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MRI Scans Following Heart Attack Could Determine Future Health

Magnetic resonance imaging (MRI) of the heart after a heart attack may help determine which patients do well and which ones will later suffer complications such as recurrent heart attack, congestive heart failure, stroke or death, according to a study led by Johns Hopkins researchers.

"This technology could be a cost-effective means to identify which patients need to be monitored in order to prevent or minimize future cardiac events," says Jo o A.C. Lima, M.D., senior author of the study and an associate professor of medicine at Hopkins.

Patients whose MRI scans showed their hearts' capillaries were partially blocked with dying blood cells and debris following a heart attack were more likely to suffer frequent heart complications within the next two years. Capillaries are the body's narrowest blood vessels and are more easily clogged by such debris than larger vessels -- arteries and veins.

In addition, researchers noted that the more serious the heart attack, the higher the patient's risk of later problems.

"Vascular obstruction shown on the MRI scans accurately predicted long-term outcome in patients who had heart attacks," Lima says. "MRI also helped determine the size of the heart attack and the subsequent risk of developing complications."

Results of the study were published in the March 3 issue of Circulation: Journal of the American Heart Association.

Researchers did MRI scans of 44 patients' hearts an average of 10 days after heart attack. Seventeen of the patients returned six months later for a repeat MRI scan.

Of the 11 patients who had vascular obstruction, five (45 percent) experienced at least one significant post-heart attack complication, such as a second heart attack, congestive heart failure, a stroke or death. In contrast, only three (9 percent) of the 33 without obstruction suffered later complications. Problems occurred an average of 14 months afte
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Contact: Karen Infeld
kinfeld@welchlink.welch.jhu.edu
(410)955-1534
Johns Hopkins Medical Institutions
3-Mar-1998


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