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Maxygen subsidiary Verdia announces discovery and improvement of glyphosate tolerance gene

performed traditional means to modify genes and proteins that typically attempt to predict sequence-function relations.

"The increase in activity would never have been possible to achieve using traditional technologies to improve genes such as random mutagenesis and rational design," said Linda Castle, Ph.D. "This demonstration of improved glyphosate tolerance should be applicable to many crops. Further, this study validates our ability to create novel commercial opportunities in crop protection and plant quality traits for ourselves and our partners."

"I am extremely proud of the scientific accomplishments that Maxygen and Verdia have made," said Russell Howard, Ph.D., Chief Executive Officer of Maxygen. "Our MolecularBreedingTM directed evolution platform continues to deliver success in creating valuable commercial properties in genes and proteins for novel business applications."

About Verdia
Verdia is dedicated to becoming a global leader in providing proprietary product solutions to important commercial problems in plant-based businesses through the application of advanced trait optimization methods. Verdia has validated the use of the MolecularBreedingTM directed evolution platform in agriculture through its strategic alliances with industry leaders, including Pioneer Hi-Bred, Syngenta and Delta & Pine Land Company. In addition to the product candidates in development with its partners, Verdia has a pipeline of over 10 potential agriculture products in various stages of development.

About Maxygen
Maxygen, Inc., headquartered in Redwood City, California, is focused on creating novel products using its integrated proprietary technologies for human therapeutics and industrial applications. Maxygen's technologies bring together advances in molecular biology and protein modification to create novel biotechnology products.


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Contact: Jeannine Medeiros
jeannine.medeiros@maxygen.com
650-298-5853
Maxygen, Inc.
21-May-2004


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