground-breaking drugs. The ...
    Breaking Biology News(10 mins):
    (Date:7/31/2020)... Mass. (PRWEB) , ... July 29, 2020 , ... ... wire that can combine up to three different materials for use with CRM, ... combine up to three materials to meet specific design requirements, performance, and cost ...
    (Date:7/31/2020)... ... July 30, 2020 , ... ... today announced the release of its signature product called Beacon - a ... and other field medical professionals. , Beacon helps MSLs streamline communication ...
    (Date:7/18/2020)... ... July 16, 2020 , ... ... the early detection and prevention of high-burden diseases, and Centric Consulting, a business ... healthcare organizations to utilize existing data in order to identify and prioritize patients ...
    (Date:7/10/2020)... ... 2020 , ... In most research using the zebrafish model, ... in zebrafish embryos, maintaining optical transparency to facilitate microscopic imaging. Over the past ... the zebrafish model to investigate the causes of leukaemia and its relationship with ...
    Breaking Biology Technology:
    Cached News: