HOME >> BIOLOGY >> NEWS
Mechanism For Fungal Adherence Found, Possible Key To Disease

COLUMBUS, Ohio -- Researchers have discovered that a protein manufactured by the fungus Candida albicans mimics the actions of a specific mammalian protein, perhaps improving the organism's chances to flourish in immune-compromised patients.

In a paper in the latest issue of the journal Science, university researchers reported that the fungi's ability to adhere to cells lining the mucosal surfaces of the mouth depends on the presence of this protein. If the protein is missing, Candida simply cannot hang on.

Candida albicans is one of many microscopic organisms that live inside mammals, including humans. It normally exists at low levels in the gastrointestinal (GI) tract. But in humans, when the immune system is weakened -- as it is in patients with AIDS, people who are HIV-positive, transplant and chemotherapy patients -- the fungus can proliferate.

Some infections, such as thrush in infants and vaginitis in women, can be mild. But among the serious infections patients acquire while in the hospital -- so-called nosocomial infections -- Candida ranks among the top five pathogens and is potentially fatal.

Occasionally, these outbreaks can breach the GI tract and infiltrate the bloodstream and solid organs, causing the latter to shut down because of tissue damage and the sheer quantity of fungus present.

Paula Sundstrom, an associate
'"/>

Contact: Paula Sundstrom
Sundstrom.1@osu.edu
614-292-6252
Ohio State University
5-Mar-1999


Page: 1 2 3 4 5

Related biology news :

1. Mechanism controls movement of cell structures
2. Mechanism to overcome Gleevec resistance demonstrated
3. Mechanism that enables fetus to survive in mother under study
4. Mechanism believed found that regulates movement within cells
5. Mechanism for generating autoimmunity-suppressing cells identified
6. Mechanism found that appears to keep body tissues together
7. Discovery Of Mechanism Causing Colon Cancer
8. Researchers Discover Mechanism Of Cleft Palate Development
9. The Origins Of Hereditary Breast Cancer -- Studies With Knock-Out Mice Reveal Underlying Mechanisms
10. Researchers Identify Mechanism That May Regulate Protein Involved In Sex Differentiation, Stress, Hunger
11. Reversible Process For Forming Supramolecular Polymers Could Be The Basis Of Fibers, Molecular Transport Mechanisms

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... Research and Markets has announced the addition of the ... Industry Forecast to 2025" report to their offering. ... The Global Biometric Vehicle Access ... 15.1% over the next decade to reach approximately $1,580 million by ... and forecasts for all the given segments on global as well ...
(Date:3/22/2017)... Lithuania , March 21, 2017   ... and object recognition technologies, today announced the release ... kit (SDK), which provides improved facial recognition using ... cameras on a single computer. The new version ... to improve accuracy, and it utilizes a Graphing ...
(Date:3/20/2017)... , March 20, 2017 At this year,s CeBIT ... -based biometrics manufacturer DERMALOG. The Chancellor came to the DERMALOG stand together ... is this year,s CeBIT partner country. At the largest German biometrics company ... use: fingerprint, face and iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
Breaking Biology News(10 mins):
(Date:6/19/2017)... ... , ... A colony of healthy honey bees is like a superorganism--individual bees ... nectar containing nutrients necessary for growth and survival. Better nutrition gives the colony a ... to a decline in honey bee health. Sick and weakened bees diminish the colony's ...
(Date:6/16/2017)... ... 16, 2017 , ... Cambridge Semantics , the leading ... Smart Data Lake® (Anzo SDL) solution was named a finalist in the ... Information Industry Association (SIIA) CODiE Awards. , Finalists represent the best products, ...
(Date:6/15/2017)... ... June 15, 2017 , ... New resistant ... new options for managing Palmer amaranth and other broadleaf weeds resistant to glyphosate. ... are necessary. Auxin herbicides are known to drift and to cause harm to ...
(Date:6/15/2017)... ... June 15, 2017 , ... The ... an artist’s journey through creative experimentation and interdisciplinary collaboration. Feature Creep, a solo ... 22nd. An opening reception will be held at EKG, located at 3600 Market ...
Breaking Biology Technology:
Cached News: