HOME >> BIOLOGY >> NEWS
MIT tool impacts multi-billion dollar drug

CAMBRIDGE, Mass.-- MIT scientists and colleagues announce work that could impact the multi-billion dollar heparin industry and change how the FDA regulates that common anti-clotting drug. The work is the first application of a novel analytical tool announced by the same core group of researchers last fall. Other important applications promise to follow.

"Periods of great discovery in science are almost always preceded by the development of new tools," writes Professor Matthew A. Nugent of Boston University in the September 12 issue of the Proceedings of the National Academy of Sciences. His commentary accompanies two articles by the MIT researchers describing the heparin work.

MYSTERIOUS WORLD
The new analytical tool probes the mysterious world of complex sugars. Although these compounds have recently been shown to play important roles in processes from viral infection to tissue development, "the field has lagged far behind the mainstream work on proteins and DNA," said Ram Sasisekharan, an associate professor in the Division of Bioengineering and Environmental Health (BEH) and leader of the MIT team.

Thats because the complex sugars have many more building blocks than their better-known cousins, DNA and proteins, making them more difficult to study. The MIT tool is a quick, easy way to determine the structure, or order of building blocks, in these sugars (MIT Tech Talk 10/20/1999). "Once you have the sequence of building blocks for a given polysaccharide, you can start cracking its function in the body," said Professor Sasisekharan.

Similar sequencing techniques for DNA and proteins have been instrumental in shaping the biotechnology industry and have led to applications making those compounds household names. With the new tool, "we hope to articulate that these sugars are also fundamental to biology--that theyre a new and important frontier," said Ganesh Venkataraman, a research associate in the Harvard-MIT Division of Health Sciences and Techn
'"/>

Contact: Elizabeth Thomson, MIT News Office
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
11-Sep-2000


Page: 1 2 3

Related biology news :

1. Conservation International & SC Johnson invest in Ecuadors rainforest to offset climate impacts
2. Exxon Valdez oil spill impacts lasting far longer than expected, scientists say
3. Lewis and Clark notes reveal history of human impacts
4. Media advisory - wildland fire impacts on watersheds
5. All species are not created equal when assessing the impacts of species loss on ecosystems
6. CAST releases report on environmental impacts of grazing systems on our nations resources
7. Cosmic impacts implicated in both the rise and fall of dinosaurs
8. Marylands proposed crab regulations could have large economic impacts
9. Virginia Tech leads global effort to sort out social, economic impacts of agricultural biotechnology
10. "Soft" science? Fats health impacts are often oversimplified, Science news feature contends
11. Smog impacts: Hurtling through airways, tiny particles may do more damage than previously assumed

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2017)... the health IT company that operates the largest health ... today announced a Series B investment from BlueCross BlueShield ... investment and acquisition accelerates higi,s strategy to create the ... activities through the collection and workflow integration of ambient ... secures data today on behalf of over 36 million ...
(Date:3/27/2017)... , March 27, 2017  Catholic Health Services ... Management Systems Society (HIMSS) Analytics for achieving Stage ... Model sm . In addition, CHS previously earned ... hospitals using an electronic medical record (EMR). ... high level of EMR usage in an outpatient ...
(Date:3/24/2017)... , Mar 24, 2017 Research and Markets ... System Market Analysis & Trends - Industry Forecast to 2025" ... ... grow at a CAGR of around 15.1% over the next decade ... industry report analyzes the market estimates and forecasts for all the ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 23, 2017 , ... Vortex Biosciences , ... “Label-free isolation of prostate circulating tumor cells using Vortex microfluidic technology ” in Nature ... a collaboration with Dr. Dino Di Carlo and Dr. Matthew Rettig at the University ...
(Date:5/23/2017)... , ... May 23, 2017 , ... Bacterial biofilms, surface ... molecules, can cause diverse pathologies ranging from food poisoning and catheter infections to gum ... is in the tens of billions of dollars per year, there is currently a ...
(Date:5/22/2017)... ... May 22, 2017 , ... Stratevi, a boutique firm that partners ... Coast. It has opened an office in downtown Boston at 745 Atlantic Ave. ... more important to generate evidence on the value they provide, not just to patients, ...
(Date:5/21/2017)... ... May 19, 2017 , ... Ovation Fertility scientists’ work is ... of Bioanalysts (AAB) and the College of Reproductive Biology (CRB) today and Saturday ... to excellence in clinical laboratory services and regulations. , “We are pleased ...
Breaking Biology Technology:
Cached News: