HOME >> BIOLOGY >> NEWS
Marijuana use could cause tubal pregnancies

Marijuana use may increase the risk of ectopic (tubal) pregnancies, researchers at Vanderbilt University Medical Center reported this week.

The researchers studied CB1, a "cannabinoid" receptor that binds the main active chemical for marijuana, delta-9-tetrahydrocannabinol (THC).

In pregnant mice that lacked the gene for the receptor, or in which the receptor was blocked, the embryo failed to go through the oviduct the tube leading from the ovaries to the uterus. The same thing happened in normal mice when the receptor was over-stimulated.

The study, published in the current issue of the journal Nature Medicine, describes for the first time how the CB1 receptor in the mouse regulates muscle contraction to move the embryo down the oviduct.

It is not known whether drugs that block or, in the case of marijuana, over-stimulate the CB1 receptor can cause ectopic pregnancy in humans. However, "our results raise caution for women of reproductive ages regarding the chronic use of marijuana for recreation or pain alleviation," the researchers concluded.

The report's senior author, Sudhansu K. Dey, Ph.D., said he also was concerned about the potential impact of an anti-obesity drug, now in clinical trials, that suppresses appetite by blocking the CB1 receptor. Such a drug, if approved, would likely be taken by young women of reproductive age.

"What will happen if they consume anti-CB1 drugs?" asked Dey, Dorothy Overall Wells Professor of Pediatrics and professor of Cell & Developmental Biology and Pharmacology at Vanderbilt University Medical Center.

According to the U.S. Centers for Disease Control and Prevention, about 100,000 ectopic pregnancies occur in the United States each year (out of more than 6 million total pregnancies) and account for about 9 percent of all pregnancy-related deaths in the country. Risk factors include pelvic inflammatory disease, which can scar the fallopian tubes, and smoking.

At the same time, s
'"/>

Contact: Clinton Colmenares
clinton.colmenares@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center
27-Sep-2004


Page: 1 2 3

Related biology news :

1. Marijuana ingredient inhibits VEGF pathway required for brain tumor blood vessels
2. Marijuana receptor gene abnormality in schizophrenia
3. Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
4. Circulation of disaster myths in Haiti could hinder appropriate disposal of bodies
5. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
6. Gene chips research in cotton could lead to superior variety
7. Groundbreaking research could ignite new solutions to heat transfer in nano-devices
8. Bullish chemical could repel yellow fever mosquitoes
9. Termites could hold the key to self-sufficient buildings
10. Wastewater could treat itself, power city
11. Sugar-coated sea urchin eggs could have sweet implications for human fertility

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/18/2019)... ... April 18, 2019 , ... As the industry ... popular trial design that have the potential to increase patient recruitment and retention. ... sponsors due to the complexity of regulations, potential cost implications and a multitude ...
(Date:4/18/2019)... CREEK, Calif. (PRWEB) , ... April 18, 2019 ... ... for the healthcare industry, today announced the launch of mSource® AI Contract Text ... extract deep knowledge of Medpricer customers’ supplier contracts, truly optimizing purchased services spend ...
(Date:4/17/2019)... ... April 17, 2019 , ... Quartesian LLC, a ... clinical trial sponsors, has entered into a multi-year agreement with Medrio, a leading ... member of Medrio’s Certified Partner Program, to leverage the full range of Medrio’s ...
Breaking Biology News(10 mins):
(Date:4/18/2019)... Mass. (PRWEB) , ... April 18, 2019 , ... ... fossil fuels, a research team that includes a chemical engineer at Worcester Polytechnic ... exotic microorganism that may make it possible to manufacture isobutanol and other biofuels ...
(Date:4/16/2019)... , ... April 16, 2019 , ... ... Sources and their project partner, the U.S. Army Center for Environmental Health Research ... Biomonitor Through Combined In-Licensing/Out-Licensing.” , Blue Sources, a veteran-owned company located at the ...
(Date:4/16/2019)... ... April 16, 2019 , ... Fulcrum ... today announced that Bank South Pacific (BSP), the largest regionally owned bank in ... awarded Fulcrum a contract to deliver a fingerprint-based Know Your Customer (KYC) banking ...
(Date:4/15/2019)... ... April 15, 2019 , ... Sirrus, Inc., a developer of ... plant expansion to increase production of methylene malonate monomers and oligomers. , The ... Sirrus’ full-scale production facility, which is scheduled to break ground in 2019. “The ...
Breaking Biology Technology:
Cached News: