HOME >> BIOLOGY >> NEWS
Mapping the evolution of a virus

A University of California scientist working at Los Alamos National Laboratory with collaborators from the University of Cambridge (England) and the World Health Organization National Influenza Center at Erasmus Medical Center, (Rotterdam, Netherlands) have developed a computer modeling method for mapping the evolution of the influenza virus. The method could soon help medical researchers worldwide develop a better understanding of certain mutations in influenza and other viruses that allow diseases to dodge the human immune system.

In a paper published in today's edition of the journal Science, the team of scientists from the United States and Europe describe their work quantifying and visualizing the antigenic and genetic evolution of the influenza A (H3N2) virus from its initial introduction into humans in 1968 up to 2003. The study resulted in a map that shows the virus evolved as a series of 11 closely related virus clusters as it has sought to elude human immunity over the decades.

The mapping method will allow researchers involved in vaccine development and viral surveillance programs for influenza, and potentially for other pathogens such as Hepatitis C and HIV as well, to quantify and visualize the evolution of these viruses. It can assist in monitoring antigenic differences among vaccine and circulating viral strains, and can help in quantifying the effects of vaccination. The approach also offers a route for predicting the relative infection success of emerging virus strains.

According to Los Alamos computational biologist Alan Lapedes, "This collaboration was particularly exciting because it involved close interaction between experts in computation and virology and medicine. Once we had created the map, we tested its reliability by making hundreds of predictions of how well certain strains might match up and then conducting laboratory tests to check the predictions. It's very gratifying that this basic research also
'"/>

Contact: Todd Hanson
tahanson@lanl.gov
505-665-2085
DOE/Los Alamos National Laboratory
20-Jul-2004


Page: 1 2

Related biology news :

1. Organization for Human Brain Mapping 2004 Annual Meeting
2. Mapping a road to understanding human health
3. Organization for Human Brain Mapping annual meeting abstract highlights
4. Organization for Human Brain Mapping 2003 Annual Meeting
5. Mapping proteins
6. Mapping genes for schizophrenia in the South Pacific
7. Elementary Students Mapping Virginia Wildlife
8. Rare Brain Mapping Procedure Provides Unique Picture Of Two Areas Concerned With Language Processing and Production
9. Subterranean Mapping Method Will Find Homes For Pollution-Eating Bacteria
10. Mapping The Way To A Bigger Prawn
11. Brain Mapping In Real Time

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/25/2019)... ... April 23, 2019 , ... Leak Detection Associates, the ... Biotechnology, Medical Device and Food Packaging Industries’ is pleased to announce the completion ... Jersey. The new facility was custom designed to meet enhanced manufacturing capabilities that ...
(Date:4/25/2019)... ... April 23, 2019 , ... In ... in the scientific literature. However, in many cases the magnitude of these deficits ... a particularly challenging population, given neurocognitive effects may impact developmental trajectories, and patients ...
(Date:4/25/2019)... (PRWEB) , ... April 24, 2019 , ... ... Human Services Secretary Alex Azar today, a broad collective of 62 individual scientists, ... the American Society of Gene & Cell Therapy (ASGCT), across industry and academia ...
Breaking Biology News(10 mins):
(Date:5/14/2019)... ... May 14, 2019 , ... Gateway Genomics , a leading ... space from 2,500 to 5,000 square feet. , “This past year has seen ... says Gateway Genomics CEO, Chris Jacob. “The SneakPeek At-Home test, which is mailed directly ...
(Date:5/7/2019)... ... May 06, 2019 , ... "The new Liquid ... of repositories being asked to store cellular products being used in adoptive ... who are world leaders, who have shared their expertise in building and managing ...
(Date:5/4/2019)... ... May 03, 2019 , ... ... of the Diopsys® ffERG/Photopic Negative Response vision test, a new full ... 2050, it is estimated that 6.3 million Americans will have glaucoma, with black ...
(Date:5/2/2019)... S.D. (PRWEB) , ... April 30, 2019 , ... The ... from industrial scale macro breweries to local craft breweries, and even home brewing clubs ... very complex chemical and biological processes, that when mastered can produce a superb product. ...
Breaking Biology Technology:
Cached News: