HOME >> BIOLOGY >> NEWS
Mapping genes for schizophrenia in the South Pacific

ARTICLE: "Genome-wide multipoint linkage analyses of multiplex schizophrenia pedigrees from the oceanic nation of Palau"

AUTHORS: B. Devlin, Silviu-Alin Bacanu, Kathryn Roeder, Fred Reimherr, Paul Wender, Brandi Galke, Denise Novasad, Allan Chu, Karen T.Cuenco, Seba Tiobek, Caleb Otto, William Byerley

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA; Department of Statistics, Carnegie Mellon University, Pittsburgh, PA; Department of Psychiatry, University of Utah Medical Center, Salt Lake City, Utah; Department of Psychiatry, University of California, Irvine, CA; Department of Genetics, University of Pittsburgh, Pittsburgh, PA; Belau National Hospital, Korror, Palau.

Schizophrenia is a devastating neuropsychiatric disorder that afflicts 1% of the worldwide population. Remarkably, the prevalence of schizophrenia is the same throughout the world despite differing cultures and environments of most nations. It is also notable that the cardinal signs and symptoms of schizophrenia - hallucinations and delusions - are the same throughout the world. In addition, family, twin and adoption studies from different populations indicate genetic factors contribute substantially to susceptibility to this illness. Small, isolated populations can be useful for gene mapping for two reasons: the genetic causes of illness are typically less heterogeneous, and isolated populations often contain large extended multiplex pedigrees ideal for mapping genes. For these reasons, the investigators initiated a genetic study of schizophrenia in Palau, Micronesia. Palau, also termed Belau, which is located approximately 725 miles southwest of Guam in the South Pacific. Presentation and symptoms of schizophrenia are no different in Palau.

The study findings, published in the September issue of Molecular Psychiatry, indicate that the genetic factors are distinct for each of the 5 families. The findings were perhaps somewhat unexpecte
'"/>

Contact: Frank Sissingh
molecularpsychiatry@mednet.ucla.edu
310-206-6739
Molecular Psychiatry
3-Sep-2002


Page: 1 2

Related biology news :

1. Mapping the evolution of a virus
2. Organization for Human Brain Mapping 2004 Annual Meeting
3. Mapping a road to understanding human health
4. Organization for Human Brain Mapping annual meeting abstract highlights
5. Organization for Human Brain Mapping 2003 Annual Meeting
6. Mapping proteins
7. Elementary Students Mapping Virginia Wildlife
8. Rare Brain Mapping Procedure Provides Unique Picture Of Two Areas Concerned With Language Processing and Production
9. Subterranean Mapping Method Will Find Homes For Pollution-Eating Bacteria
10. Mapping The Way To A Bigger Prawn
11. Brain Mapping In Real Time

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/6/2017)... Forecasts by Product Type (EAC), ... End-Use (Transportation & Logistics, Government & Public Sector, Utilities ... Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), ... you looking for a definitive report on the $27.9bn ... ...
(Date:4/3/2017)... April 3, 2017  Data captured by ... platform, detected a statistically significant association between ... to treatment and objective response of cancer ... to predict whether cancer patients will respond ... as well as to improve both pre-infusion potency ...
(Date:3/28/2017)... PUNE, India , March 28, 2017 ... (Analog, IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), ... Maintenance), Vertical, and Region - Global Forecast to 2022", ... 30.37 Billion in 2016 and is projected to reach ... 15.4% between 2017 and 2022. The base year considered ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Bay, Florida (PRWEB) , ... October 11, 2017 ... ... and Drug Administration (FDA) has granted orphan drug designation to SBT-100, its novel ... (sdAb) for the treatment of osteosarcoma. SBT-100 is able to cross the cell ...
(Date:10/10/2017)... (PRWEB) , ... October 10, ... ... development-stage cancer-focused pharmaceutical company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed ... targeted HPLN (Hybrid Polymerized Liposomal Nanoparticle), a technology developed in collaboration with ...
(Date:10/10/2017)... , ... October 10, 2017 , ... Dr. Bob Harman, ... his local San Diego Rotary Club. The event entitled “Stem Cells ... and had 300+ attendees. Dr. Harman, DVM, MPVM was joined by two human ...
(Date:10/10/2017)... Oct. 10, 2017 SomaGenics announced the receipt ... to develop RealSeq®-SC (Single Cell), expected to be the ... RNAs (including microRNAs) from single cells using NGS methods. ... need to accelerate development of approaches to analyze the ... "New techniques for measuring levels of mRNAs in ...
Breaking Biology Technology:
Cached News: