HOME >> BIOLOGY >> NEWS
Making a safer anthrax vaccine using spinach

BALTIMORE March 10, 2003 Researchers at Thomas Jefferson University have developed a strategy for making a safer anthrax vaccine; enlisting the help of spinach plants to manufacture a key component. They report their findings today at the American Society for Microbiology's Biodefense Research Meeting.

"Protective antigen (PA) of Bacillus anthracis is one of the three components of the anthrax toxin," says Alexander Karasev, a lead researcher on the study. "Purified PA is currently used as a vaccine against anthrax. However, the licensed vaccine derived from apathogenic B. anthracis has side effects and a more efficacious and safer vaccine is needed."

Karasev and his colleagues have genetically engineered a tobacco mosaic virus that, when inserted into spinach plants, instructs the plants to manufacture fragments of PA. The fragments can then easily be purified and used in a vaccine. They are already being used in the production of PA specific antibodies in laboratory animals.

"Plants can be an excellent vehicle for production of a subunit vaccine against anthrax based on protective antigen," says Karasev.


'"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
10-Mar-2003


Page: 1

Related biology news :

1. Making a friendlier mosquito
2. Making sense of the brains mind-boggling complexity
3. Making protein nanostructures
4. Making the most of stem cells
5. Making of mouse marks move toward mitochondrial medicine
6. Making new muscle: Researchers in Rome produce a mouse that can regenerate its tissues
7. Making sense of bacterial biodiversity
8. Making sense of the genome
9. A new twist on an age-old problem: Making knee replacements last
10. Making sense of Marfan syndrome
11. Making the most of lymphopenia

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)... , May 16, 2017   Bridge Patient ... organizations, and MD EMR Systems , an ... partner for GE, have established a partnership to ... product and the GE Centricity™ products, including Centricity ... These new integrations will allow ...
(Date:4/18/2017)... 2017  Socionext Inc., a global expert in SoC-based imaging and ... the M820, which features the company,s hybrid codec technology. A demonstration ... Probe, Inc., will be showcased during the upcoming Medtec Japan at ... the Las Vegas Convention Center April 24-27. ... Click here for an ...
(Date:4/11/2017)... 11, 2017 Crossmatch®, a globally-recognized leader ... today announced that it has been awarded a ... Activity (IARPA) to develop next-generation Presentation Attack Detection ... "Innovation has been a driving force within Crossmatch ... allow us to innovate and develop new technologies ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia Inc ., a ... Webinar titled, “Pathology is going digital. Is your lab ready?” with Dr. Nicolas ... practices and how Proscia improves lab economics and realizes an increase in diagnostic ...
(Date:10/11/2017)... Florida (PRWEB) , ... October 11, 2017 , ... ... Drug Administration (FDA) has granted orphan drug designation to SBT-100, its novel anti-STAT3 ... for the treatment of osteosarcoma. SBT-100 is able to cross the cell membrane ...
(Date:10/10/2017)... Oct. 10, 2017 International research firm Parks Associates ... speak at the TMA 2017 Annual Meeting , October 11 in ... the residential home security market and how smart safety and security products ... Parks Associates: Smart ... "The residential security market ...
(Date:10/9/2017)... ... ... The award-winning American Farmer television series will feature 3 Bar Biologics in ... 8:30aET on RFD-TV. , With global population estimates nearing ten billion people by ... feed a growing nation. At the same time, many of our valuable resources are ...
Breaking Biology Technology:
Cached News: