HOME >> BIOLOGY >> NEWS
Making a safer anthrax vaccine using spinach

BALTIMORE March 10, 2003 Researchers at Thomas Jefferson University have developed a strategy for making a safer anthrax vaccine; enlisting the help of spinach plants to manufacture a key component. They report their findings today at the American Society for Microbiology's Biodefense Research Meeting.

"Protective antigen (PA) of Bacillus anthracis is one of the three components of the anthrax toxin," says Alexander Karasev, a lead researcher on the study. "Purified PA is currently used as a vaccine against anthrax. However, the licensed vaccine derived from apathogenic B. anthracis has side effects and a more efficacious and safer vaccine is needed."

Karasev and his colleagues have genetically engineered a tobacco mosaic virus that, when inserted into spinach plants, instructs the plants to manufacture fragments of PA. The fragments can then easily be purified and used in a vaccine. They are already being used in the production of PA specific antibodies in laboratory animals.

"Plants can be an excellent vehicle for production of a subunit vaccine against anthrax based on protective antigen," says Karasev.


'"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
10-Mar-2003


Page: 1

Related biology news :

1. Making a friendlier mosquito
2. Making sense of the brains mind-boggling complexity
3. Making protein nanostructures
4. Making the most of stem cells
5. Making of mouse marks move toward mitochondrial medicine
6. Making new muscle: Researchers in Rome produce a mouse that can regenerate its tissues
7. Making sense of bacterial biodiversity
8. Making sense of the genome
9. A new twist on an age-old problem: Making knee replacements last
10. Making sense of Marfan syndrome
11. Making the most of lymphopenia

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/2/2017)... March 2, 2017 Summary This ... understand Merck KGaA and its partnering interests and activities ... Description The Partnering Deals and Alliance since ... activity of one of the world,s leading life sciences ... upon purchase to ensure inclusion of the most up ...
(Date:2/28/2017)...   Acuant , a leading provider of data ... to new and core technologies building upon the acquisition ... and desktop Acuant FRM TM facial recognition and ... time manual review of identity documents by accredited professionals. ... and most accurate capture software to streamline workflows by ...
(Date:2/26/2017)... DALLAS , Feb. 25, 2017  Securus ... justice technology solutions for public safety, investigation, corrections ... of Recidivism and Reentry. "Too often, ... State prisons and county jails are trying to ... of inmates and friends and family members. While significant ...
Breaking Biology News(10 mins):
(Date:3/24/2017)... 2017 Research and Markets has announced the ... Global Strategic Business Report" report to their offering. ... This report analyzes the ... Million. Annual estimates and forecasts are provided for the period 2014 ... secondary research. The report profiles 25 companies including ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... viscoelastic material that exhibits both viscous and elastic characteristics when deformed, which is ... polymer exhibits properties to gently absorb compressive forces and return to its natural ...
(Date:3/23/2017)... , March 23, 2017  GlobeImmune, Inc. today announced ... the sale of 12,835,490 shares of its common stock ... of companies. In connection with the sale of its common ... cash and issue to GlobeImmune 200,000 shares, an estimated ... "We are pleased to enter into this ...
(Date:3/23/2017)... According to a report by Transparency Market Research (TMR), ... the presence of a large pool of participants; however, only a ... Sigma-Aldrich, compete with each other in this market. With Proliant being ... of this market in 2016.  ... As of now, a large number of vendors are ...
Breaking Biology Technology:
Cached News: