HOME >> BIOLOGY >> NEWS
Mapping genes for schizophrenia in the South Pacific

ARTICLE: "Genome-wide multipoint linkage analyses of multiplex schizophrenia pedigrees from the oceanic nation of Palau"

AUTHORS: B. Devlin, Silviu-Alin Bacanu, Kathryn Roeder, Fred Reimherr, Paul Wender, Brandi Galke, Denise Novasad, Allan Chu, Karen T.Cuenco, Seba Tiobek, Caleb Otto, William Byerley

Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA; Department of Statistics, Carnegie Mellon University, Pittsburgh, PA; Department of Psychiatry, University of Utah Medical Center, Salt Lake City, Utah; Department of Psychiatry, University of California, Irvine, CA; Department of Genetics, University of Pittsburgh, Pittsburgh, PA; Belau National Hospital, Korror, Palau.

Schizophrenia is a devastating neuropsychiatric disorder that afflicts 1% of the worldwide population. Remarkably, the prevalence of schizophrenia is the same throughout the world despite differing cultures and environments of most nations. It is also notable that the cardinal signs and symptoms of schizophrenia - hallucinations and delusions - are the same throughout the world. In addition, family, twin and adoption studies from different populations indicate genetic factors contribute substantially to susceptibility to this illness. Small, isolated populations can be useful for gene mapping for two reasons: the genetic causes of illness are typically less heterogeneous, and isolated populations often contain large extended multiplex pedigrees ideal for mapping genes. For these reasons, the investigators initiated a genetic study of schizophrenia in Palau, Micronesia. Palau, also termed Belau, which is located approximately 725 miles southwest of Guam in the South Pacific. Presentation and symptoms of schizophrenia are no different in Palau.

The study findings, published in the September issue of Molecular Psychiatry, indicate that the genetic factors are distinct for each of the 5 families. The findings were perhaps somewhat unexpecte
'"/>

Contact: Frank Sissingh
molecularpsychiatry@mednet.ucla.edu
310-206-6739
Molecular Psychiatry
3-Sep-2002


Page: 1 2

Related biology news :

1. Mapping the evolution of a virus
2. Organization for Human Brain Mapping 2004 Annual Meeting
3. Mapping a road to understanding human health
4. Organization for Human Brain Mapping annual meeting abstract highlights
5. Organization for Human Brain Mapping 2003 Annual Meeting
6. Mapping proteins
7. Elementary Students Mapping Virginia Wildlife
8. Rare Brain Mapping Procedure Provides Unique Picture Of Two Areas Concerned With Language Processing and Production
9. Subterranean Mapping Method Will Find Homes For Pollution-Eating Bacteria
10. Mapping The Way To A Bigger Prawn
11. Brain Mapping In Real Time

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mapping genes for schizophrenia the South Pacific

(Date:10/15/2014)... have linked increased resistance to bacterial pneumonia in female ... hormone estrogen. , Females are naturally more resistant to ... scientists has shown that increased resistance to bacterial pneumonia ... oxide synthase 3 (NOS3). They also show that this ... female sex hormone estrogen. , The team, lead by ...
(Date:10/14/2014)... shows SIRT6—a protein known to inhibit the growth ... skin cancers by turning on an enzyme that increases ... Previously considered protective, SIRT6 is part of a family ... stability and prevent some of the genetic flaws associated ... lead to cancer. This study, in the journal,s October ...
(Date:10/14/2014)... oil supplements, rich in omega-3 fatty acids, do not reduce ... the heart can beat as fast as 150 beats a ... Montreal Heart Institute were published in the Journal of ... For the trial, 337 patients with atrial fibrillation not receiving ... fish oil a day or to placebo for up to ...
Breaking Biology News(10 mins):Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2
(Date:10/20/2014)... Inc. (TSXV: BRM) ("Biorem" or "the Company") today announced four new ... and provides a good start to Q4.  The orders are for ... and one in the Middle East . ... Peter Bruijns , President & CEO. "Total bidding activity and ... have been for any complete year since the company has tracked ...
(Date:10/20/2014)... 20, 2014 OncLive® ... Cancer Center at Thomas Jefferson University has joined ... the Strategic Alliance Partnership program, the Sidney Kimmel ... to raise awareness of the Center’s cutting-edge research ... projects. Clinicians and other health care professionals from ...
(Date:10/19/2014)... OCTOBER 20-22, 2014: The 9th Annual ... take place at the Congress Center Basel, ... now available at http://www.abim.ch . ... from all over the globe will exchange ... products and developments on the world market. ...
(Date:10/19/2014)... Asia-Pacific Speech Analytics market report defines and segments the ... of revenue. This market is estimated to grow from ... at a Compound Annual Growth Rate (CAGR) of 23.9% ... of the Asia-Pacific Speech Analytics market report to get ... provides a glimpse of the segmentation in the market, ...
Breaking Biology Technology:Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4
Cached News: