HOME >> BIOLOGY >> NEWS
Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better

Geneva, Switzerland: A study by Dutch and German researchers has provided evidence that lycopene may be able to inhibit the growth of prostate tumours and that its effect may be enhanced if it is combined with vitamin E.

A number of epidemiological studies have already indicated that high intake of lycopene a carotinoid that gives the red colour to tomatoes and other fruits is associated with a reduced risk of prostate cancer.

But, these observational findings have now been underpinned by new research demonstrating a beneficial effect in human prostate tumours grown in mice. A Phase II study testing the compounds in cancer patients is now under way.

The findings of the animal study are being reported by Dutch research scientist Dr. Jacqueline Limpens at the EORTC-NCI-AACR[1] Symposium on Molecular Targets and Cancer Therapeutics in Geneva.

The study involved testing one low and one high dose of synthetic lycopene alone, one low and one high dose of synthetic vitamin E alone and a combination of low dose synthetic lycopene and vitamin E or a placebo. The researchers injected human tumour cells into the prostate of mice to see what effect the lycopene and vitamin supplements would have on the tumour growth and PSA (prostate specific antigen)[2] and to compare any effects against the placebo.

Dr. Limpens, who is from the Department of Urology at the Josephine Nefkins Institute at the Erasmus Medical Center in Rotterdam, said: "We found that low dose lycopene suppressed the growth of the human prostate tumours by over half (at day 42 of the study), extending the tumour doubling time accordingly, while all other single treatments had no significant effect. However, the combination of low-dose lycopene and vitamin E produced the greatest tumour inhibition 73% (at day 42). Importantly, we also saw that the doubling time of PSA values matched the tumour responses in all the experimental groups. This means that we can use PSA value
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
41-227-612-205
European Organisation for Research and Treatment of Cancer
30-Sep-2004


Page: 1 2 3

Related biology news :

1. Lycopenes anti-cancer effect linked to other tomato components
2. Slow-moving ground water slows down water-quality improvements in Chesapeake Bay
3. Cellular fat sensor slows heart disease
4. Ocean plant life slows down and absorbs less carbon
5. Gene therapy prolongs survival, slows disease progression in ALS mice
6. Even in middle age, cutting calories slows aging of the heart
7. Study suggests coenzyme Q10 slows functional decline in Parkinsons disease
8. Networking slows down protein evolution, study reveals
9. Alcohol-intoxication slows bodys efforts to restore normal blood pressure after small blood loss
10. UT Southwestern researchers discover how common MS drug slows progression of the disease
11. Alcohol researchers show friendly virus slows HIV cell growth

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2019)... GALWAY, Ireland (PRWEB) , ... April 02, 2019 ... ... discovery, development and commercialization of first-in-class stromal cell immunotherapies, announced it will move ... to become the anchor tenant at the University’s newly created biotechnology park in ...
(Date:4/4/2019)... ALISO VIEJO, Calif. (PRWEB) , ... April 02, ... ... a leading clinical genetics testing company, will present results demonstrating that RNA genetic ... hereditary cancer genetic testing. This study, awarded as a Top Rated poster, is ...
(Date:4/1/2019)... ... April 01, 2019 , ... uBiome announces ... Related Conditions” by the US Patent and Trademark Office on January 1, 2019 ... by uBiome collaborators Dr. Zachary Apte, Dr. Daniel Almonacid, Dr. Jessica Richman, ...
Breaking Biology News(10 mins):
(Date:4/10/2019)... , ... April 10, 2019 , ... After more than ... The new kitchen is equipped with updated appliances and modern lighting and fixtures, ... Jolla-based venue. , “We’ve seen tremendous growth in the demand for our ...
(Date:4/9/2019)... ... , ... Sonny Bar Lisa, or Sonny for short, is a quarter horse ... a series of diagnostics, an MRI was performed which revealed Sonny had torn his ... found that VetStem Regenerative Cell Therapy may be a treatment option for ...
(Date:4/8/2019)... and BOSTON (PRWEB) , ... April 08, 2019 ... ... cloud-based enterprise-class unified communications and collaboration solutions, announced today the launch of their ... to an unprecedented range of business and contact-orientated applications while using CT Cloud ...
(Date:4/8/2019)... ... April 09, 2019 , ... To support the global ... Zuckerberg Biohub (CZ Biohub) has chosen Geneious Biologics to help them analyze and ... Biohub’s efforts to establish new approaches to inform the discovery of antibody-based diagnostics, ...
Breaking Biology Technology:
Cached News: