HOME >> BIOLOGY >> NEWS
Measuring alcohol levels in breath, blood and now the brain

  • The brain is a critical organ system through which alcohol's effects can lead to intoxication, tolerance and dependence.
  • Scientists have found a new means to measure directly alcohol concentrations throughout the brain.
  • The technology is called proton (1H) magnetic resonance spectroscopy (MRS).
  • 1H MRS can be used to study closely the physical interactions of alcohol and brain membranes. Most people know about the standard methods used to measure alcohol concentrations in breath and blood, even if they haven't personally experienced apprehension for driving while impaired (DWI). A study in the August issue of Alcoholism: Clinical & Experimental Research has refined this ability even further, using proton (1H) magnetic resonance spectroscopy (MRS) to directly measure alcohol concentrations throughout the brain. While this new capability won't be applied any time soon to suspect DWI offenders, it will help researchers who seek to understand the biological basis for alcohol abuse.

    "The scientific community is still uncertain about how exactly alcohol causes intoxication, tolerance, and dependence," said Marc J. Kaufman, assistant professor of psychiatry at Harvard Medical School and associate research pharmacologist at McLean Hospital. He explained that researchers believe that alcohol's effects are produced by its interaction with brain membranes. Membranes contain protein elements called "receptors" that communicate neuronal activity, allowing us to move, feel, think, and remember. In order to function correctly, receptors must be correctly positioned in membranes. Alcohol appears to adhere to or stick to membranes, thereby disrupting receptor positioning, which leads to altered brain function, intoxication, tolerance, and the development of alcohol problems.

    "For the first time," said Kaufman, "this study documents in the living human brain this adherence phenomenon, called the 'magnetization transfer' effect
    '"/>



  • Contact: Dieter J. Meyerhoff, Ph.D.
    djmey@itsa.ucsf.edu
    415-221-4810 x4803
    Alcoholism: Clinical & Experimental Research
    13-Aug-2000


    Page: 1 2 3 4

    Related biology news :

    1. Measuring artificial viruses to improve disease detection
    2. Measuring blood sugar with a wave of the arm
    3. Measuring perchlorate levels in lettuce
    4. Measuring the muscle: new study by Scripps researchers depicts how the tunas body is built for speed
    5. Echocardiography Is Effective In Measuring Microvascular Damage From Heart Attacks
    6. Microsurgery Made More Accurate With Virtual Measuring Tool
    7. A liking for sweets, combined with novelty seeking, may predict alcoholism
    8. Genes can influence both alcohol consumption and dependence
    9. Infant rats eagerly accept high concentrations of alcohol upon first exposure
    10. Acamprosate: potential medication for treating alcoholism
    11. Antioxidants during pregnancy may help prevent birth defects tied to alcohol

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:3/26/2019)... (PRWEB) , ... March 26, 2019 , ... ... proud to introduce the four recipients of the Society's 2019 Outstanding Achievement Award, ... four awards will be presented at the ASGCT 22nd Annual Meeting . ...
    (Date:3/25/2019)... ... March 25, 2019 , ... ... contract research organisation focused on advancing drug discovery, have announced a collaboration to ... Tissue clearing methods, which are essential to get a better view of complex ...
    (Date:3/18/2019)... ... March 18, 2019 , ... Periodontal disease, where bacterial infection of ... 50% of the US population. Making this disease particularly challenging to treat is ... the cells are enmeshed in a sticky extracellular material that makes them more resistant ...
    Breaking Biology News(10 mins):
    (Date:4/8/2019)... ... April 09, 2019 , ... To support the ... Chan Zuckerberg Biohub (CZ Biohub) has chosen Geneious Biologics to help them analyze ... CZ Biohub’s efforts to establish new approaches to inform the discovery of antibody-based ...
    (Date:3/27/2019)... ... , ... In honor of National Nutrition Month, Lajollacooks4u has collaborated with the ... good nutrition. This month, Chef Jodi Abel appeared on two segments on KUSI’s ... first segment addressed the nutritional value of USDA’s MyPlate, a nutrition guide that simplifies ...
    (Date:3/19/2019)... , ... March 19, 2019 , ... ... learning cloud solutions, today announced it has extended its managed services offering to ... colocation data centers that are part of the NVIDIA DGX-Ready Data Center program ...
    (Date:3/19/2019)... SAN JOSE, Calif. (PRWEB) , ... March 19, ... ... provider of multi-GPU deep learning cloud solutions, today announced it has begun offering ... cloud service offerings. Customers can utilize DGX-1, designed to provide the highest performance ...
    Breaking Biology Technology:
    Cached News: