HOME >> BIOLOGY >> NEWS
MIT tool impacts multi-billion dollar drug

CAMBRIDGE, Mass.-- MIT scientists and colleagues announce work that could impact the multi-billion dollar heparin industry and change how the FDA regulates that common anti-clotting drug. The work is the first application of a novel analytical tool announced by the same core group of researchers last fall. Other important applications promise to follow.

"Periods of great discovery in science are almost always preceded by the development of new tools," writes Professor Matthew A. Nugent of Boston University in the September 12 issue of the Proceedings of the National Academy of Sciences. His commentary accompanies two articles by the MIT researchers describing the heparin work.

MYSTERIOUS WORLD
The new analytical tool probes the mysterious world of complex sugars. Although these compounds have recently been shown to play important roles in processes from viral infection to tissue development, "the field has lagged far behind the mainstream work on proteins and DNA," said Ram Sasisekharan, an associate professor in the Division of Bioengineering and Environmental Health (BEH) and leader of the MIT team.

Thats because the complex sugars have many more building blocks than their better-known cousins, DNA and proteins, making them more difficult to study. The MIT tool is a quick, easy way to determine the structure, or order of building blocks, in these sugars (MIT Tech Talk 10/20/1999). "Once you have the sequence of building blocks for a given polysaccharide, you can start cracking its function in the body," said Professor Sasisekharan.

Similar sequencing techniques for DNA and proteins have been instrumental in shaping the biotechnology industry and have led to applications making those compounds household names. With the new tool, "we hope to articulate that these sugars are also fundamental to biology--that theyre a new and important frontier," said Ganesh Venkataraman, a research associate in the Harvard-MIT Division of Health Sciences and Techn
'"/>

Contact: Elizabeth Thomson, MIT News Office
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
11-Sep-2000


Page: 1 2 3

Related biology news :

1. Conservation International & SC Johnson invest in Ecuadors rainforest to offset climate impacts
2. Exxon Valdez oil spill impacts lasting far longer than expected, scientists say
3. Lewis and Clark notes reveal history of human impacts
4. Media advisory - wildland fire impacts on watersheds
5. All species are not created equal when assessing the impacts of species loss on ecosystems
6. CAST releases report on environmental impacts of grazing systems on our nations resources
7. Cosmic impacts implicated in both the rise and fall of dinosaurs
8. Marylands proposed crab regulations could have large economic impacts
9. Virginia Tech leads global effort to sort out social, economic impacts of agricultural biotechnology
10. "Soft" science? Fats health impacts are often oversimplified, Science news feature contends
11. Smog impacts: Hurtling through airways, tiny particles may do more damage than previously assumed

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: MIT tool impacts multi billion dollar drug

(Date:2/5/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/6lngtl/global_biometrics ) ... Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, ... their offering. , In global ... anticipated to overtake North America ... towards IT security, government biometric based projects such ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... "Biometrics - A Global Market Overview" report to their ... technology is to ensure that an individual is who she/he ... may make use of a person,s unique physical characteristics, such ...
(Date:1/22/2015)... MELBOURNE, Fla. , Jan. 13, 2015  Today, ... wearable technology, launched its crowdfunding campaign on Fundable, ... accelerate the build of production capacity to meet ... Photo - http://photos.prnewswire.com/prnh/20150113/168790 ...
Breaking Biology News(10 mins):Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 2Global Biometrics Market (2014-2020): Market Forecast By Technologies, Applications, End Use, Regions and Countries 3Biometrics - A Global Market Overview 2Biometrics - A Global Market Overview 3FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2
(Date:3/5/2015)... Texas (PRWEB) March 05, 2015 ... of acute and chronic orthopedic conditions such as ... knee, tennis elbow, and joint pain due to ... be administered during orthopedic surgeries to promote better ... scientific advances in nearly pain-free bone marrow harvesting ...
(Date:3/4/2015)... 2015 The UPMC Center for Health Security ... the Emerging Leaders in Biosecurity Initiative (ELBI). As part ... field of biosecurity, UPMC has selected 28 US and ... of backgrounds, including biological science, medicine, policy, the military, ... "With the vision and support of the Defense Threat ...
(Date:3/4/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/nqxxt3/biomarkers ) ... report "Biomarkers - Technologies, Markets and Companies" ... report follows the broad definition of a biomarker ... and evaluated as an indicator of normal biological ... to a therapeutic intervention. Tests based on biomarkers ...
(Date:3/4/2015)... (PRWEB) March 04, 2015 PRC ... in the San Francisco Bay Area, will exhibit and ... Israel Conference 2015 on March 25th and 26th ... to build relationships with Israeli life science companies seeking ... trials. The company’s services span all phases of human ...
Breaking Biology Technology:Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 2Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 3Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 4Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 5UPMC Center for Health Security Announces 2015 Emerging Leaders in Biosecurity 2UPMC Center for Health Security Announces 2015 Emerging Leaders in Biosecurity 3Global Biomarkers Report 2014-2024 - Technologies, Markets and Companies 2Global Biomarkers Report 2014-2024 - Technologies, Markets and Companies 3PRC Clinical to Present at Inaugural Outsourcing in Clinical Trials Israel Conference 2015 on March 25 and 26th in Tel Aviv 2PRC Clinical to Present at Inaugural Outsourcing in Clinical Trials Israel Conference 2015 on March 25 and 26th in Tel Aviv 3PRC Clinical to Present at Inaugural Outsourcing in Clinical Trials Israel Conference 2015 on March 25 and 26th in Tel Aviv 4
Cached News: