HOME >> BIOLOGY >> NEWS
Mapping the evolution of a virus

A University of California scientist working at Los Alamos National Laboratory with collaborators from the University of Cambridge (England) and the World Health Organization National Influenza Center at Erasmus Medical Center, (Rotterdam, Netherlands) have developed a computer modeling method for mapping the evolution of the influenza virus. The method could soon help medical researchers worldwide develop a better understanding of certain mutations in influenza and other viruses that allow diseases to dodge the human immune system.

In a paper published in today's edition of the journal Science, the team of scientists from the United States and Europe describe their work quantifying and visualizing the antigenic and genetic evolution of the influenza A (H3N2) virus from its initial introduction into humans in 1968 up to 2003. The study resulted in a map that shows the virus evolved as a series of 11 closely related virus clusters as it has sought to elude human immunity over the decades.

The mapping method will allow researchers involved in vaccine development and viral surveillance programs for influenza, and potentially for other pathogens such as Hepatitis C and HIV as well, to quantify and visualize the evolution of these viruses. It can assist in monitoring antigenic differences among vaccine and circulating viral strains, and can help in quantifying the effects of vaccination. The approach also offers a route for predicting the relative infection success of emerging virus strains.

According to Los Alamos computational biologist Alan Lapedes, "This collaboration was particularly exciting because it involved close interaction between experts in computation and virology and medicine. Once we had created the map, we tested its reliability by making hundreds of predictions of how well certain strains might match up and then conducting laboratory tests to check the predictions. It's very gratifying that this basic research also
'"/>

Contact: Todd Hanson
tahanson@lanl.gov
505-665-2085
DOE/Los Alamos National Laboratory
20-Jul-2004


Page: 1 2

Related biology news :

1. Organization for Human Brain Mapping 2004 Annual Meeting
2. Mapping a road to understanding human health
3. Organization for Human Brain Mapping annual meeting abstract highlights
4. Organization for Human Brain Mapping 2003 Annual Meeting
5. Mapping proteins
6. Mapping genes for schizophrenia in the South Pacific
7. Elementary Students Mapping Virginia Wildlife
8. Rare Brain Mapping Procedure Provides Unique Picture Of Two Areas Concerned With Language Processing and Production
9. Subterranean Mapping Method Will Find Homes For Pollution-Eating Bacteria
10. Mapping The Way To A Bigger Prawn
11. Brain Mapping In Real Time

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2019)... ... June 14, 2019 , ... ... customer, will deliver a joint presentation with Versiti’s CIO at the Healthcare ... the Rosen Shingle Creek Resort. , Versiti Vice President and Chief Information Officer, ...
(Date:6/11/2019)... ... June 10, 2019 , ... Improved Pharma LLC announces ... 2019 issue of AAPS PharmSciTech. The article was published online on April 29th, 2019. ... Pharma, along with Xiaoming Sean Chen of Purdue University. , The article is the ...
(Date:6/4/2019)... ... June 04, 2019 , ... ... appointment of Susan Murphy as the new President of Molecular Devices, replacing Greg ... Devices’ parent company, Danaher Corporation. , Since joining Molecular Devices in a scientific ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... ... May 30, 2019 , ... ... on Data Integrity on July 08-09, 2019 in Boston, MA. This peer recommended ... medical device organizations. , The training will kick off with a compendial treatment ...
(Date:5/15/2019)... , ... May 15, 2019 , ... Milton Hershey School® ... recognition for his work within the biomedical industry, where he is changing lives by ... devices. , “William Harding epitomizes the vision of our founders – Milton and ...
(Date:5/7/2019)... ... May 06, 2019 , ... "The new ... number of repositories being asked to store cellular products being used in ... contributors who are world leaders, who have shared their expertise in building and ...
(Date:5/2/2019)... ... May 02, 2019 , ... Stay on top of ... device and food industries. Access to all webinars is free, so be sure to ... your field! , Visit http://www.xtalks.com to see our upcoming webinars: , CLINICAL ...
Breaking Biology Technology:
Cached News: