he time required to produce and set protein crystals up in the beamline, illuminate them with x-rays, and collect the data. Automation of the entire process, including the use of a unique crystal-growing robotic system designed and built by a team of engineers and technicians led by Joe Jaklevic with Berkeley Lab's Engineering Division, will be a key.

The project will also benefit from automation tools being developed and built to increase the throughput and efficiency of the structural determination process, including robotic crystal mounting and alignment and expert computation systems.

Data collected by Kim and his collaborators, along with that collected by the other NIGMS grant recipients is to form the foundation of a public resource linking sequence, structural, and functional information. NIGMS will make this information be available on the Internet to all scientists.

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Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
26-Sep-2000

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