HOME >> BIOLOGY >> NEWS
Mapping the evolution of a virus

A University of California scientist working at Los Alamos National Laboratory with collaborators from the University of Cambridge (England) and the World Health Organization National Influenza Center at Erasmus Medical Center, (Rotterdam, Netherlands) have developed a computer modeling method for mapping the evolution of the influenza virus. The method could soon help medical researchers worldwide develop a better understanding of certain mutations in influenza and other viruses that allow diseases to dodge the human immune system.

In a paper published in today's edition of the journal Science, the team of scientists from the United States and Europe describe their work quantifying and visualizing the antigenic and genetic evolution of the influenza A (H3N2) virus from its initial introduction into humans in 1968 up to 2003. The study resulted in a map that shows the virus evolved as a series of 11 closely related virus clusters as it has sought to elude human immunity over the decades.

The mapping method will allow researchers involved in vaccine development and viral surveillance programs for influenza, and potentially for other pathogens such as Hepatitis C and HIV as well, to quantify and visualize the evolution of these viruses. It can assist in monitoring antigenic differences among vaccine and circulating viral strains, and can help in quantifying the effects of vaccination. The approach also offers a route for predicting the relative infection success of emerging virus strains.

According to Los Alamos computational biologist Alan Lapedes, "This collaboration was particularly exciting because it involved close interaction between experts in computation and virology and medicine. Once we had created the map, we tested its reliability by making hundreds of predictions of how well certain strains might match up and then conducting laboratory tests to check the predictions. It's very gratifying that this basic research also
'"/>

Contact: Todd Hanson
tahanson@lanl.gov
505-665-2085
DOE/Los Alamos National Laboratory
20-Jul-2004


Page: 1 2

Related biology news :

1. Organization for Human Brain Mapping 2004 Annual Meeting
2. Mapping a road to understanding human health
3. Organization for Human Brain Mapping annual meeting abstract highlights
4. Organization for Human Brain Mapping 2003 Annual Meeting
5. Mapping proteins
6. Mapping genes for schizophrenia in the South Pacific
7. Elementary Students Mapping Virginia Wildlife
8. Rare Brain Mapping Procedure Provides Unique Picture Of Two Areas Concerned With Language Processing and Production
9. Subterranean Mapping Method Will Find Homes For Pollution-Eating Bacteria
10. Mapping The Way To A Bigger Prawn
11. Brain Mapping In Real Time

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/22/2019)... (PRWEB) , ... October 21, 2019 , ... Join ... MS, Director of Bioanalytical in a live session on Thursday, October 31, ... CRO partner. , A good CRO partner should have expertise in method development, ...
(Date:10/17/2019)... (PRWEB) , ... October 15, 2019 , ... ... Prepared Media for the Microbiological Community”. , Microbiology International currently manufactures ready-to-use culture ... company also offers pre-poured agar plates & liquid supplements. , This major step ...
(Date:10/15/2019)... ... 2019 , ... Erchonia, the global leader in the manufacturing ... in Orlando & 18th Annual Golf Tournament. The invite-only, four-day event starts ... Melbourne. , The first day will kick off with training and roundtable discussions ...
Breaking Biology News(10 mins):
(Date:10/22/2019)... , ... October 22, 2019 , ... nQ Medical, Inc. ... School’s 2019 Most Fundable Companies List which was announced at a showcase event yesterday ... million in annual revenue, strong business plans, and impressive near-term growth projections to be ...
(Date:10/22/2019)... N.J. (PRWEB) , ... October 22, 2019 , ... Catalent, ... Clinical Supply Services and Drug Product Technologies Integration, will participate in a panel session ... Conference (HPCLC), to be held at the Gwen Hotel, Chicago, on Oct. 28-30, 2019. ...
(Date:10/22/2019)... LOS ANGELES (PRWEB) , ... October 22, 2019 ... ... software provider, today announced integration of the Alertus Mass Notification System into its ... critical infrastructure to the Enplug platform, making it possible for users to leverage ...
(Date:10/22/2019)... ... , ... DermBiont, a clinical stage microbiome biotechnology company developing ... safety endpoints, with no application site reactions and no adverse events, in a ... tinea pedis (athlete’s foot). Additionally, the trial demonstrated a clinical response with improvement ...
Breaking Biology Technology:
Cached News: