HOME >> BIOLOGY >> NEWS
Making the most of lymphopenia

A study undertaken by investigators at The Scripps Research Institute (TSRI) suggests a new, potentially more effective way to battle cancerhit the immune system with cancer vaccines or cancer cells when it's down and it will bounce back swinging harder than ever against those cancer cells.

The technique involves administering an injection of fresh immune cells to replace the ones that die immediately after chemotherapy or irradiation. An injection of cancer cells at the same time serves as a form of "immunotherapy," which induces a person's immune system to attack existing colonies of those cancer cells. In the technique, the fresh immune cells immediately begin to multiply and, because they see the cancer cells, they are rapidly activated to kill them.

"The treatment has utility on the basis of its simplicity," says TSRI immunology Professor Argyrios N. Theofilopoulos, M.D., who led the study.

Theofilopoulos's study, which is published in the latest issue of the Journal of Clinical Investigation, suggests that immunotherapy should be initiated immediately after chemotherapy or irradiation because the reduction in the body's T cells is actually an advantage.

"If you have only a small number of T cells," says Theofilopoulos, "It is very likely that, during their subsequent expansion, you will develop a strong T cell response [to the cancer]."

For years, the main treatment for various sorts of cancers has been systemic chemotherapeuticsdrugs that have a cytotoxic effect on rapidly dividing cancer cellsor irradiation, the use of x-rays or some other sort of ionizing radiation that is also lethal to cancer cells. However, they both cause collateral damage, killing non-cancerous cells as well. Like innocent bystanders, T cells and other cells of the immune system are killed along with the tumor cells during chemotherapy and irradiationa state referred to as "lymphopenia."

Immunotherapy is another approach to cancer therap
'"/>

Contact: Robin B. Clark
rclark@scripps.edu
858-784-8134
Scripps Research Institute
10-Jul-2002


Page: 1 2 3

Related biology news :

1. Making a friendlier mosquito
2. Making sense of the brains mind-boggling complexity
3. Making protein nanostructures
4. Making the most of stem cells
5. Making of mouse marks move toward mitochondrial medicine
6. Making new muscle: Researchers in Rome produce a mouse that can regenerate its tissues
7. Making sense of bacterial biodiversity
8. Making sense of the genome
9. Making a safer anthrax vaccine using spinach
10. A new twist on an age-old problem: Making knee replacements last
11. Making sense of Marfan syndrome

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/1/2020)... (PRWEB) , ... May 01, 2020 , ... More than ... Comprehensive Cancer Center’s High-Risk Cancer Program, which is led by two genetic counselors. , ... solutions, today announced it is teaming up with UConn’s High Rick Program to ensure ...
(Date:4/26/2020)... ... April 23, 2020 , ... SECO , ... FII Tech Growth managed by Fondo Italiano d’Investimento SGR, today announced a partnership ... development of Respira, a new non-invasive pulmonary ventilator created in response to the ...
(Date:4/22/2020)... ... April 21, 2020 , ... USDM Life Sciences ... compliance, announces a new managed service to improve quality management for regulated companies, ... and USDM Life Sciences (USDM) – Unify Compliance Cloud is a suite of ...
Breaking Biology News(10 mins):
(Date:5/21/2020)... ... May 19, 2020 , ... Eaton Square is pleased to announce its ... Company, a biotechnology and medical technology-focused strategy and M&A advisory firm. , This is ... States, linking US and Asia Pacific healthcare innovators with capital and investors. , Popper ...
(Date:5/15/2020)... (PRWEB) , ... May 14, 2020 , ... This new ... unforeseen and the most pressing questions answered quickly as the need arises. Lachman’s OnCall ... offering valuable advice at affordable rates. , Lachman OnCall™ SMEs are available normal ...
(Date:5/14/2020)... ... 13, 2020 , ... In collaboration with Sartorius, Biocompare has ... Life Science Lab . The comprehensive information source was created for life scientists ... handling to contamination control. , The content hub features the latest guidance about ...
(Date:5/5/2020)... ... ... ProductLife Group has marked the next phase in its global ... years at Altran, where he was Group VP of Life Sciences and Head of ... Xavier was involved in his early career in the development of new medical devices ...
Breaking Biology Technology:
Cached News: